LOCUS ADD39120.1 946 aa PRT VRL 12-OCT-2016
DEFINITION Human betaherpesvirus 5 helicase-primase primase subunit protein.
ACCESSION GU937742-65
PROTEIN_ID ADD39120.1
SOURCE Human betaherpesvirus 5 (HHV-5)
ORGANISM Human betaherpesvirus 5
Viruses; Duplodnaviria; Heunggongvirae; Peploviricota;
Herviviricetes; Herpesvirales; Orthoherpesviridae;
Betaherpesvirinae; Cytomegalovirus; Cytomegalovirus humanbeta5.
REFERENCE 1 (bases 1 to 235404)
AUTHORS Davison,A.J., Akter,P., Cunningham,C., Dolan,A., Addison,C.,
Dargan,D.J., Hassan-Walker,A.F., Emery,V.C., Griffiths,P.D. and
Wilkinson,G.W.
TITLE Homology between the human cytomegalovirus RL11 gene family and
human adenovirus E3 genes
JOURNAL J. Gen. Virol. 84 (PT 3), 657-663 (2003)
PUBMED 12604818
REFERENCE 2 (bases 1 to 235404)
AUTHORS Akter,P., Cunningham,C., McSharry,B.P., Dolan,A., Addison,C.,
Dargan,D.J., Hassan-Walker,A.F., Emery,V.C., Griffiths,P.D.,
Wilkinson,G.W. and Davison,A.J.
TITLE Two novel spliced genes in human cytomegalovirus
JOURNAL J. Gen. Virol. 84 (PT 5), 1117-1122 (2003)
PUBMED 12692276
REFERENCE 3 (bases 1 to 235404)
AUTHORS Dolan,A., Cunningham,C., Hector,R.D., Hassan-Walker,A.F., Lee,L.,
Addison,C., Dargan,D.J., McGeoch,D.J., Gatherer,D., Emery,V.C.,
Griffiths,P.D., Sinzger,C., McSharry,B.P., Wilkinson,G.W. and
Davison,A.J.
TITLE Genetic content of wild-type human cytomegalovirus
JOURNAL J. Gen. Virol. 85 (PT 5), 1301-1312 (2004)
PUBMED 15105547
REFERENCE 4 (bases 1 to 235404)
AUTHORS Davison,A.J.
TITLE Human cytomegalovirus RL11 gene family: variation, recombination
and transcription
JOURNAL Unpublished
REFERENCE 5 (bases 1 to 235404)
AUTHORS Davison,A.J.
TITLE Direct Submission
JOURNAL Submitted (26-FEB-2010) MRC Virology Unit, Church Street, Glasgow
G11 5JR, UK
REFERENCE 6 (bases 1 to 235404)
AUTHORS Davison,A.J.
TITLE Direct Submission
JOURNAL Submitted (12-OCT-2016) MRC Virology Unit, Church Street, Glasgow
G11 5JR, UK
REMARK Sequence update by submitter
COMMENT On Oct 12, 2016 this sequence version replaced GU937742.1.
The original gene nomenclature has been retained. Genes presumably
inherited from the common ancestor of alpha-, beta- and
gammaherpesviruses (core genes), from the common ancestor of beta-
and gammaherpesviruses (betagamma genes), or from the common
ancestor of betaherpesviruses (beta genes) are indicated. A
standard protein nomenclature has been applied so that orthologs
have the same name in all herpesviruses.
FEATURES Qualifiers
source /organism="Human betaherpesvirus 5"
/mol_type="genomic DNA"
/strain="Toledo"
/isolation_source="urine from a congenitally infected
infant"
/host="Homo sapiens"
/db_xref="taxon:10359"
/country="USA"
/collection_date="1984"
/note="passaged several times in human fibroblasts;
contains inversion of 14336 bp region (genes UL128 to
UL133); 3 genes are mutated (RL13, UL9 and UL128);
acronym: HCMV; acronym: HHV-5"
protein /gene="UL70"
/note="involved in DNA replication"
BEGIN
1 MTLVLFATEY DSAHIVANVL SQTPTDHCVF PLLVKHQVSR RVYFCLQTQK CSDSRRVAPV
61 FAVNNETLQL SRYLAARQPI PLSALIASLD EAETQPLYRH LFRTPVLSPE HGGEVREFKH
121 LVYFHHAAVL RHLNQVFLCP TSPSWFISVF GHTEGQVLLT MAYYLFEGQY STISTVEEYV
181 RSFCTRDLGT IIPTHASMGE FARLLLGSPF RQRVSAFVAY AVARNRRDYT ELEQVDTQIN
241 AFRERARLPD TVCVHYVYLA YRTALARARL LEYRRVVAYD ADAAPEAQCT REPGFLGRRL
301 STELLDVMQK YFSLDNFLHD YVETHLLRLD ESPHSATSPH GLGLAGYGGR IDGTHLAGFF
361 GTSTQLARQL ERINTLSESV FSPLERSLSG LLRLCASLRT AQTYTTGTLT RYSQRRYLLP
421 EPALAPLLER PLPVYRVHLP NDQHVFCAVA SETWHRSLFP RDLLRHVPDS RFSDEALTET
481 VWLHDDDVAS TSPETQFYYT RHEVFNERLP VFNFVADFDL RLRDGVSGLA RHTVFELCRG
541 LRRVWMTVWA SLFGYTHPDR HPVYFFKSAC PPNSVPVDAA GAPFDDDDYL DYRDERDTEE
601 DEDGKENKNN VPDNGVFQKT TSSVDTSPPY CRCKGKLGLR IITPFPACTV AVHPSVLRAV
661 AQVLNHAVCL DAELHTLLDP ISHPESSLDT GIYHHGRSVR LPYMYKMDQD DGYFMHRRLL
721 PLFIVPDAYR EHPLGFVRAQ LDLRNLLHHH PPHDLPALPL SPPPRVILSV RDKICPSTEA
781 NFIETRSLNV TRYRRRGLTE VLAYHLYGGD GATAAAISDT DLQRLVVTRV WPPLLEHLTQ
841 HYEPHVSEQF TAPHVLLFQP HGACCVAVKR RDGARTRDFR CLNYTHRNPQ ETVQVFIDLR
901 TEHSYALWAS LWSRCFTKKC HSNAKNVHIS IKIRPPDAPM PPATAV
//