LOCUS ADD39123.1 648 aa PRT VRL 12-OCT-2016 DEFINITION Human betaherpesvirus 5 DNA packaging tegument protein UL25 protein. ACCESSION GU937742-73 PROTEIN_ID ADD39123.1 SOURCE Human betaherpesvirus 5 (HHV-5) ORGANISM Human betaherpesvirus 5 Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Orthoherpesviridae; Betaherpesvirinae; Cytomegalovirus; Cytomegalovirus humanbeta5. REFERENCE 1 (bases 1 to 235404) AUTHORS Davison,A.J., Akter,P., Cunningham,C., Dolan,A., Addison,C., Dargan,D.J., Hassan-Walker,A.F., Emery,V.C., Griffiths,P.D. and Wilkinson,G.W. TITLE Homology between the human cytomegalovirus RL11 gene family and human adenovirus E3 genes JOURNAL J. Gen. Virol. 84 (PT 3), 657-663 (2003) PUBMED 12604818 REFERENCE 2 (bases 1 to 235404) AUTHORS Akter,P., Cunningham,C., McSharry,B.P., Dolan,A., Addison,C., Dargan,D.J., Hassan-Walker,A.F., Emery,V.C., Griffiths,P.D., Wilkinson,G.W. and Davison,A.J. TITLE Two novel spliced genes in human cytomegalovirus JOURNAL J. Gen. Virol. 84 (PT 5), 1117-1122 (2003) PUBMED 12692276 REFERENCE 3 (bases 1 to 235404) AUTHORS Dolan,A., Cunningham,C., Hector,R.D., Hassan-Walker,A.F., Lee,L., Addison,C., Dargan,D.J., McGeoch,D.J., Gatherer,D., Emery,V.C., Griffiths,P.D., Sinzger,C., McSharry,B.P., Wilkinson,G.W. and Davison,A.J. TITLE Genetic content of wild-type human cytomegalovirus JOURNAL J. Gen. Virol. 85 (PT 5), 1301-1312 (2004) PUBMED 15105547 REFERENCE 4 (bases 1 to 235404) AUTHORS Davison,A.J. TITLE Human cytomegalovirus RL11 gene family: variation, recombination and transcription JOURNAL Unpublished REFERENCE 5 (bases 1 to 235404) AUTHORS Davison,A.J. TITLE Direct Submission JOURNAL Submitted (26-FEB-2010) MRC Virology Unit, Church Street, Glasgow G11 5JR, UK REFERENCE 6 (bases 1 to 235404) AUTHORS Davison,A.J. TITLE Direct Submission JOURNAL Submitted (12-OCT-2016) MRC Virology Unit, Church Street, Glasgow G11 5JR, UK REMARK Sequence update by submitter COMMENT On Oct 12, 2016 this sequence version replaced GU937742.1. The original gene nomenclature has been retained. Genes presumably inherited from the common ancestor of alpha-, beta- and gammaherpesviruses (core genes), from the common ancestor of beta- and gammaherpesviruses (betagamma genes), or from the common ancestor of betaherpesviruses (beta genes) are indicated. A standard protein nomenclature has been applied so that orthologs have the same name in all herpesviruses. FEATURES Qualifiers source /organism="Human betaherpesvirus 5" /mol_type="genomic DNA" /strain="Toledo" /isolation_source="urine from a congenitally infected infant" /host="Homo sapiens" /db_xref="taxon:10359" /country="USA" /collection_date="1984" /note="passaged several times in human fibroblasts; contains inversion of 14336 bp region (genes UL128 to UL133); 3 genes are mutated (RL13, UL9 and UL128); acronym: HCMV; acronym: HHV-5" protein /gene="UL77" /note="located on capsid near vertices; possibly stabilizes the capsid and retains the genome; involved in DNA encapsidation" BEGIN 1 MSLLHTFWRL PVAVFFEPHE ENVLRCPERV LRRLLEDAAV ATRGGGWRED VLMDRVRKRY 61 LRQELRDLGH RVQTYCEDLE GRVSEAEALL NQQCELDEGP SPRTLLQPPC RPRSSSPGTG 121 VAGASAVPHG LYSRHDAITG PAAAPSDAVA PSDAVAPSDA VAASAAAGAS STWLAQCAER 181 PLPGNVPSYF GITQNDPFIR FHTDFRGEVV NTMFENASTW TFSFGIWYYR LKRGLYTQPR 241 WKRVYHLAQM DNFSISQELL LGVVNALENV TVYPTYDCVL SDLEAAACLL AAYGHALWEG 301 RDPPDSVATV LGELPQLLPR LADDVSREIA AWEGPVAAGN NYYAYRDSPD LRYYMPLSGG 361 RHYHPGTFDR HVLVRLFHKR GVLQHLPGYG TITEELVQER LSGQVRDDVL SLWSRRLLVG 421 KLGRDVPVFV HEQQYLRSGL TCLASLLLLW KVTNADSVFA PRTGKFTLAD LLGSDAVAGG 481 GLPGGRAGGE EEGYGGRHGR VRNFEFLVQY YIGPWYARDP AVTLSQLFPG LALLAVTESV 541 RSGWDPSRRE DSAGGGDGGG AVLMQLSKSN PVADYMFAQS SKQYGDLRRL EVHDALLFHY 601 EHGLGRLLSV TLPRHRVSTL GSSLFNVNDI YELLYFLVLG FLPSVAVL //