LOCUS AAI51838.1 3314 aa PRT HUM 10-JUN-2008
DEFINITION Homo sapiens MLL3 protein protein.
ACCESSION BC151837-1
PROTEIN_ID AAI51838.1
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 9944)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 9944)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (21-AUG-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Kazusa DNA Research Inst.
cDNA Library Preparation: Kazusa DNA Research Institute
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCF Plate: 10 Row: a Column: 2.
FEATURES Qualifiers
source /db_xref="H-InvDB:HIT000435962"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:8860136"
/tissue_type="Clones donated by Kazusa DNA Research Inst."
/clone_lib="Kazusa-KIAA-pBluescriptIISK+"
/lab_host="DH5alpha T1-resistant"
/note="Vector: pBluescript II SK+"
protein /gene="MLL3"
/gene_synonym="HALR"
/gene_synonym="KMT2C"
/db_xref="GeneID:58508"
/db_xref="HGNC:HGNC:13726"
/db_xref="MIM:606833"
BEGIN
1 VFSEQAANKD VNGQESTPGI VPDAVQVHTE EQQKSHPSES LDTDSLLIAV SSQHTVNTEL
61 EKQISNEVDS EDLKMSSEVK HICGEDQIED KMEVTENIEV VTHQITVQQE QLQLLEEPET
121 VVSREESRPP KLVMESVTLP LETLVSPHEE SISLCPEEQL VIERLQGEKE QKENSELSTG
181 LMDSEMTPTI EGCVKDVSYQ GGKSIKLSSE TESSFSSSAD ISKADVSSSP TPSSDLPSHD
241 MLHNYPSALS SSAGNIMPTT YISVTPKIGM GKPAITKRKF SPGRPRSKQG AWSTHNTVSP
301 PSWSPDISEG REIFKPRQLP GSAIWSIKVG RGSGFPGKRR PRGAGLSGRG GRGRSKLKSG
361 IGAVVLPGVS TADISSNKDD EENSMHNTVV LFSSSDKFTL NQDMCVVCGS FGQGAEGRLL
421 ACSQCGQCYH PYCVSIKITK VVLSKGWRCL ECTVCEACGK ATDPGRLLLC DDCDISYHTY
481 CLDPPLQTVP KGGWKCKWCV WCRHCGATSA GLRCEWQNNY TQCAPCASLS SCPVCYRNYR
541 EEDLILQCRQ CDRWMHAVCQ NLNTEEEVEN VADIGFDCSM CRPYMPASNV PSSDCCESSL
601 VAQIVTKVKE LDPPKTYTQD GVCLTESGMT QLQSLTVTVP RRKRSKPKLK LKIINQNSVA
661 VLQTPPDIQS EHSRDGEMDD SREGELMDCD GKSESSPERE AVDDETKGVE GTDGVKKRKR
721 KPYRPGIGGF MVRQRSRTGQ GKTKRSVIRK DSSGSISEQL PCRDDGWSEQ LPDTLVDESV
781 SVTESTEKIK KRYRKRKNKL EETFPAYLQE AFFGKDLLDT SRQSKISLDN LSEDGAQLLY
841 KTNMNTGFLD PSLDPLLSSS SAPTKSGTHG PADDPLADIS EVLNTDDDIL GIISDDLAKS
901 VDHSDIGPVT DDPSSLPQPN VNQSSRPLSE EQLDGILSPE LDKMVTDGAI LGKLYKIPEL
961 GGKDVEDLFT AVLSPANTQP TPLPQPPPPT QLLPIHNQDA FSRMPLMNGL IGSSPHLPHN
1021 SLPPGSGLGT FSAIAQSSYP DARDKNSAFN PMASDPNNSW TSSAPTVEGE NDTMSNAQRS
1081 TLKWEKEEAL GEMATVAPVL YTNINFPNLK EEFPDWTTRV KQIAKLWRKA SSQERAPYVQ
1141 KARDNRAALR INKVQMSNDS MKRQQQQDSI DPSSRIDSEL FKDPLKQRES EHEQEWKFRQ
1201 QMRQKSKQQA KIEATQKLEQ VKNEQQQQQQ QQFGSQHLLV QSGSDTPSSG IQSPLTPQPG
1261 NGNMSPAQSF HKELFTKQPP STPTSTSSDD VFVKPQAPPP PPAPSRIPIQ DSLSQAQTSQ
1321 PPSPQVFSPG SSNSRPPSPM DPYAKMVGTP RPPPVGHSFS RRNSAAPVEN CTPLSSVSRP
1381 LQMNETTANR PSPVRDLCSS STTNNDPYAK PPDTPRPVMT DQFPKSLGLS RSPVVSEQTA
1441 KGPIAAGTSD HFTKPSPRAD VFQRQRIPDS YARPLLTPAP LDSGPGPFKT PMQPPPSSQD
1501 PYGSVSQASR RLSVDPYERP ALTPRPIDNF SHNQSNDPYS QPPLTPHPAV NESFAHPSRA
1561 FSQPGTISRP TSQDPYSQPP GTPRPVVDSY SQSSGTARSN TDPYSQPPGT PRPTTVDPYS
1621 QQPQTPRPST QTDLFVTPVT NQRHSDPYAH PPGTPRPGIS VPYSQPPATP RPRISEGFTR
1681 SSMTRPVLMP NQDPFLQAAQ NRGPALPGPL VRPPDTCSQT PRPPGPGLSD TFSRVSPSAA
1741 RDPYDQSPMT PRSQSDSFGT SQTAHDVADQ PRPGSEGSFC ASSNSPMHSQ GQQFSGVSQL
1801 PGPVPTSGVT DTQNTVNMAQ ADTEKLRQRQ KLREIILQQQ QQKKIAGRQE KGSQDSPAVP
1861 HPGPLQHWQP ENVNQAFTRP PPPYPGNIRS PVAPPLGPRY AVFPKDQRGP YPPDVASMGM
1921 RPHGFRFGFP GGSHGTMPSQ ERFLVPPQQI QGSGVSPQLR RSVSVDMPRP LNNSQMNNPV
1981 GLPQHFSPQS LPVQQHNILG QAYIELRHRA PDGRQRLPFS APPGSVVEAS SNLRHGNFIP
2041 RPDFPGPRHT DPMRRPPQGL PNQLPVHPDL EQVPPSQQEQ GHSVHSSSMV MRTLNHPLGG
2101 EFSEAPLSTS VPSETTSDNL QITTQPSDGL EEKLDSDDPS VKELDVKDLE GVEVKDLDDE
2161 DLENLNLDTE DGKVVELDTL DNLETNDPNL DDLLRSGEFD IIAYTDPELD MGDKKSMFNE
2221 ELDLPIDDKL DNQCVSVEPK KKEQENKTLV LSDKHSPQKK STVTNEVKTE VLSPNSKVES
2281 KCETEKNDEN KDNVDTPCSQ ASAHSDLNDG EKTSLHPCDP DLFEKRTNRE TAGPSANVIQ
2341 ASTQLPAQDV INSCGITGST PVLSSLLANE KSDNSDIRPS GSPPPPTLPA SPSNHVSSLP
2401 PFIAPPGRVL DNAMNSNVTV VSRVNHVFSQ GVQVNPGLIP GQSTVNHSLG TGKPATQTGP
2461 QTSQSGTSSM SGPQQLMIPQ TLAQQNRERP LLLEEQPLLL QDLLDQERQE QQQQRQMQAM
2521 IRQRSEPFFP NIDFDAITDP IMKAKMVALK GINKVMAQNN LGMPPMVMSR FPFMGQVVTG
2581 TQNSEGQNLG PQAIPQDGSI THQISRPNPP NFGPGFVNDS QRKQYEEWLQ ETQQLLQMQQ
2641 KYLEEQIGAH RKSKKALSAK QRTAKKAGRE FPEEDAEQLK HVTEQQSMVQ KQLEQIRKQQ
2701 KEHAELIEDY RIKQQQQCAM APPTMMPSVQ PQPPLIPGAT PPTMSQPTFP MVPQQLQHQQ
2761 HTTVISGHTS PVRMPSLPGW QPNSAPAHLP LNPPRIQPPI AQLPIKTCTP APGTVSNANP
2821 QSGPPPRVEF DDNNPFSESF QERERKERLR EQQERQRIQL MQEVDRQRAL QQRMEMEQHG
2881 MVGSEISSSR TSVSQIPFYS SDLPCDFMQP LGPLQQSPQH QQQMGQVLQQ QNIQQGSINS
2941 PSTQTFMQTN ERRQVGPPSF VPDSPSIPVG SPNFSSVKQG HGNLSGTSFQ QSPVRPSFTP
3001 ALPAAPPVAN SSLPCGQDST ITHGHSYPGS TQSLIQLYSD IIPEEKGKKK RTRKKKRDDD
3061 AESTKAPSTP HSDITAPPTP GISETTSTPA VSTPSELPQQ ADQESVEPVG PSTPNMAAGQ
3121 LCTELENKLP NSDFSQATPN QQTYANSEVD KLSMETPAKT EEIKLEKAET ESCPGQEEPK
3181 LEEQNGSKVE GNAVACPVSS AQSPPHSAGA PAAKGDSGNE LLKHLLKNKK SSSLLNQKPE
3241 GSICSEDDCT KDNKLVEKQN PAEGLQTLGA QMQGGFGCGN QLPKTDGGSE TKKQRSKRTQ
3301 RTGEKAAPRS KKKK
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