LOCUS ADD39128.1 560 aa PRT VRL 12-OCT-2016 DEFINITION Human betaherpesvirus 5 tegument protein pp71 protein. ACCESSION GU937742-78 PROTEIN_ID ADD39128.1 SOURCE Human betaherpesvirus 5 (HHV-5) ORGANISM Human betaherpesvirus 5 Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Orthoherpesviridae; Betaherpesvirinae; Cytomegalovirus; Cytomegalovirus humanbeta5. REFERENCE 1 (bases 1 to 235404) AUTHORS Davison,A.J., Akter,P., Cunningham,C., Dolan,A., Addison,C., Dargan,D.J., Hassan-Walker,A.F., Emery,V.C., Griffiths,P.D. and Wilkinson,G.W. TITLE Homology between the human cytomegalovirus RL11 gene family and human adenovirus E3 genes JOURNAL J. Gen. Virol. 84 (PT 3), 657-663 (2003) PUBMED 12604818 REFERENCE 2 (bases 1 to 235404) AUTHORS Akter,P., Cunningham,C., McSharry,B.P., Dolan,A., Addison,C., Dargan,D.J., Hassan-Walker,A.F., Emery,V.C., Griffiths,P.D., Wilkinson,G.W. and Davison,A.J. TITLE Two novel spliced genes in human cytomegalovirus JOURNAL J. Gen. Virol. 84 (PT 5), 1117-1122 (2003) PUBMED 12692276 REFERENCE 3 (bases 1 to 235404) AUTHORS Dolan,A., Cunningham,C., Hector,R.D., Hassan-Walker,A.F., Lee,L., Addison,C., Dargan,D.J., McGeoch,D.J., Gatherer,D., Emery,V.C., Griffiths,P.D., Sinzger,C., McSharry,B.P., Wilkinson,G.W. and Davison,A.J. TITLE Genetic content of wild-type human cytomegalovirus JOURNAL J. Gen. Virol. 85 (PT 5), 1301-1312 (2004) PUBMED 15105547 REFERENCE 4 (bases 1 to 235404) AUTHORS Davison,A.J. TITLE Human cytomegalovirus RL11 gene family: variation, recombination and transcription JOURNAL Unpublished REFERENCE 5 (bases 1 to 235404) AUTHORS Davison,A.J. TITLE Direct Submission JOURNAL Submitted (26-FEB-2010) MRC Virology Unit, Church Street, Glasgow G11 5JR, UK REFERENCE 6 (bases 1 to 235404) AUTHORS Davison,A.J. TITLE Direct Submission JOURNAL Submitted (12-OCT-2016) MRC Virology Unit, Church Street, Glasgow G11 5JR, UK REMARK Sequence update by submitter COMMENT On Oct 12, 2016 this sequence version replaced GU937742.1. The original gene nomenclature has been retained. Genes presumably inherited from the common ancestor of alpha-, beta- and gammaherpesviruses (core genes), from the common ancestor of beta- and gammaherpesviruses (betagamma genes), or from the common ancestor of betaherpesviruses (beta genes) are indicated. A standard protein nomenclature has been applied so that orthologs have the same name in all herpesviruses. FEATURES Qualifiers source /organism="Human betaherpesvirus 5" /mol_type="genomic DNA" /strain="Toledo" /isolation_source="urine from a congenitally infected infant" /host="Homo sapiens" /db_xref="taxon:10359" /country="USA" /collection_date="1984" /note="passaged several times in human fibroblasts; contains inversion of 14336 bp region (genes UL128 to UL133); 3 genes are mutated (RL13, UL9 and UL128); acronym: HCMV; acronym: HHV-5" protein /gene="UL82" /note="upper matrix protein; involved in gene regulation; transcriptional activator; targeted to ND10; targets Rb proteins for ubiquitin-independent proteosomal degradation; DURP family" BEGIN 1 MSQASSSPGE GPSSEAAAIS EAEAASGSFG RLHCQVLRLI TNVEGGSLEA GRLRLLDLRT 61 NIEVSRPSVL CCFQENKSPH DTVDLTDLNI KGRCVVGEQD RLLVDLNNFG PRRLTPGSEN 121 NTVSVLAFAL PLDRVPVSGL HLFQSQRRGG EENRPRVEAR AIIRRTAHYW AVRLTVTPNW 181 RRRTDSSLEA GQIFVSQFAF RAGAIPLTLV DALEQLACSD PNTYIHKTET DERGQWIMLF 241 LHHDSPHPPT SVFLHFSVYT HRAEVVARHN PYPHLRRLPD NGFQLLIPKS FTLTRIHPEY 301 IVQIQNAFET NQTHDTIFFP ENIPGVSIEA GPLPDRVRIT LRVTLTGDQA VHLEHRQPLG 361 RIHFFRRGFW TLTPGKPDKI KRPQVQLRAG LFPRSNVMRG AVSEFLPQSP GLPPTEEEEE 421 EEEEEDDDDD LSSTPTPTPL SEAMFAGFEE ASGDEDSDTQ AGLSRALILT GQRRRSGNNG 481 ALTLVIPSWH VFASLDDLVP LTVSVQHGAL RPTSYLRSDM DGDVRTAADI SSTLRSVPAP 541 RPSPISTAST SSTPRSRPRI //