LOCUS AAR31539.2 683 aa PRT VRL 09-MAY-2013
DEFINITION Human betaherpesvirus 5 protein UL112 protein.
ACCESSION GQ221974-101
PROTEIN_ID AAR31539.2
SOURCE Human betaherpesvirus 5 (HHV-5)
ORGANISM Human betaherpesvirus 5
Viruses; Duplodnaviria; Heunggongvirae; Peploviricota;
Herviviricetes; Herpesvirales; Orthoherpesviridae;
Betaherpesvirinae; Cytomegalovirus; Cytomegalovirus humanbeta5.
REFERENCE 1 (bases 1 to 235154)
AUTHORS Davison,A.J., Akter,P., Cunningham,C., Dolan,A., Addison,C.,
Dargan,D.J., Hassan-Walker,A.F., Emery,V.C., Griffiths,P.D. and
Wilkinson,G.W.
TITLE Homology between the human cytomegalovirus RL11 gene family and
human adenovirus E3 genes
JOURNAL J. Gen. Virol. 84 (PT 3), 657-663 (2003)
PUBMED 12604818
REFERENCE 2 (bases 1 to 235154)
AUTHORS Akter,P., Cunningham,C., McSharry,B.P., Dolan,A., Addison,C.,
Dargan,D.J., Hassan-Walker,A.F., Emery,V.C., Griffiths,P.D.,
Wilkinson,G.W. and Davison,A.J.
TITLE Two novel spliced genes in human cytomegalovirus
JOURNAL J. Gen. Virol. 84 (PT 5), 1117-1122 (2003)
PUBMED 12692276
REFERENCE 3 (bases 1 to 235154)
AUTHORS Dolan,A., Cunningham,C., Hector,R.D., Hassan-Walker,A.F., Lee,L.,
Addison,C., Dargan,D.J., McGeoch,D.J., Gatherer,D., Emery,V.C.,
Griffiths,P.D., Sinzger,C., McSharry,B.P., Wilkinson,G.W. and
Davison,A.J.
TITLE Genetic content of wild-type human cytomegalovirus
JOURNAL J. Gen. Virol. 85 (PT 5), 1301-1312 (2004)
PUBMED 15105547
REFERENCE 4 (bases 1 to 235154)
AUTHORS Griffin,C., Wang,E.C., McSharry,B.P., Rickards,C., Browne,H.,
Wilkinson,G.W. and Tomasec,P.
TITLE Characterization of a highly glycosylated form of the human
cytomegalovirus HLA class I homologue gpUL18
JOURNAL J. Gen. Virol. 86 (PT 11), 2999-3008 (2005)
PUBMED 16227221
REFERENCE 5 (bases 1 to 235154)
AUTHORS Cunningham,C., Gatherer,D., Hilfrich,B., Baluchova,K., Dargan,D.J.,
Thomson,M., Griffiths,P.D., Wilkinson,G.W., Schulz,T.F. and
Davison,A.J.
TITLE Sequences of complete human cytomegalovirus genomes from infected
cell cultures and clinical specimens
JOURNAL J. Gen. Virol. 91 (PT 3), 605-615 (2010)
PUBMED 19906940
REFERENCE 6 (bases 1 to 235154)
AUTHORS Davison,A.J.
TITLE Direct Submission
JOURNAL Submitted (28-MAY-2009) MRC Virology Unit, Church Street, Glasgow
G11 5JR, UK
COMMENT On or before Aug 17, 2009 this sequence version replaced
AY446863.1, AY446867.1, AY446875.1, AY169795.2, AY156040.1,
AY325311.1, DQ195526.1.
The original gene nomenclature has been retained. Genes presumably
inherited from the common ancestor of alpha-, beta- and
gammaherpesviruses (core genes), from the common ancestor of beta-
and gammaherpesviruses (betagamma genes), or from the common
ancestor of betaherpesviruses (beta genes) are indicated. A
standard protein nomenclature has been applied so that orthologs
have the same name in all herpesviruses.
FEATURES Qualifiers
source /organism="Human betaherpesvirus 5"
/mol_type="genomic DNA"
/strain="3157"
/isolation_source="urine from a congenitally infected
infant"
/host="Homo sapiens"
/db_xref="taxon:10359"
/country="United Kingdom"
/collection_date="2001"
/note="sequenced at passage 3 in human fibroblasts; three
genes are mutated (RL13, UL40 and UL128);
acronym: HCMV; acronym: HHV-5"
protein /gene="UL112"
/note="involved in gene regulation; involved in DNA
replication"
intron_pos 253:1 (1/1)
BEGIN
1 MDLPTTVVRK YWTFANPNRI LHQSVNQTFD VRQFVFDTAR LVNCVDGDGK VLHLNKGWLC
61 ATIMQHGEAS AGAKTQQGFM SIDITGDGEL QEHLFVRGGI VFNKSVSSVV GSSGPNESAL
121 LTMISENGNL QVTYVRHYLK NHGESSGGGG GCGAASTASA VCVSSLGGSG GTRDGPSAEE
181 QQRRRQEQRH EERRKKSSSS AGGGGGGGAG GGGGGGGSGG QHSSDSANGL LRDPRLMNRQ
241 KERRPPPSSE NDGSPPLREA KRQKTTAQHE GHGGGGKNET EQQSGGAGGG GGGGSGRMSL
301 PLDTSEAVAF LNYSSSSSAV SSSSNNHHHH HHHHNAVTDV AAGTDGALLL PIERGAVVSS
361 PSSPSSLLSL PRPSSAHSAG ETVQESEAAA TAAAAGLMMM RRMRRAPAEA AEAPPQSEEE
421 NDSTTPVSNC RVPPNSQESA APQPPRSPRF DDIIQSLTKM LNDCKEKRLC DLPLVSSRLL
481 PETSGGTVVV NHSSVARTAA AVSTAGVGPP AAACPPLVTT GVVPSGSVAG VAPVAAAVET
541 PAAPPRPVCE IKPYVVNPVV ATAAAASNSS SSSSAPLPPP PPPPPGGRRG RARNNTRGGG
601 GGGGGRNSRR QAASSSSSSS RRSRRRNNRH EDEEDNDPLL RLSQVAGSGR RRGPSFLEDG
661 LEIIDPSEEA AIAAASIAAF FDD
//