LOCUS ACS93406.1 472 aa PRT VRL 09-MAY-2013
DEFINITION Human betaherpesvirus 5 envelope glycoprotein O protein.
ACCESSION GQ221974-69
PROTEIN_ID ACS93406.1
SOURCE Human betaherpesvirus 5 (HHV-5)
ORGANISM Human betaherpesvirus 5
Viruses; Duplodnaviria; Heunggongvirae; Peploviricota;
Herviviricetes; Herpesvirales; Orthoherpesviridae;
Betaherpesvirinae; Cytomegalovirus; Cytomegalovirus humanbeta5.
REFERENCE 1 (bases 1 to 235154)
AUTHORS Davison,A.J., Akter,P., Cunningham,C., Dolan,A., Addison,C.,
Dargan,D.J., Hassan-Walker,A.F., Emery,V.C., Griffiths,P.D. and
Wilkinson,G.W.
TITLE Homology between the human cytomegalovirus RL11 gene family and
human adenovirus E3 genes
JOURNAL J. Gen. Virol. 84 (PT 3), 657-663 (2003)
PUBMED 12604818
REFERENCE 2 (bases 1 to 235154)
AUTHORS Akter,P., Cunningham,C., McSharry,B.P., Dolan,A., Addison,C.,
Dargan,D.J., Hassan-Walker,A.F., Emery,V.C., Griffiths,P.D.,
Wilkinson,G.W. and Davison,A.J.
TITLE Two novel spliced genes in human cytomegalovirus
JOURNAL J. Gen. Virol. 84 (PT 5), 1117-1122 (2003)
PUBMED 12692276
REFERENCE 3 (bases 1 to 235154)
AUTHORS Dolan,A., Cunningham,C., Hector,R.D., Hassan-Walker,A.F., Lee,L.,
Addison,C., Dargan,D.J., McGeoch,D.J., Gatherer,D., Emery,V.C.,
Griffiths,P.D., Sinzger,C., McSharry,B.P., Wilkinson,G.W. and
Davison,A.J.
TITLE Genetic content of wild-type human cytomegalovirus
JOURNAL J. Gen. Virol. 85 (PT 5), 1301-1312 (2004)
PUBMED 15105547
REFERENCE 4 (bases 1 to 235154)
AUTHORS Griffin,C., Wang,E.C., McSharry,B.P., Rickards,C., Browne,H.,
Wilkinson,G.W. and Tomasec,P.
TITLE Characterization of a highly glycosylated form of the human
cytomegalovirus HLA class I homologue gpUL18
JOURNAL J. Gen. Virol. 86 (PT 11), 2999-3008 (2005)
PUBMED 16227221
REFERENCE 5 (bases 1 to 235154)
AUTHORS Cunningham,C., Gatherer,D., Hilfrich,B., Baluchova,K., Dargan,D.J.,
Thomson,M., Griffiths,P.D., Wilkinson,G.W., Schulz,T.F. and
Davison,A.J.
TITLE Sequences of complete human cytomegalovirus genomes from infected
cell cultures and clinical specimens
JOURNAL J. Gen. Virol. 91 (PT 3), 605-615 (2010)
PUBMED 19906940
REFERENCE 6 (bases 1 to 235154)
AUTHORS Davison,A.J.
TITLE Direct Submission
JOURNAL Submitted (28-MAY-2009) MRC Virology Unit, Church Street, Glasgow
G11 5JR, UK
COMMENT On or before Aug 17, 2009 this sequence version replaced
AY446863.1, AY446867.1, AY446875.1, AY169795.2, AY156040.1,
AY325311.1, DQ195526.1.
The original gene nomenclature has been retained. Genes presumably
inherited from the common ancestor of alpha-, beta- and
gammaherpesviruses (core genes), from the common ancestor of beta-
and gammaherpesviruses (betagamma genes), or from the common
ancestor of betaherpesviruses (beta genes) are indicated. A
standard protein nomenclature has been applied so that orthologs
have the same name in all herpesviruses.
FEATURES Qualifiers
source /organism="Human betaherpesvirus 5"
/mol_type="genomic DNA"
/strain="3157"
/isolation_source="urine from a congenitally infected
infant"
/host="Homo sapiens"
/db_xref="taxon:10359"
/country="United Kingdom"
/collection_date="2001"
/note="sequenced at passage 3 in human fibroblasts; three
genes are mutated (RL13, UL40 and UL128);
acronym: HCMV; acronym: HHV-5"
protein /gene="UL74"
/note="contains signal peptide; associated with envelope
glycoprotein H and envelope glycoprotein L; involved in
virion morphogenesis"
BEGIN
1 MGKKEMIMVK GIPKIMLLIS ITFLLLSLIN CNVLVNSRGT RRSWPYTVLS YRGKEILKKQ
61 KEDILKRLMS TSSDGYRFLM YPSQQKFHAI VISMDKFPQD YILAGPIRND SITHMWFDFY
121 STQLRKPAKY VYSEYNHTAH KITLRPPPCG TVPSMNCLSE MLNVSKRNDT GEKGCGNFTT
181 FNPMFFNVPR WNTKLYIGSN KVNVDSQTIY FLGLTALLLR YAQRNCTRSF YLVNAMSRNL
241 FRVPKYINGT KLKNTMRKLK RKQALVKEQP QKKNKKSQST TTPYLSYTTS TAFNVTTNVT
301 YSATAAVTRV ATSTTGYRPD SNFMKSIMAT QLRDLATWVY TTLRYRNEPF CKPDRNRTAV
361 SEFMKNTHVL IRNETPYTIY GTLDMSSLYY NETMSVENET ASDNNETTPT SPSTRFQRTF
421 IDPLWDYLDS LLFLDKIRNF SLQLPAYGNL TPPEHRRAAN LSTLNSLWWW SQ
//