LOCUS ADD39126.1 709 aa PRT VRL 12-OCT-2016
DEFINITION Human betaherpesvirus 5 capsid maturation protease protein.
ACCESSION GU937742-76
PROTEIN_ID ADD39126.1
SOURCE Human betaherpesvirus 5 (HHV-5)
ORGANISM Human betaherpesvirus 5
Viruses; Duplodnaviria; Heunggongvirae; Peploviricota;
Herviviricetes; Herpesvirales; Orthoherpesviridae;
Betaherpesvirinae; Cytomegalovirus; Cytomegalovirus humanbeta5.
REFERENCE 1 (bases 1 to 235404)
AUTHORS Davison,A.J., Akter,P., Cunningham,C., Dolan,A., Addison,C.,
Dargan,D.J., Hassan-Walker,A.F., Emery,V.C., Griffiths,P.D. and
Wilkinson,G.W.
TITLE Homology between the human cytomegalovirus RL11 gene family and
human adenovirus E3 genes
JOURNAL J. Gen. Virol. 84 (PT 3), 657-663 (2003)
PUBMED 12604818
REFERENCE 2 (bases 1 to 235404)
AUTHORS Akter,P., Cunningham,C., McSharry,B.P., Dolan,A., Addison,C.,
Dargan,D.J., Hassan-Walker,A.F., Emery,V.C., Griffiths,P.D.,
Wilkinson,G.W. and Davison,A.J.
TITLE Two novel spliced genes in human cytomegalovirus
JOURNAL J. Gen. Virol. 84 (PT 5), 1117-1122 (2003)
PUBMED 12692276
REFERENCE 3 (bases 1 to 235404)
AUTHORS Dolan,A., Cunningham,C., Hector,R.D., Hassan-Walker,A.F., Lee,L.,
Addison,C., Dargan,D.J., McGeoch,D.J., Gatherer,D., Emery,V.C.,
Griffiths,P.D., Sinzger,C., McSharry,B.P., Wilkinson,G.W. and
Davison,A.J.
TITLE Genetic content of wild-type human cytomegalovirus
JOURNAL J. Gen. Virol. 85 (PT 5), 1301-1312 (2004)
PUBMED 15105547
REFERENCE 4 (bases 1 to 235404)
AUTHORS Davison,A.J.
TITLE Human cytomegalovirus RL11 gene family: variation, recombination
and transcription
JOURNAL Unpublished
REFERENCE 5 (bases 1 to 235404)
AUTHORS Davison,A.J.
TITLE Direct Submission
JOURNAL Submitted (26-FEB-2010) MRC Virology Unit, Church Street, Glasgow
G11 5JR, UK
REFERENCE 6 (bases 1 to 235404)
AUTHORS Davison,A.J.
TITLE Direct Submission
JOURNAL Submitted (12-OCT-2016) MRC Virology Unit, Church Street, Glasgow
G11 5JR, UK
REMARK Sequence update by submitter
COMMENT On Oct 12, 2016 this sequence version replaced GU937742.1.
The original gene nomenclature has been retained. Genes presumably
inherited from the common ancestor of alpha-, beta- and
gammaherpesviruses (core genes), from the common ancestor of beta-
and gammaherpesviruses (betagamma genes), or from the common
ancestor of betaherpesviruses (beta genes) are indicated. A
standard protein nomenclature has been applied so that orthologs
have the same name in all herpesviruses.
FEATURES Qualifiers
source /organism="Human betaherpesvirus 5"
/mol_type="genomic DNA"
/strain="Toledo"
/isolation_source="urine from a congenitally infected
infant"
/host="Homo sapiens"
/db_xref="taxon:10359"
/country="USA"
/collection_date="1984"
/note="passaged several times in human fibroblasts;
contains inversion of 14336 bp region (genes UL128 to
UL133); 3 genes are mutated (RL13, UL9 and UL128);
acronym: HCMV; acronym: HHV-5"
protein /gene="UL80"
/EC_number="3.4.21.97"
/note="serine protease (N-terminal region); minor scaffold
protein (remainder of protein, clipped near C terminus);
involved in capsid morphogenesis"
BEGIN
1 MTMDEQQPQA VAPVYVGGFL ARYDQSPDEA ELLLPRDVVE HWLYAQSQGQ PSLSVALPLN
61 INHDDTAVVG HVAAMQSVRD GLFCLGCVTS PRFLEIVRRA SEKSELVSRG PVSPLQPDKV
121 VEFLSGSYAG LSLSSRRCDD VEAATSLSGS ETTPFKHVAL CSVGRRRGTL AVYGRDPEWV
181 TQRFPDLTAA DRDGLRAQWQ RCGSTAVDAS GDPFRSDSYG LLGNSVDALY IRERLPKLRY
241 DKQLVGVTER ESYVKASVSP EAACDIKAAS AERSGDSRSQ AATPATGARV PSSSPSPPVE
301 PPSPVQPPAL PASPSVLPAE SPPSLSPSEP AEAASMSHPL SAAVTAATAP PGATVAGASP
361 AVPSLAWPHD GVYLPKDAFF SLLGASRSAA PVMYPGAVAA PPSASPAPLP LPSYPASYGA
421 PVVGYDQLAV RHFADYVDPH YPGWGRRYEP APSLHPSYPV PPPPSPAYYR RRDSPGGMDE
481 PPSGWERYDG GHRGQSQKQH RHGGSGGHNK RRKEAAAASS SSSSDEDLSF PGEAEHGRAR
541 KRLKSHVNSD GGSGGHAGSN QQQQQRYDEL RDAIHELKRD LFAARQSSTL LSAALPAAAS
601 SSPTTTTVCT PTGELTSGGG ETPTALLSGG AKVAERAQAG VVNASCRLAT ASGSEAATAG
661 PSTAGSSSCP ASVVLAAAAA QAAAASQSPP KDMVDLNRRI FVAALNKLE
//