LOCUS ADD39171.1 254 aa PRT VRL 12-OCT-2016 DEFINITION Human betaherpesvirus 5 membrane protein US20 protein. ACCESSION GU937742-153 PROTEIN_ID ADD39171.1 SOURCE Human betaherpesvirus 5 (HHV-5) ORGANISM Human betaherpesvirus 5 Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Orthoherpesviridae; Betaherpesvirinae; Cytomegalovirus; Cytomegalovirus humanbeta5. REFERENCE 1 (bases 1 to 235404) AUTHORS Davison,A.J., Akter,P., Cunningham,C., Dolan,A., Addison,C., Dargan,D.J., Hassan-Walker,A.F., Emery,V.C., Griffiths,P.D. and Wilkinson,G.W. TITLE Homology between the human cytomegalovirus RL11 gene family and human adenovirus E3 genes JOURNAL J. Gen. Virol. 84 (PT 3), 657-663 (2003) PUBMED 12604818 REFERENCE 2 (bases 1 to 235404) AUTHORS Akter,P., Cunningham,C., McSharry,B.P., Dolan,A., Addison,C., Dargan,D.J., Hassan-Walker,A.F., Emery,V.C., Griffiths,P.D., Wilkinson,G.W. and Davison,A.J. TITLE Two novel spliced genes in human cytomegalovirus JOURNAL J. Gen. Virol. 84 (PT 5), 1117-1122 (2003) PUBMED 12692276 REFERENCE 3 (bases 1 to 235404) AUTHORS Dolan,A., Cunningham,C., Hector,R.D., Hassan-Walker,A.F., Lee,L., Addison,C., Dargan,D.J., McGeoch,D.J., Gatherer,D., Emery,V.C., Griffiths,P.D., Sinzger,C., McSharry,B.P., Wilkinson,G.W. and Davison,A.J. TITLE Genetic content of wild-type human cytomegalovirus JOURNAL J. Gen. Virol. 85 (PT 5), 1301-1312 (2004) PUBMED 15105547 REFERENCE 4 (bases 1 to 235404) AUTHORS Davison,A.J. TITLE Human cytomegalovirus RL11 gene family: variation, recombination and transcription JOURNAL Unpublished REFERENCE 5 (bases 1 to 235404) AUTHORS Davison,A.J. TITLE Direct Submission JOURNAL Submitted (26-FEB-2010) MRC Virology Unit, Church Street, Glasgow G11 5JR, UK REFERENCE 6 (bases 1 to 235404) AUTHORS Davison,A.J. TITLE Direct Submission JOURNAL Submitted (12-OCT-2016) MRC Virology Unit, Church Street, Glasgow G11 5JR, UK REMARK Sequence update by submitter COMMENT On Oct 12, 2016 this sequence version replaced GU937742.1. The original gene nomenclature has been retained. Genes presumably inherited from the common ancestor of alpha-, beta- and gammaherpesviruses (core genes), from the common ancestor of beta- and gammaherpesviruses (betagamma genes), or from the common ancestor of betaherpesviruses (beta genes) are indicated. A standard protein nomenclature has been applied so that orthologs have the same name in all herpesviruses. FEATURES Qualifiers source /organism="Human betaherpesvirus 5" /mol_type="genomic DNA" /strain="Toledo" /isolation_source="urine from a congenitally infected infant" /host="Homo sapiens" /db_xref="taxon:10359" /country="USA" /collection_date="1984" /note="passaged several times in human fibroblasts; contains inversion of 14336 bp region (genes UL128 to UL133); 3 genes are mutated (RL13, UL9 and UL128); acronym: HCMV; acronym: HHV-5" protein /gene="US20" /note="type 3 membrane protein; 7 transmembrane domains; possibly involved in virion morphogenesis; US12 family" BEGIN 1 MQAQEANALL LSRMEALEWF KKFTVWLRVY AIFIFQLAFS FGLGSVFWLG FPQNRNFCVE 61 NYSFFLTVLV PIVCMFITYT LGNEHPSNAT VLFIYLLANS LTAAIFQMCS ESRVLVGSYV 121 MTLALFISFT GLAFLGGRDR RRWKCISCVY VVMLLSFLTL ALLSDADWLQ KIVVTLCAFS 181 ISFFLGILAY DSLMVIFFCP PNQCIRHAVC LYLDSMAIFL TLLLMLSGPR WISLSDGASL 241 DNGTLTAAST TGTS //