LOCUS AAL09459.1 5938 aa PRT HUM 19-DEC-2001
DEFINITION Homo sapiens macrophin 1 isoform 4 protein.
ACCESSION AF317696-1
PROTEIN_ID AAL09459.1
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 19153)
AUTHORS Gong,T.W., Besirli,C.G. and Lomax,M.I.
TITLE MACF1 gene structure: a hybrid of plectin and dystrophin
JOURNAL Mamm. Genome 12 (11), 852-861 (2001)
PUBMED 11845288
REFERENCE 2 (bases 1 to 19153)
AUTHORS Gong,T.-W.L. and Lomax,M.I.
TITLE Direct Submission
JOURNAL Submitted (31-OCT-2000) Kresge Hearing Research Institute,
Department of Otolarynology/Head-Neck Surgery, University of
Michigan, 9301E MSRBIII, 1150 W. Medical Center Dr., Ann Arbor, MI
48109-0648, USA
FEATURES Qualifiers
source /db_xref="H-InvDB:HIT000077229"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p32"
protein /gene="MACF1"
/note="MACF1-4; cytoskeletal protein"
BEGIN
1 MQKGLLDQDT GLVLLESQVI MSGLIAPETG ENLSLEEGIA RNLINPQMYQ QLRELQDALA
61 LISRLTESRG PLSVVEAIEK RIISETVGLK ILEAHLATGG FSLSPSENCI NLEEAFHQGL
121 ISAWLHSVLE SYLRTSKNLI DPNTAEKIGL LDLMQRCIVH QESGFKLLPV KQLAGGMVSL
181 KSGRKVSIFR AVQEGLIDRQ VTVRLLEAQL FAGGIVDPRT GHRLTVEEAV RHNLIDQDMA
241 CAILIRQLQT GGIIDTVTGQ RLTIDEAVSN DLVAAKIALV ILESLWSFMG LLWPESGEIL
301 PITDALEQGI VSTELAHKIL SNRQHIKALF LPATTEILSW KKAIESGILD RDLANNLKSI
361 CIPDVMPHMQ LADSAEQNIN PGAAVLPCSK SHPKATASQS ENLLFQLMTH SYINVQNGQR
421 LLLLDKELME TLTSRDEYQT SPPKVVEIGH QRQKTPEGLQ ESANVKISGT FSSGWTVRLP
481 EFQFSSQNKE YPDREDCTTE KGKKTTVETE DSSVENPEQD LFVEQKERNP NIDALKVINK
541 VKLEVQRQLI GTQREDQTAV SVRENASRGH LLTIPPAEAE GVPLVVDKDV FSVETPKKEH
601 QPLRNTSFTC QNEQAHTLET EYIHDETGGS HIKPQSKKLQ VQVKKTLGIK LELKSETDGN
661 VHPLDKKEML KKTFLAKDDH KESQEAQNIA GGSMMMSEKT DEEDSGREIF LSCSHPLELL
721 EEATLNVLSA QLLDGGIFHE QTGQKLLLNE AISRGIVPSH TAVKLMEKLN MFQGFFDSQT
781 CESLTTEEVI NEGLMDEKLL HNVLMADKAI SGVLDPRTQT LCSVKDAVTV GLLDKETATR
841 ILERQVVTGG IIDLKRGKKV SVTLASTLGL VDVADQPELI NLEKASKGRD AEKTVRERLI
901 SLQMETTGLI DPDSKAPLTV VQSIDRGLLE REEAVRLLTK QVVDGGIIHH ISGMRLSVDN
961 AFRHGLIGED LAEKLKRVEN LNIHQIFNPE TKENISLPKA IKLDLITSDL KREIQEVQAF
1021 TGNFVDLISG QRLTLAEAKK EGLLTNEAVL SPGMMHGIVD PENCRIVPYS ELVKKCKIDI
1081 ESGQRYLEVI PFSDIKDGVS DKVLTLSQAI QLGKVDFAST LKVLEAQANT GGIIDTATGK
1141 RLTLASALEE KLVDENMVRI IASHQVLNGG IVDIFSDQRV TLVEAIEKRL ISPELANMIQ
1201 IDSSEFSDHR AQIEKQEGIE VCALQNEFLG KDMLIACNQT AEMSCNKVEE SERLFQVENQ
1261 SAQEKVKVRV SDGEQAKKSR EISLKEFGCK DQRKPRMSSD AKEFISIINP HNLKGKSLGQ
1321 VSLTHPYSEC DFKLKEVARN NMGNDTNEEQ EKAVTKIEII SHMKQSTSCL DSEEIRENQG
1381 EVILEVQETY CETSGKLPSE QVLQQPMNAR VKSKREKREV IVEESIRTCK PAFLSEEKLY
1441 QETAIRDEHD SHIKSQPREM TSSEKGKEAD TEMGFSITFK IEESSSQVVP QGISVKHLDA
1501 LTLFSSKQAN EGKVNNLSLC LTLKPEENLS REIACGAQSE PFPCMTPRPE GLHYQESDGK
1561 AQVTGPSQIS KTDKSFQGTT RQETNYQDSW VTSKTKETKH QISSSNECKE KSYQEVSFDP
1621 ARGLKLEEIT VSRPDSKEVR YLEFSDRKDL HHQGSKSDDK LCGTLKSEIA TQELTGEKFL
1681 EMANPNVAGL EAGSIEDIVT QRGSRVLGSF LPEKLFKGVS QKENTGQQNA IISPTVLETS
1741 EEKTVSLTVC SAVKTEKTPQ EKLRESPGSE QTPFMTAPEG KGNGGVNPEP FRATQNVFTR
1801 QLCLEHDEKL VSYLSLLRNI EMRTKQIQPL ELNLAELQDL LCQAKVLERE LKDLTTLVSQ
1861 ELECVNQIII SQPQEVPAQL LKALEKDAKN LQKSLSSVSD TWNSRLLHFQ NAVEIEKTKV
1921 LNQHTQLEGR LQDLRAWVGN KNLILNSKGS NSEIDVDSLN LCLQQYEDLK QPMAERKAQL
1981 DALAFDIQFF ISEHAQDLSP QQNRQMLRLL NELQRSFQDI LEQTAAQVDA LQGHLQQMEQ
2041 EALVKTLQKQ QNTCHQQLED LCSWVGQAER ALAGHQGRTT QQDLSALQKN QSDLKDLQDD
2101 IQNRATSFAT VVKDIEGFME ENQTKLSPRE LTALREKLHQ AKEQYEALQE ETRVAQKELE
2161 EAVTSALQQE TEKSKAAKEL AENKKKIDAL LDWVTSVGSS GGQLLTNLPG MEQLSGASLE
2221 KGALDTTDGY MGVNQAPEKL DKQCEMMKAR HQELLSQQQN FILATQSAQA FLDQHGHNLT
2281 PEEQQMLQQK LGELKEQYST SLAQSEAELK QVQTLQDELQ KFLQDHKEFE SWLERSEKEL
2341 ENMHKGGSSP ETLPSLLKRQ GSFSEDVISH KGDLRFVTIS GQKVLDMENS FKEGKEPSEI
2401 GNLVKDKLKD ATERYTALHS KCTRLGSHLN MLLGQYHQFQ NSADSLQAWM QACEANVEKL
2461 LSDTVASDPG VLQEQLATTK QLQEELAEHQ VPVEKLQKVA RDIMEIEGEP APDHRHVQET
2521 TDSILSHFQS LSYSLAERSS LLQKAIAQSQ SVQESLESLL QSIGEVEQNL EGKQVSSLSS
2581 GVIQEALATN MKLKQDIARQ KSSLEATREM VTRFMETADS TTAAVLQGKL AEVSQRFEQL
2641 CLQQQEKESS LKKLLPQAEM FEHLSGKLQQ FMENKSRMLA SGNQPDQDIT HFFQQIQELN
2701 LEMEDQQENL DTLEHLVTEL SSCGFALDLC QHQDRVQNLR KDFTELQKTV KEREKDASSC
2761 QEQLDEFRKL VRTFQKWLKE TEGSIPPTET SMSAKELEKQ IEHLKSLLDD WASKGTLVEE
2821 INCKGTSLEN LIMEITAPDS QGKTGSILPS VGSSVGSVNG YHTCKDLTEI QCDMSDVNLK
2881 YEKLGGVLHE RQESLQAILN RMEEVHKEAN SVLQWLESKE EVLKSMDAMS SPTKTETVKA
2941 QAESNKAFLA ELEQNSPKIQ KVKEALAGLL VTYPNSQEAE NWKKIQEELN SRWERATEVT
3001 VARQRQLEES ASHLACFQAA ESQLRPWLME KELMMGVLGP LSIDPNMLNA QKQQVQFMLK
3061 EFEARRQQHE QLNEAAQGIL TGPGDVSLST SQVQKELQSI NQKWVELTDK LNSRSSQIDQ
3121 AIVKSTQYQE LLQDLSEKVR AVGQRLSVQS AISTQPEAVK QQLEETSEIR SDLEQLDHEV
3181 KEAQTLCDEL SVLIGEQYLK DELKKRLETV ALPLQGLEDL AADRINRLQA ALASTQQFQQ
3241 MFDELRTWLD DKQSQQAKNC PISAKLERLQ SQLQENEEFQ KSLNQHSGSY EVIVAEGESL
3301 LLSVPPGEEK RTLQNQLVEL KNHWEELSKK TADRQSRLKD CMQKAQKYQW HVEDLVPWIE
3361 DCKAKMSELR VTLDPVQLES SLLRSKAMLN EVEKRRSLLE ILNSAADILI NSSEADEDGI
3421 RDEKAGINQN MDAVTEELQA KTGSLEEMTQ RLREFQESFK NIEKKVEGAK HQLEIFDALG
3481 SQACSNKNLE KLRAQQEVLQ ALEPQVDYLR NFTQGLVEDA PDGSDASQLL HQAEVAQQEF
3541 LEVKQRVNSG CVMMENKLEG IGQFHCRVRE MFSQLADLDD ELDGMGAIGR DTDSLQSQIE
3601 DVRLFLNKIH VLKLDIEASE AECRHMLEEE GTLDLLGLKR ELEALNKQCG KLTERGKARQ
3661 EQLELTLGRV EDFYRKLKGL NDATTAAEEA EALQWVVGTE VEIINQQLAD FKMFQKEQVD
3721 PLQMKLQQVN GLGQGLIQSA GKDCDVQGLE HDMEEINARW NTLNKKVAQR IAQLQEALLH
3781 CGKFQDALEP LLSWLADTEE LIANQKPPSA EYKVVKAQIQ EQKLLQRLLD DRKATVDMLQ
3841 AEGGRIAQSA ELADREKITG QLESLESRWT ELLSKAAARQ KQLEDILVLA KQFHETAEPI
3901 SDFLSVTEKK LANSEPVGTQ TAKIQQQIIR HKALEEDIEN HATDVHQAVK IGQSLSSLTS
3961 PAEQGVLSEK IDSLQARYSE IQDRCCRKAA LLDQALSNAR LFGEDEVEVL NWLAEVEDKL
4021 SSVFVKDFKQ DVLHRQHADH LALNEEIVNR KKNVDQAIKN GQALLKQTTG EEVLLIQEKL
4081 DGIKTRYADI TVTSSKALRT LEQARQLATK FQSTYEELTG WLREVEEELA TSGGQSPTGE
4141 QIPQFQQRQK ELKKEVMEHR LVLDTVNEVS RALLELVPWR AREGLDKLVS DANEQYKLVS
4201 DTIGQRVDEI DAAIQRSQQY EQAADAELAW VAETKRKLMA LGPIRLEQDQ TTAQLQVQKA
4261 FSIDIIRHKD SMDELFSHRS EIFGTCGEEQ KTVLQEKTES LIQQYEAISL LNSERYARLE
4321 RAQVLVNQFW ETYEELSPWI EETRALIAQL PSPAIDHEQL RQQQEEMRQL RESIAEHKPH
4381 IDKLLKIGPQ LKELNPEEGE MVEEKYQKAE NMYAQIKEEV RQRALALDEA VSQSTQITEF
4441 HDKIEPMLET LENLSSRLRM PPLIPAEVDK IRECISDNKS ATVELEKLQP SFEALKRRGE
4501 ELIGRSQGAD KDLAAKEIQD KLDQMVFFWE DIKARAEERE IKFLDVLELA EKFWYDMAAL
4561 LTTIKDTQDI VHDLESPGID PSIIKQQVEA AETIKEETDG LHEELEFIRI LGADLIFACG
4621 ETEKPEVRKS IDEMNNAWEN LNKTWKERLE KLEDAMQAAV QYQDTLQAMF DWLDNTVIKL
4681 CTMPPVGTDL NTVKDQLNEM KEFKVEVYQQ QIEMEKLNHQ GELMLKKATD ETDRDIIREP
4741 LTELKHLWEN LGEKIAHRQH KLEGALLALG QFQHALEELM SWLTHTEELL DAQRPISGDP
4801 KVIEVELAKH HVLKNDVLAH QATVETVNKA GNELLESSAG DDASSLRSRL EAMNQCWESV
4861 LQKTEEREQQ LQSTLQQAQG FHSEIEDFLL ELTRMESQLS ASKPTGGLPE TAREQLDTHM
4921 ELYSQLKAKE ETYNQLLDKG RLMLLSRDDS GSGSKTEQSV ALLEQKWHVV SSKMEERKSK
4981 LEEALNLATE FQNSLQEFIN WLTLAEQSLN IASPPSLILN TVLSQIEEHK VFANEVNAHR
5041 DQIIELDQTG NQLKFLSQKQ DVVLIKNLLV SVQSRWEKVV QRSIERGRSL DDARKRAKQF
5101 HEAWKKLIDW LEDAESHLDS ELEISNDPDK IKLQLSKHKE FQKTLGGKQP VYDTTIRTGR
5161 ALKEKTLLPE DTQKLDNFLG EVRDKWDTVC GKSVERQHKL EEALLFSGQF MDALQALVDW
5221 LYKVEPQLAE DQPVHGDLDL VMNLMDAHKV FQKELGKRTG TVQVLKRSGR ELIENSRDDT
5281 TWVKGQLQEL STRWDTVCKL SVSKQSRLEQ ALKQAEVFRD TVHMLLEWLS EAEQTLRFRG
5341 ALPDDTEALQ SLIDTHKEFM KKVEEKRVDV NSAVAMGEVI LAVCHPDCIT TIKHWITIIR
5401 ARFEEVLTWA KQHQQRLETA LSELVANAEL LEELLAWIQW AETTLIQRDQ EPIPQNIDRV
5461 KALIAEHQTF MEEMTRKQPD VDRVTKTYKR KNIEPTHAPF IEKSRSGGRK SLSQPTPPPM
5521 PILSQSEAKN PRINQLSARW QQVWLLALER QRKLNDALDR LEELKEFANF DFDVWRKKYM
5581 RWMNHKKSRV MDFFRRIDKD QDGKITRQEF IDGILASKFP TTKLEMTAVA DIFDRDGDGY
5641 IDYYEFVAAL HPNKDAYRPT TDADKIEDEV TRQVAQCKCA KRFQVEQIGE NKYRFFLGNQ
5701 FGDSQQLRLV RILRSTVMVR VGGGWMALDE FLVKNDPCRA RGRTNIELRE KFILPEGASQ
5761 GMTPFRSRGR RSKPSSRAAS PTRSSSSASQ SNHSCTSMPS SPATPASGTK VIPSSGSKLK
5821 RPTPTFHSSR TSLAGDTSNS SSPASTGAKT NRADPKKSAS RPGSRAGSRA GSRASSRRGS
5881 DASDFDLLET QSACSDTSES SAAGGQGNSR RGLNKPSKIP TMSKKTTTAS PRTPGPKR
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