LOCUS       ACS93412.1               708 aa    PRT              VRL 09-MAY-2013
DEFINITION  Human betaherpesvirus 5 capsid maturation protease protein.
ACCESSION   GQ221974-76
PROTEIN_ID  ACS93412.1
SOURCE      Human betaherpesvirus 5 (HHV-5)
  ORGANISM  Human betaherpesvirus 5
            Viruses; dsDNA viruses, no RNA stage; Herpesvirales; Herpesviridae;
            Betaherpesvirinae; Cytomegalovirus.
REFERENCE   1  (bases 1 to 235154)
  AUTHORS   Davison,A.J., Akter,P., Cunningham,C., Dolan,A., Addison,C.,
            Dargan,D.J., Hassan-Walker,A.F., Emery,V.C., Griffiths,P.D. and
            Wilkinson,G.W.
  TITLE     Homology between the human cytomegalovirus RL11 gene family and
            human adenovirus E3 genes
  JOURNAL   J. Gen. Virol. 84 (PT 3), 657-663 (2003)
   PUBMED   12604818
REFERENCE   2  (bases 1 to 235154)
  AUTHORS   Akter,P., Cunningham,C., McSharry,B.P., Dolan,A., Addison,C.,
            Dargan,D.J., Hassan-Walker,A.F., Emery,V.C., Griffiths,P.D.,
            Wilkinson,G.W. and Davison,A.J.
  TITLE     Two novel spliced genes in human cytomegalovirus
  JOURNAL   J. Gen. Virol. 84 (PT 5), 1117-1122 (2003)
   PUBMED   12692276
REFERENCE   3  (bases 1 to 235154)
  AUTHORS   Dolan,A., Cunningham,C., Hector,R.D., Hassan-Walker,A.F., Lee,L.,
            Addison,C., Dargan,D.J., McGeoch,D.J., Gatherer,D., Emery,V.C.,
            Griffiths,P.D., Sinzger,C., McSharry,B.P., Wilkinson,G.W. and
            Davison,A.J.
  TITLE     Genetic content of wild-type human cytomegalovirus
  JOURNAL   J. Gen. Virol. 85 (PT 5), 1301-1312 (2004)
   PUBMED   15105547
REFERENCE   4  (bases 1 to 235154)
  AUTHORS   Griffin,C., Wang,E.C., McSharry,B.P., Rickards,C., Browne,H.,
            Wilkinson,G.W. and Tomasec,P.
  TITLE     Characterization of a highly glycosylated form of the human
            cytomegalovirus HLA class I homologue gpUL18
  JOURNAL   J. Gen. Virol. 86 (PT 11), 2999-3008 (2005)
   PUBMED   16227221
REFERENCE   5  (bases 1 to 235154)
  AUTHORS   Cunningham,C., Gatherer,D., Hilfrich,B., Baluchova,K., Dargan,D.J.,
            Thomson,M., Griffiths,P.D., Wilkinson,G.W., Schulz,T.F. and
            Davison,A.J.
  TITLE     Sequences of complete human cytomegalovirus genomes from infected
            cell cultures and clinical specimens
  JOURNAL   J. Gen. Virol. 91 (PT 3), 605-615 (2010)
   PUBMED   19906940
REFERENCE   6  (bases 1 to 235154)
  AUTHORS   Davison,A.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-MAY-2009) MRC Virology Unit, Church Street, Glasgow
            G11 5JR, UK
COMMENT     On or before Aug 17, 2009 this sequence version replaced
            AY446863.1, AY446867.1, AY446875.1, AY169795.2, AY156040.1,
            AY325311.1, DQ195526.1.
            The original gene nomenclature has been retained. Genes presumably
            inherited from the common ancestor of alpha-, beta- and
            gammaherpesviruses (core genes), from the common ancestor of beta-
            and gammaherpesviruses (betagamma genes), or from the common
            ancestor of betaherpesviruses (beta genes) are indicated. A
            standard protein nomenclature has been applied so that orthologs
            have the same name in all herpesviruses.
FEATURES             Qualifiers
     source          /organism="Human betaherpesvirus 5"
                     /mol_type="genomic DNA"
                     /strain="3157"
                     /isolation_source="urine from a congenitally infected
                     infant"
                     /host="Homo sapiens"
                     /db_xref="taxon:10359"
                     /country="United Kingdom"
                     /collection_date="2001"
                     /note="sequenced at passage 3 in human fibroblasts; three
                     genes are mutated (RL13, UL40 and UL128);
                     acronym: HCMV; acronym: HHV-5"
     protein         /gene="UL80"
                     /EC_number="3.4.21.97"
                     /note="serine protease (N-terminal region); minor scaffold
                     protein (remainder of protein, clipped near C terminus);
                     involved in capsid morphogenesis"
BEGIN
        1 MTMDEQQPQA VAPVYVGGFL ARYDQSPDEA ELLLPRDVVE HWLHAQGQGQ PSLSVALPLN
       61 INHDDTAVVG HVAAMQSVRD GLFCLGCVTS PRFLEIVRRA SEKSELVSRG PVSPLQPDKV
      121 VEFLSGSYAG LSLSSRRCDD VEAATSLSGS ETTPFKHVAL CSVGRRRGTL AVYGRDPEWV
      181 TQRFPDLTAA DRDGLRAQWQ RCGSTVVDAS GDPFRSDSYG LLGNSVDALY IRERLPKLRY
      241 DKQLVGVTER ESYVKASVSP EAACDIKAAS AERSGDSRSQ AATPAAGARV PSSSPSLPVE
      301 PPSPVQPPAL PASPSVLPAE SPPSLSPSEP AEAASMSHPL SAAVPAATAP PGATVAGASP
      361 AVPSLAWPHD GVYLPKDAFF SLLGASRSAA PVMYPGAVAA PPSASPAPLP LPSYPAPYGA
      421 PVVGYDQLAA RHFAEYVDPH YPGWSRRYEP APPLHSACPV PPPPSPAYYR RRDSPGGMDE
      481 PPSGWERYDG GHRGQSQKQH RHGGSGGHNK RRKEAAAASS SSSDEDLSFP GEAEHGRARK
      541 RLKSHVNSDG GSGGHAGSNQ QQQQRYDELR DAIHELKRDL FAARQSSTLL SAALPAAASS
      601 SPTTTTVCTP TGELTSGGGE TPTALLSGGA KVAERAQAGV VNASCRLATA SGSETATAGP
      661 STAGSSSCPA SVVLAAAAAQ AAAASQSPPK DMVDLNRRIF VAALNKLE
//