LOCUS AAR31533.2 684 aa PRT VRL 12-OCT-2016
DEFINITION Human betaherpesvirus 5 protein UL112 protein.
ACCESSION GU937742-101
PROTEIN_ID AAR31533.2
SOURCE Human betaherpesvirus 5 (HHV-5)
ORGANISM Human betaherpesvirus 5
Viruses; Duplodnaviria; Heunggongvirae; Peploviricota;
Herviviricetes; Herpesvirales; Orthoherpesviridae;
Betaherpesvirinae; Cytomegalovirus; Cytomegalovirus humanbeta5.
REFERENCE 1 (bases 1 to 235404)
AUTHORS Davison,A.J., Akter,P., Cunningham,C., Dolan,A., Addison,C.,
Dargan,D.J., Hassan-Walker,A.F., Emery,V.C., Griffiths,P.D. and
Wilkinson,G.W.
TITLE Homology between the human cytomegalovirus RL11 gene family and
human adenovirus E3 genes
JOURNAL J. Gen. Virol. 84 (PT 3), 657-663 (2003)
PUBMED 12604818
REFERENCE 2 (bases 1 to 235404)
AUTHORS Akter,P., Cunningham,C., McSharry,B.P., Dolan,A., Addison,C.,
Dargan,D.J., Hassan-Walker,A.F., Emery,V.C., Griffiths,P.D.,
Wilkinson,G.W. and Davison,A.J.
TITLE Two novel spliced genes in human cytomegalovirus
JOURNAL J. Gen. Virol. 84 (PT 5), 1117-1122 (2003)
PUBMED 12692276
REFERENCE 3 (bases 1 to 235404)
AUTHORS Dolan,A., Cunningham,C., Hector,R.D., Hassan-Walker,A.F., Lee,L.,
Addison,C., Dargan,D.J., McGeoch,D.J., Gatherer,D., Emery,V.C.,
Griffiths,P.D., Sinzger,C., McSharry,B.P., Wilkinson,G.W. and
Davison,A.J.
TITLE Genetic content of wild-type human cytomegalovirus
JOURNAL J. Gen. Virol. 85 (PT 5), 1301-1312 (2004)
PUBMED 15105547
REFERENCE 4 (bases 1 to 235404)
AUTHORS Davison,A.J.
TITLE Human cytomegalovirus RL11 gene family: variation, recombination
and transcription
JOURNAL Unpublished
REFERENCE 5 (bases 1 to 235404)
AUTHORS Davison,A.J.
TITLE Direct Submission
JOURNAL Submitted (26-FEB-2010) MRC Virology Unit, Church Street, Glasgow
G11 5JR, UK
REFERENCE 6 (bases 1 to 235404)
AUTHORS Davison,A.J.
TITLE Direct Submission
JOURNAL Submitted (12-OCT-2016) MRC Virology Unit, Church Street, Glasgow
G11 5JR, UK
REMARK Sequence update by submitter
COMMENT On Oct 12, 2016 this sequence version replaced GU937742.1.
The original gene nomenclature has been retained. Genes presumably
inherited from the common ancestor of alpha-, beta- and
gammaherpesviruses (core genes), from the common ancestor of beta-
and gammaherpesviruses (betagamma genes), or from the common
ancestor of betaherpesviruses (beta genes) are indicated. A
standard protein nomenclature has been applied so that orthologs
have the same name in all herpesviruses.
FEATURES Qualifiers
source /organism="Human betaherpesvirus 5"
/mol_type="genomic DNA"
/strain="Toledo"
/isolation_source="urine from a congenitally infected
infant"
/host="Homo sapiens"
/db_xref="taxon:10359"
/country="USA"
/collection_date="1984"
/note="passaged several times in human fibroblasts;
contains inversion of 14336 bp region (genes UL128 to
UL133); 3 genes are mutated (RL13, UL9 and UL128);
acronym: HCMV; acronym: HHV-5"
protein /gene="UL112"
/note="involved in gene regulation; involved in DNA
replication"
intron_pos 253:1 (1/1)
BEGIN
1 MDLPTTVVRK YWTFANPNRI LHQSVNQTFD VRQFVFDTAR LVNCVDGDGK VLHLNKGWLC
61 ATIMQHGEAS AGAKTQQGFM SIDITGDGEL QEHLFVRGGI VFNKSVSSVV GSSGPNESAL
121 LTMISENGNL QVTYVRHYLK NHGESSSGGG GCGAASTASA VCVSSLGGSG GTRDGPSAEE
181 QQRRRQEQRH EERRKKSSSS AGGGGGGGAG GGGGGGGSGG QHSSDSANGL LRDPRLMNRQ
241 KERRPPPSSE NDGSPPLREA KRQKTTAQHE GHGGGGKNET EQQSGGAGGG GGGGSGRMSL
301 PLDTSEAVAF LNYSSSSSAV SSSSNNHHHH HHHHNAVTDV AAGTDGALLL PIERGAVVSS
361 PSSTSPSSLL SLPRPGSAHS AGETVQESEA AATAAAAGLM MMRRMRRAPA EAAEAPPQSE
421 EENDSTTPVS NCRVPPNSQE SAAPQPPRSP RFDDIIQSLT KMLNDCKEKR LCDLPLVSSR
481 LLPETSGGTV VVNHSSVART AAAVSTAGVG PPAAACPPLV TTGVVPSGSV AGVAPVAAAV
541 ETPAAPPRPV CEIKPYVVNP VVATAAAASN SSSSSSAPLP PPPPPPGGRR GRARNNTRGG
601 GGGGGGRNSR RQAASSSSSS SRRSRRRNNR HEDEEDNDPL LRLSQVAGSG RRRGPSFLED
661 GLEIIDPSEE AAIAAASIAA FFDD
//