LOCUS       AAL18966.1               820 aa    PRT              BCT 24-JUL-2018
DEFINITION  Salmonella enterica subsp. enterica serovar Typhimurium
            str. LT2 aspartokinase I protein.
ACCESSION   AE006468-2
PROTEIN_ID  AAL18966.1
SOURCE      Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4857450)
  AUTHORS   McClelland,M., Sanderson,K.E., Spieth,J., Clifton,S.W.,
            Latreille,P., Courtney,L., Porwollik,S., Ali,J., Dante,M., Du,F.,
            Hou,S., Layman,D., Leonard,S., Nguyen,C., Scott,K., Holmes,A.,
            Grewal,N., Mulvaney,E., Ryan,E., Sun,H., Florea,L., Miller,W.,
            Stoneking,T., Nhan,M., Waterston,R. and Wilson,R.K.
  TITLE     Complete genome sequence of Salmonella enterica serovar Typhimurium
            LT2
  JOURNAL   Nature 413 (6858), 852-856 (2001)
   PUBMED   11677609
REFERENCE   2  (bases 1 to 4857450)
  CONSRTM   The Salmonella typhimurium Genome Sequencing Project
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2001) Genome Sequencing Center, Department of
            Genetics, Washington University School of Medicine, 4444 Forest
            Park Boulevard, St. Louis, MO 63108, USA
REFERENCE   3  (bases 1 to 4857450)
  AUTHORS   McClelland,M., Jain,A., Saraogi,P., Mendelson,R., Westerman,R.,
            SanMiguel,P. and Csonka,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2016) Department of Microbiology and Molecular
            Genetics, University of California, Irvine, CA 92697, USA
  REMARK    Sequence update by submitter
COMMENT     On Jan 13, 2016 this sequence version replaced AE006468.1.
            Supported by NIH grant 5U 01 AI43283
            
            Coding sequences below are predicted from manually evaluated
            computer analysis, using similarity information and the programs;
            GLIMMER; http://www.tigr.org/softlab/glimmer/glimmer.html and
            GeneMark; http://opal.biology.gatech.edu/GeneMark/
            
            EC numbers were kindly provided by Junko Yabuzaki and the Kyoto
            Encyclopedia of Genes and Genomes; http://www.genome.ad.jp/kegg/,
            and Pedro Romero and Peter Karp at EcoCyc;
            http://ecocyc.PangeaSystems.com/ecocyc/
            
            The analyses of ribosome binding sites and promoter binding sites
            were kindly provided by Heladia Salgado, Julio Collado-Vides and
            ReguonDB;
            http://kinich.cifn.unam.mx:8850/db/regulondb_intro.frameset
            
            This sequence was finished as follows unless otherwise noted: all
            regions were double stranded, sequenced with an alternate
            chemistries or covered by high quality data (i.e., phred quality >=
            30); an attempt was made to resolve all sequencing problems, such
            as compressions and repeats; all regions were covered by sequence
            from more than one m13 subclone.
FEATURES             Qualifiers
     source          /organism="Salmonella enterica subsp. enterica serovar
                     Typhimurium str. LT2"
                     /mol_type="genomic DNA"
                     /strain="LT2"
                     /serovar="Typhimurium"
                     /sub_species="enterica"
                     /culture_collection="ATCC:700720"
                     /culture_collection="SGSC:1412"
                     /type_material="type strain of Salmonella enterica"
                     /db_xref="taxon:99287"
                     /focus
     source          /organism="Salmonella phage Fels-1"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:128975"
     source          /organism="Phage Gifsy-2"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:129862"
     source          /organism="Phage Gifsy-1"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:129861"
     source          /organism="Salmonella virus Fels2"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:194701"
     protein         /gene="thrA"
                     /locus_tag="STM0002"
                     /EC_number="1.1.1.3"
                     /EC_number="2.7.2.4"
                     /note="bifunctional; N-terminaus is aspartokinase I and C
                     terminus is homoserine dehydrogenase I; similar to E. coli
                     aspartokinase I, homoserine dehydrogenase I (AAC73113.1);
                     Blastp hit to AAC73113.1 (820 aa), 94% identity in aa 1 -
                     820"
                     /transl_table=11
BEGIN
        1 MRVLKFGGTS VANAERFLRV ADILESNARQ GQVATVLSAP AKITNHLVAM IEKTIGGQDA
       61 LPNISDAERI FSDLLAGLAS AQPGFPLARL KMVVEQEFAQ IKHVLHGISL LGQCPDSINA
      121 ALICRGEKMS IAIMAGLLEA RGHRVTVIDP VEKLLAVGHY LESTVDIAES TRRIAASQIP
      181 ADHMILMAGF TAGNEKGELV VLGRNGSDYS AAVLAACLRA DCCEIWTDVD GVYTCDPRQV
      241 PDARLLKSMS YQEAMELSYF GAKVLHPRTI TPIAQFQIPC LIKNTGNPQA PGTLIGASSD
      301 DDNLPVKGIS NLNNMAMFSV SGPGMKGMIG MAARVFAAMS RAGISVVLIT QSSSEYSISF
      361 CVPQSDCARA RRAMQDEFYL ELKEGLLEPL AVTERLAIIS VVGDGMRTLR GISAKFFAAL
      421 ARANINIVAI AQGSSERSIS VVVNNDDATT GVRVTHQMLF NTDQVIEVFV IGVGGVGGAL
      481 LEQLKRQQTW LKNKHIDLRV CGVANSKALL TNVHGLNLDN WQAELAQANA PFNLGRLIRL
      541 VKEYHLLNPV IVDCTSSQAV ADQYADFLRE GFHVVTPNKK ANTSSMDYYH QLRFAAAQSR
      601 RKFLYDTNVG AGLPVIENLQ NLLNAGDELQ KFSGILSGSL SFIFGKLEEG MSLSQATALA
      661 REMGYTEPDP RDDLSGMDVA RKLLILARET GRELELSDIV IEPVLPNEFD ASGDVTAFMA
      721 HLPQLDDAFA ARVAKARDEG KVLRYVGNIE EDGVCRVKIA EVDGNDPLFK VKNGENALAF
      781 YSHYYQPLPL VLRGYGAGND VTAAGVFADL LRTLSWKLGV
//