LOCUS       AJF01449.1               752 aa    PRT              BCT 20-JUN-2017
DEFINITION  Mycobacterium tuberculosis H37RvSiena putative cation-
            transporter P-type ATPase B CtpB protein.
ACCESSION   CP007027-105
PROTEIN_ID  AJF01449.1
SOURCE      Mycobacterium tuberculosis H37RvSiena
  ORGANISM  Mycobacterium tuberculosis H37RvSiena
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1  (bases 1 to 4410911)
  AUTHORS   Santoro,F., Guerrini,V., Lazzeri,E., Iannelli,F. and Pozzi,G.
  TITLE     Genomic polymorphisms in a Laboratory Isolate of Mycobacterium
            tuberculosis Reference Strain H37Rv (ATCC27294)
  JOURNAL   New Microbiol. 40 (1), 62-69 (2017)
   PUBMED   27819398
REFERENCE   2  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-DEC-2013) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
REFERENCE   3  (bases 1 to 4410911)
  AUTHORS   Guerrini,V., Santoro,F. and Pozzi,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-FEB-2015) Medical Biotechnology, University of Siena,
            viale Bracci, Policlinico Le Scotte, Siena 53100, Italy
  REMARK    Protein update by submitter
COMMENT     Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            
            Annotation modified by submitter.
            
            ##Assembly-Data-START##
            Assembly Method       :: Ray v. 2.3.1
            Coverage              :: 300
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Provider          :: NCBI
            Annotation Date              :: 12/30/2013 09:28:23
            Annotation Pipeline          :: NCBI Prokaryotic Genome Annotation
                                            Pipeline
            Annotation Method            :: Best-placed reference protein set;
                                            GeneMarkS+
            Annotation Software revision :: 2.3 (rev. 422554)
            Features Annotated           :: Gene; CDS; rRNA; tRNA; ncRNA;
                                            repeat_region
            Genes                        :: 4,146
            CDS                          :: 4,050
            Pseudo Genes                 :: 42
            CRISPR Arrays                :: 2
            rRNAs                        :: 3 (5S, 16S, 23S)
            tRNAs                        :: 45
            ncRNA                        :: 6
            Frameshifted Genes           :: 34
            ##Genome-Annotation-Data-END##
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis H37RvSiena"
                     /mol_type="genomic DNA"
                     /strain="H37RvSiena"
                     /db_xref="taxon:1437856"
     protein         /gene="ctpB"
                     /locus_tag="Y980_0103c"
                     /experiment="EXISTENCE: identified in proteomics study"
                     /inference="protein motif:PROSITE:PS00154"
                     /inference="protein motif:PROSITE:PS01047"
                     /note="Rv0103c, (MTCY251.22c) Probable
                     ctpB,cation-transporting P-type ATPase B (transmembrane
                     protein), equivalent to CTPB_MYCLE|P46840
                     cation-transporting P-type ATPase B from Mycobacterium
                     leprae (750 aa). Also highly similar to others e.g.
                     CAB96031.1|AL360055 putative metal transporter ATPase from
                     Streptomyces coelicolor (753 aa); NP_241423.1|NC_002570
                     copper-transporting ATPase from Bacillus halodurans (806
                     aa); etc. Also highly similar to Z46257|MLACEA_7 aceA gene
                     for isocitrate L from Mycobacterium leprae (750 aa). And
                     similar to MTCY251.11 from Mycobacterium tuberculosis.
                     Contains PS01047 Heavy-metal-associated domain, PS00154
                     E1-E2 ATPases phosphorylation site. Belongs to the cation
                     transport ATPases family (E1-E2 ATPases), subfamily IB."
                     /transl_table=11
                     /db_xref="GOA:Q10877"
                     /db_xref="InterPro:IPR000579"
                     /db_xref="InterPro:IPR001757"
                     /db_xref="InterPro:IPR006121"
                     /db_xref="InterPro:IPR008250"
                     /db_xref="InterPro:IPR017969"
                     /db_xref="InterPro:IPR018303"
                     /db_xref="InterPro:IPR023214"
                     /db_xref="InterPro:IPR023299"
                     /db_xref="InterPro:IPR027256"
                     /db_xref="UniProtKB/Swiss-Prot:Q10877"
BEGIN
        1 MAAPVVGDAD LQSVRRIRLD VLGMSCAACA SRVETKLNKI PGVRASVNFA TRVATIDAVG
       61 MAADELCGVV EKAGYHAAPH TETTVLDKRT KDPDGAHARR LLRRLLVAAV LFVPLADLST
      121 LFAIVPSARV PGWGYILTAL AAPVVTWAAW PFHSVALRNA RHRTTSMETL ISVGIVAATA
      181 WSLSSVFGDQ PPREGSGIWR AILNSDSIYL EVAAGVTVFV LAGRYFEARA KSKAGSALRA
      241 LAELGAKNVA VLLPDGAELV IPASELKKRQ RFVTRPGETI AADGVVVDGS AAIDMSAMTG
      301 EAKPVRAYPA ASVVGGTVVM DGRLVIEATA VGADTQFAAM VRLVEQAQTQ KARAQRLADH
      361 IAGVFVPVVF VIAGLAGAAW LVSGAGADRA FSVTLGVLVI ACPCALGLAT PTAMMVASGR
      421 GAQLGIFIKG YRALETIRSI DTVVFDKTGT LTVGQLAVST VTMAGSGTSE RDREEVLGLA
      481 AAVESASEHA MAAAIVAASP DPGPVNGFVA VAGCGVSGEV GGHHVEVGKP SWITRTTPCH
      541 DAALVSARLD GESRGETVVF VSVDGVVRAA LTIADTLKDS AAAAVAALRS RGLRTILLTG
      601 DNRAAADAVA AQVGIDSAVA DMLPEGKVDV IQRLREEGHT VAMVGDGIND GPALVGADLG
      661 LAIGRGTDVA LGAADIILVR DDLNTVPQAL DLARATMRTI RMNMIWAFGY NVAAIPIAAA
      721 GLLNPLIAGA AMAFSSFFVV SNSLRLRNFG AQ
//