LOCUS ADD39143.2 584 aa PRT VRL 12-OCT-2016 DEFINITION Human betaherpesvirus 5 deoxyribonuclease protein. ACCESSION GU937742-93 PROTEIN_ID ADD39143.2 SOURCE Human betaherpesvirus 5 (HHV-5) ORGANISM Human betaherpesvirus 5 Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Orthoherpesviridae; Betaherpesvirinae; Cytomegalovirus; Cytomegalovirus humanbeta5. REFERENCE 1 (bases 1 to 235404) AUTHORS Davison,A.J., Akter,P., Cunningham,C., Dolan,A., Addison,C., Dargan,D.J., Hassan-Walker,A.F., Emery,V.C., Griffiths,P.D. and Wilkinson,G.W. TITLE Homology between the human cytomegalovirus RL11 gene family and human adenovirus E3 genes JOURNAL J. Gen. Virol. 84 (PT 3), 657-663 (2003) PUBMED 12604818 REFERENCE 2 (bases 1 to 235404) AUTHORS Akter,P., Cunningham,C., McSharry,B.P., Dolan,A., Addison,C., Dargan,D.J., Hassan-Walker,A.F., Emery,V.C., Griffiths,P.D., Wilkinson,G.W. and Davison,A.J. TITLE Two novel spliced genes in human cytomegalovirus JOURNAL J. Gen. Virol. 84 (PT 5), 1117-1122 (2003) PUBMED 12692276 REFERENCE 3 (bases 1 to 235404) AUTHORS Dolan,A., Cunningham,C., Hector,R.D., Hassan-Walker,A.F., Lee,L., Addison,C., Dargan,D.J., McGeoch,D.J., Gatherer,D., Emery,V.C., Griffiths,P.D., Sinzger,C., McSharry,B.P., Wilkinson,G.W. and Davison,A.J. TITLE Genetic content of wild-type human cytomegalovirus JOURNAL J. Gen. Virol. 85 (PT 5), 1301-1312 (2004) PUBMED 15105547 REFERENCE 4 (bases 1 to 235404) AUTHORS Davison,A.J. TITLE Human cytomegalovirus RL11 gene family: variation, recombination and transcription JOURNAL Unpublished REFERENCE 5 (bases 1 to 235404) AUTHORS Davison,A.J. TITLE Direct Submission JOURNAL Submitted (26-FEB-2010) MRC Virology Unit, Church Street, Glasgow G11 5JR, UK REFERENCE 6 (bases 1 to 235404) AUTHORS Davison,A.J. TITLE Direct Submission JOURNAL Submitted (12-OCT-2016) MRC Virology Unit, Church Street, Glasgow G11 5JR, UK REMARK Sequence update by submitter COMMENT On Oct 12, 2016 this sequence version replaced GU937742.1. The original gene nomenclature has been retained. Genes presumably inherited from the common ancestor of alpha-, beta- and gammaherpesviruses (core genes), from the common ancestor of beta- and gammaherpesviruses (betagamma genes), or from the common ancestor of betaherpesviruses (beta genes) are indicated. A standard protein nomenclature has been applied so that orthologs have the same name in all herpesviruses. FEATURES Qualifiers source /organism="Human betaherpesvirus 5" /mol_type="genomic DNA" /strain="Toledo" /isolation_source="urine from a congenitally infected infant" /host="Homo sapiens" /db_xref="taxon:10359" /country="USA" /collection_date="1984" /note="passaged several times in human fibroblasts; contains inversion of 14336 bp region (genes UL128 to UL133); 3 genes are mutated (RL13, UL9 and UL128); acronym: HCMV; acronym: HHV-5" protein /gene="UL98" /note="involved in DNA processing" BEGIN 1 MWGVSSLDYD DDEELTRLLA VWDDEPLSLF LMNTFLLHQE GFRNLPFTVL RLSYAYRIFA 61 KMLRAHGTPV AEDFMTRVAA LARDEGLRDI LGQRHAAEAS RAEIAEALER VAERCDDRHG 121 GSDDYVWLSR LLDLAPNYRQ VELFQLLEKE SRGQSRNSVW HLLRMDTVSA TKFYEAFVSG 181 CLPGAAAADG SGGGGSHYTG SRAGVSPGIQ FGIKHEGLVK TLVECYVMHG REPVRDGLGL 241 LIDPTSGLLG ASMDLCFGVL KQGSGRTLLV EPCARVYEIK CRYKYLRKKE DPFVQNVLRR 301 HDAAAVASLL QSHPVPGVEF RGERETPSAR EFLLSHDAAL FRATLKRARP LKPPEPLREY 361 LADLLYLNKA ECSEVIVFDA KHLNDDNSDG DATTTINASL GLAAGDAAGG GADHHLRGSP 421 GDSPPPIPFE DENTPELLGR LNVYEVARFS LPAFVNPRHQ YYFQMLIQQY VLSQYYIKKH 481 PDPERIDFRD LPTVYLVSAI FREREESELG CELLAGGRVF HCDHIPLLLI VTPVVFDPQF 541 TRHAVSTVLD RWSRDLSRKT NLPIWVPNSA NEYVVSSVPR PVSP //