LOCUS       AJF01460.1               190 aa    PRT              BCT 20-JUN-2017
DEFINITION  Mycobacterium tuberculosis H37RvSiena putative D-alpha,
            beta-D-heptose-1,7-biphosphate phosphatase GmhB (D-glycero-
            D-manno-heptose 7-phosphate kinase) protein.
ACCESSION   CP007027-116
PROTEIN_ID  AJF01460.1
SOURCE      Mycobacterium tuberculosis H37RvSiena
  ORGANISM  Mycobacterium tuberculosis H37RvSiena
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1  (bases 1 to 4410911)
  AUTHORS   Santoro,F., Guerrini,V., Lazzeri,E., Iannelli,F. and Pozzi,G.
  TITLE     Genomic polymorphisms in a Laboratory Isolate of Mycobacterium
            tuberculosis Reference Strain H37Rv (ATCC27294)
  JOURNAL   New Microbiol. 40 (1), 62-69 (2017)
   PUBMED   27819398
REFERENCE   2  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-DEC-2013) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
REFERENCE   3  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-FEB-2015) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
  REMARK    Protein update by submitter
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            Annotation modified by submitter.
            
            ##Assembly-Data-START##
            Assembly Method       :: Ray v. 2.3.1
            Coverage              :: 300
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 12/30/2013 09:28:23
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS+
            Annotation Software revision :: 2.3 (rev. 422554)
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA;
                                            repeat_region
            Genes                        :: 4,146
            CDS                          :: 4,050
            Pseudo Genes                 :: 42
            CRISPR Arrays                :: 2
            rRNAs                        :: 3 (5S, 16S, 23S)
            tRNAs                        :: 45
            ncRNA                        :: 6
            Frameshifted Genes           :: 34
            ##Genome-Annotation-Data-END##
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37RvSiena"
                     /mol_type="genomic DNA"
                     /strain="H37RvSiena"
                     /db_xref="taxon:1437856"
     protein         /gene="gmhB"
                     /locus_tag="Y980_0114"
                     /note="Rv0114, (MTV031.08) Possible
                     gmhB,D-alpha,beta-D-heptose-1,7-biphosphate phosphatase
                     (see citation below), similar to several hypothetical
                     proteins and phosphatases e.g. HIS7_ECOLI|P06987
                     imidazoleglycerol-phosphate dehydratase (355 aa). This
                     region is a possible MT-complex-specific genomic island
                     (See Becq et al., 2007)."
                     /transl_table=11
                     /db_xref="GOA:O53636"
                     /db_xref="InterPro:IPR004446"
                     /db_xref="InterPro:IPR006543"
                     /db_xref="InterPro:IPR006549"
                     /db_xref="InterPro:IPR023214"
                     /db_xref="UniProtKB/Swiss-Prot:O53636"
BEGIN
        1 MVAERAGHQW CLFLDRDGVI NRQVVGDYVR NWRQFEWLPG AARALKKLRA WAPYIVVVTN
       61 QQGVGAGLMS AVDVMVIHRH LQMQLASDGV LIDGFQVCPH HRSQRCGCRK PRPGLVLDWL
      121 GRHPDSEPLL SIVVGDSLSD LELAHNVAAA AGACASVQIG GASSGGVADA SFDSLWEFAV
      181 AVGHARGERG
//