LOCUS ACM58118.1 836 aa PRT BCT 01-MAR-2021 DEFINITION Halorubrum lacusprofundi ATCC 49239 ERCC4 domain protein protein. ACCESSION CP001365-2512 PROTEIN_ID ACM58118.1 SOURCE Halorubrum lacusprofundi ATCC 49239 ORGANISM Halorubrum lacusprofundi ATCC 49239 Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales; Haloferacaceae; Halorubrum. REFERENCE 1 (bases 1 to 2735295) AUTHORS Dassarma,S., Capes,M.D., Karan,R. and Dassarma,P. TITLE Amino acid substitutions in cold-adapted proteins from Halorubrum lacusprofundi, an extremely halophilic microbe from antarctica JOURNAL PLoS One 8 (3), e58587 (2013) PUBMED 23536799 REFERENCE 2 (bases 1 to 2735295) AUTHORS Karan,R., Capes,M.D., DasSarma,P. and DasSarma,S. TITLE Cloning, overexpression, purification, and characterization of a polyextremophilic beta-galactosidase from the Antarctic haloarchaeon Halorubrum lacusprofundi JOURNAL BMC Biotechnol 13, 3 (2013) PUBMED 23320757 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 2735295) AUTHORS Anderson,I.J., DasSarma,P., Lucas,S., Copeland,A., Lapidus,A., Del Rio,T.G., Tice,H., Dalin,E., Bruce,D.C., Goodwin,L., Pitluck,S., Sims,D., Brettin,T.S., Detter,J.C., Han,C.S., Larimer,F., Hauser,L., Land,M., Ivanova,N., Richardson,P., Cavicchioli,R., DasSarma,S., Woese,C.R. and Kyrpides,N.C. TITLE Complete genome sequence of the Antarctic Halorubrum lacusprofundi type strain ACAM 34 JOURNAL Stand Genomic Sci 11 (1), 70 (2016) PUBMED 27617060 REMARK Publication Status: Online-Only REFERENCE 4 (bases 1 to 2735295) AUTHORS Laye,V.J., Karan,R., Kim,J.M., Pecher,W.T., DasSarma,P. and DasSarma,S. TITLE Key amino acid residues conferring enhanced enzyme activity at cold temperatures in an Antarctic polyextremophilic beta-galactosidase JOURNAL Proc Natl Acad Sci U S A 114 (47), 12530-12535 (2017) PUBMED 29109294 REFERENCE 5 (bases 1 to 2735295) AUTHORS Laye,V.J. and DasSarma,S. TITLE An Antarctic Extreme Halophile and Its Polyextremophilic Enzyme: Effects of Perchlorate Salts JOURNAL Astrobiology 18 (4), 412-418 (2018) PUBMED 29189043 REFERENCE 6 (bases 1 to 2735295) AUTHORS DasSarma,S., DasSarma,P., Laye,V.J. and Schwieterman,E.W. TITLE Extremophilic models for astrobiology: haloarchaeal survival strategies and pigments for remote sensing JOURNAL Extremophiles 24 (1), 31-41 (2020) PUBMED 31463573 REFERENCE 7 (bases 1 to 2735295) AUTHORS Lucas,S., Copeland,A., Lapidus,A., Glavina del Rio,T., Dalin,E., Tice,H., Bruce,D., Goodwin,L., Pitluck,S., Sims,D., Brettin,T., Detter,J.C., Han,C., Larimer,F., Land,M., Hauser,L., Kyrpides,N., Ivanova,N., Anderson,I., DasSarma,S., Cavicchioli,R. and Richardson,P. CONSRTM US DOE Joint Genome Institute TITLE Direct Submission JOURNAL Submitted (14-JAN-2009) US DOE Joint Genome Institute, 2800 Mitchell Drive B310, Walnut Creek, CA 94598-1698, USA COMMENT URL -- http://www.jgi.doe.gov JGI Project ID: 4001421 Source DNA available from Professor Shiladitya DasSarma Archaea available from ATCC: ATCC 49239 Contacts: Ricardo Cavicchioli (r.cavicchioli@unsw.edu.au) Shiladitya DasSarma (sdassarma@som.umaryland.edu) David Bruce (microbe@cuba.jgi-psf.org) Annotation done by JGI-ORNL and JGI-PGF Finishing done by JGI-LANL Finished microbial genomes have been curated to close all gaps with greater than 98% coverage of at least two independent clones. Each base pair has a minimum q (quality) value of 30 and the total error rate is less than one per 50000. The JGI and collaborators endorse the principles for the distribution and use of large scale sequencing data adopted by the larger genome sequencing community and urge users of this data to follow them. it is our intention to publish the work of this project in a timely fashion and we welcome collaborative interaction on the project and analysis. (http://www.genome.gov/page.cfm?pageID=10506376). FEATURES Qualifiers source /organism="Halorubrum lacusprofundi ATCC 49239" /mol_type="genomic DNA" /strain="ATCC 49239" /culture_collection="ATCC:49239" /type_material="type strain of Halorubrum lacusprofundi" /db_xref="taxon:416348" /chromosome="1" protein /locus_tag="Hlac_2546" /inference="protein motif:PFAM:PF02732" /note="PFAM: helix-hairpin-helix motif; helicase domain protein; ERCC4 domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: Helix-hairpin-helix DNA-binding class 1; DEAD-like helicases; KEGG: hma:rrnAC2704 Hef nuclease" /transl_table=11 /db_xref="InterPro:IPR000445" /db_xref="InterPro:IPR001650" /db_xref="InterPro:IPR003583" /db_xref="InterPro:IPR006166" /db_xref="InterPro:IPR006935" /db_xref="InterPro:IPR011545" /db_xref="InterPro:IPR014001" /db_xref="InterPro:IPR014021" BEGIN 1 MATEATGIDR PLLVDDFLQR RRYQLQLADA AADEHTLVCL PTGLGKTTVS LLVTAERLHE 61 VGGKALFLAP TKPLVQQHAD FYREALSIPD DEIVVFTGDV KPDDRAALWN DARIVIATPQ 121 VVENDLVGNR ISLRDVTHCT FDECHRATGD YAYVYIAERY HADAADPLVT GMSASPGGDT 181 EEIETVCENL GLSNVEVMTE EDADVDEYTH DTDVQWEQVT LPDEVIAIRD ALNEVITDRL 241 EKLKSLGVTN KTSPDLSQRD LNEMRGKLKK MMDNDQSDGY KGMSTHAEVM KLRRATELVE 301 TQSVESVRRY FERQREAARS SGASKASQRM VADPKVREAM RKAEAFDGLH PKFSKARILL 361 AETLGINEGE RAILFTESRD TAEALVEFLS TSFDVRKFVG QGDKEGSDGM SQKQQQETLD 421 EFKAGDFEVL VSTSVAEEGL DVPEVDLVCF YEPVPTAIRS IQRKGRTGRQ AEGKVVVLMA 481 EDTRDEAFFW ISRRREKKMA SQLAELKEAT DDIEETVDDG QAGLDAFAGG SAGNDTKPEA 541 DNSAADSDDG GDDDNTDAGL TDFAAEARDG DADGEDNDDD GGDESDGGDE SEGDSDDAGE 601 VEASEGDSDD AGVVATAGVD EGVEVVVDQR ELDSTIAKDL STRDGLVTRL ETLAVGDYVL 661 SDRVAVERKS AADFVDSMLD SDRSMFEQVG ELSRAYARPV MVVEGTNLYG QRDIDPNAIR 721 GALASLAVDF DVSVLRTEGE SDTTELLATI AKREQETRDR EVSVHGEKTA KTRAEQQEYV 781 VSSIADIGPV TARTLLEHFG TVEAVMTAPE DDLLEVDGVG PVTAERIREV VGSEYE //