LOCUS ADD39105.1 906 aa PRT VRL 12-OCT-2016
DEFINITION Human betaherpesvirus 5 ribonucleotide reductase subunit 1 protein.
ACCESSION GU937742-50
PROTEIN_ID ADD39105.1
SOURCE Human betaherpesvirus 5 (HHV-5)
ORGANISM Human betaherpesvirus 5
Viruses; Duplodnaviria; Heunggongvirae; Peploviricota;
Herviviricetes; Herpesvirales; Orthoherpesviridae;
Betaherpesvirinae; Cytomegalovirus; Cytomegalovirus humanbeta5.
REFERENCE 1 (bases 1 to 235404)
AUTHORS Davison,A.J., Akter,P., Cunningham,C., Dolan,A., Addison,C.,
Dargan,D.J., Hassan-Walker,A.F., Emery,V.C., Griffiths,P.D. and
Wilkinson,G.W.
TITLE Homology between the human cytomegalovirus RL11 gene family and
human adenovirus E3 genes
JOURNAL J. Gen. Virol. 84 (PT 3), 657-663 (2003)
PUBMED 12604818
REFERENCE 2 (bases 1 to 235404)
AUTHORS Akter,P., Cunningham,C., McSharry,B.P., Dolan,A., Addison,C.,
Dargan,D.J., Hassan-Walker,A.F., Emery,V.C., Griffiths,P.D.,
Wilkinson,G.W. and Davison,A.J.
TITLE Two novel spliced genes in human cytomegalovirus
JOURNAL J. Gen. Virol. 84 (PT 5), 1117-1122 (2003)
PUBMED 12692276
REFERENCE 3 (bases 1 to 235404)
AUTHORS Dolan,A., Cunningham,C., Hector,R.D., Hassan-Walker,A.F., Lee,L.,
Addison,C., Dargan,D.J., McGeoch,D.J., Gatherer,D., Emery,V.C.,
Griffiths,P.D., Sinzger,C., McSharry,B.P., Wilkinson,G.W. and
Davison,A.J.
TITLE Genetic content of wild-type human cytomegalovirus
JOURNAL J. Gen. Virol. 85 (PT 5), 1301-1312 (2004)
PUBMED 15105547
REFERENCE 4 (bases 1 to 235404)
AUTHORS Davison,A.J.
TITLE Human cytomegalovirus RL11 gene family: variation, recombination
and transcription
JOURNAL Unpublished
REFERENCE 5 (bases 1 to 235404)
AUTHORS Davison,A.J.
TITLE Direct Submission
JOURNAL Submitted (26-FEB-2010) MRC Virology Unit, Church Street, Glasgow
G11 5JR, UK
REFERENCE 6 (bases 1 to 235404)
AUTHORS Davison,A.J.
TITLE Direct Submission
JOURNAL Submitted (12-OCT-2016) MRC Virology Unit, Church Street, Glasgow
G11 5JR, UK
REMARK Sequence update by submitter
COMMENT On Oct 12, 2016 this sequence version replaced GU937742.1.
The original gene nomenclature has been retained. Genes presumably
inherited from the common ancestor of alpha-, beta- and
gammaherpesviruses (core genes), from the common ancestor of beta-
and gammaherpesviruses (betagamma genes), or from the common
ancestor of betaherpesviruses (beta genes) are indicated. A
standard protein nomenclature has been applied so that orthologs
have the same name in all herpesviruses.
FEATURES Qualifiers
source /organism="Human betaherpesvirus 5"
/mol_type="genomic DNA"
/strain="Toledo"
/isolation_source="urine from a congenitally infected
infant"
/host="Homo sapiens"
/db_xref="taxon:10359"
/country="USA"
/collection_date="1984"
/note="passaged several times in human fibroblasts;
contains inversion of 14336 bp region (genes UL128 to
UL133); 3 genes are mutated (RL13, UL9 and UL128);
acronym: HCMV; acronym: HHV-5"
protein /gene="UL45"
/note="enzymatically inactive; tegument protein"
BEGIN
1 MNPADADEEQ RVSSVPAHRC RPGRIPSRGS ETETEESSAE AAADTTGGDD SELEEGPLPG
61 GDKEASAGNT NVSSGVACVA GFTSGGGVVS WRPESPSPDG TPSVLSLTRD SGPAVPSRGG
121 RVSSGLSTFN PAGATRMELD SVEEEDDFGA SLCKVSPPIQ ATRMLMGKKC HCHGYWGKFR
181 FCGVQEPARE LPSDRNALWR EMDTVSRHSA GLGSFRLFQL IMRHGPCLIR HSPRCDLLLG
241 RFYFKANLAR ESRTPLCYAS ELCDESVRRF VLRHMEDLPK LAEETARFVE LAGCWGLYAA
301 ILCLDKVCRQ LHGQDESPGG VFLRIAVALT AAIENSRHSR IYRFHLDARF EGEVLESVLK
361 RCRDGQLSLS TFTMSTVGFD RVPQYDFLIS ADPFSRDASW AAMCKWMSTL SCGVSVSVNV
421 TRLNADVNSV IRCLGGYCDL IREKEVHRPV VRVFVDMWDV AAIRVINFIL KESTSELTGV
481 CYAFNVPSVL MKRYRAREQR YSLFGRPVSR RLSDLGQESA FEKEYSRCEQ SCPKVVVNTD
541 DFLKKMLLCA LKGRASVVFV HHVVKYSIMA DSVCLPPCLS PDMASCHFGE CDMPVQRLTV
601 NVARCVFARS DEQKLHLPDV VLGNTRRYFD LSVLRELVTE AVVWGNARLD ALMSASEWWV
661 ESALEKLRPL HIGVAGLHTA LMRLGFTYFA SWDLIERIFE HMYFAAVRAS VDLCKSGLPR
721 CEWFERTIYQ EGKFIFELYR LPRLSIASAR WEALRADMLE FGLRNCQFLA VGPDDEVAHL
781 WGVTPSVWAS RGTVFEEETV WSLCPPNREC YFPTVVRRPL RVPVVNYAWL EQHQEEGKAT
841 QCLFQAAPAI QNDVEMAAVN LSVFVDQCVA LVFYYDSGMT PDVLLARMLK WYHWRFKVGV
901 YKYCAS
//