LOCUS       AJF01463.1               314 aa    PRT              BCT 20-JUN-2017
DEFINITION  Mycobacterium tuberculosis H37RvSiena Oxidative stress
            response regulatory protein OxyS protein.
ACCESSION   CP007027-119
PROTEIN_ID  AJF01463.1
SOURCE      Mycobacterium tuberculosis H37RvSiena
  ORGANISM  Mycobacterium tuberculosis H37RvSiena
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1  (bases 1 to 4410911)
  AUTHORS   Santoro,F., Guerrini,V., Lazzeri,E., Iannelli,F. and Pozzi,G.
  TITLE     Genomic polymorphisms in a Laboratory Isolate of Mycobacterium
            tuberculosis Reference Strain H37Rv (ATCC27294)
  JOURNAL   New Microbiol. 40 (1), 62-69 (2017)
   PUBMED   27819398
REFERENCE   2  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-DEC-2013) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
REFERENCE   3  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-FEB-2015) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
  REMARK    Protein update by submitter
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            Annotation modified by submitter.
            
            ##Assembly-Data-START##
            Assembly Method       :: Ray v. 2.3.1
            Coverage              :: 300
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 12/30/2013 09:28:23
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS+
            Annotation Software revision :: 2.3 (rev. 422554)
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA;
                                            repeat_region
            Genes                        :: 4,146
            CDS                          :: 4,050
            Pseudo Genes                 :: 42
            CRISPR Arrays                :: 2
            rRNAs                        :: 3 (5S, 16S, 23S)
            tRNAs                        :: 45
            ncRNA                        :: 6
            Frameshifted Genes           :: 34
            ##Genome-Annotation-Data-END##
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37RvSiena"
                     /mol_type="genomic DNA"
                     /strain="H37RvSiena"
                     /db_xref="taxon:1437856"
     protein         /gene="oxyS"
                     /locus_tag="Y980_0117"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00044"
                     /note="Rv0117, (MTV031.11) OxyS, oxidative stress response
                     protein regulatory protein, LysR family (see citation
                     below). Similar to many transcription regulators and OxyR,
                     the oxidative stress response protein of many bacteria.
                     Contains LysR family signature at N-terminus. Also
                     contains helix-turn-helix motif at aa 16-37 (Score 1543,
                     +4.44 SD). Belongs to the LysR family of transcriptional
                     regulators. OXYR is required for the induction of a
                     regulon of hydrogen peroxide inducible genes such as
                     catalase, glutathione-reductase, etc."
                     /transl_table=11
                     /db_xref="GOA:O33175"
                     /db_xref="HSSP:Q9WXC7"
                     /db_xref="InterPro:IPR000847"
                     /db_xref="InterPro:IPR005119"
                     /db_xref="InterPro:IPR011991"
                     /db_xref="UniProtKB/TrEMBL:O33175"
BEGIN
        1 MLFRQLEYFV AVAQERHFAR AAEKCYVSQP ALSSAIAKLE RELNVTLINR GHSFEGLTRE
       61 GERLVVWAKR ILAEHAAFKA EVDAVRSGIT GTLRLGTVPT ASTTASLVLS AFCSAHPLAK
      121 VQVCSRLAAT ELYRRLREFE LDAVIVHPET QDSDDVDLVP LYEEQYVLLS PADMLPPGTS
      181 TLVWRDAAQL PLALLTADMR DRQVIDAAFA DHAVSAIPQV ETDSVASLFA QVATGNWASI
      241 VPHTWLWAMP MSGPTGGEIR AVELVDPVLK AQIALATNAL GPGSPVARAL ITCAQALALN
      301 EFFDTQLRGI TRRR
//