LOCUS AAH92517.1 1511 aa PRT HUM 19-MAR-2009
DEFINITION Homo sapiens DNMT1 protein protein.
ACCESSION BC092517-1
PROTEIN_ID AAH92517.1
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5246)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 5246)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (04-APR-2005) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Louis M. Staudt, M.D., Ph.D.
cDNA Library Preparation: M. Bento Soares, University of Iowa
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 199 Row: c Column: 19
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4503350
The stop codon of the CDS annotated on this record is located > 55
bases upstream of a splice junction, and therefore the mRNA is
predicted to be subject to nonsense-mediated mRNA decay (NMD).
FEATURES Qualifiers
source /db_xref="H-InvDB:HIT000334491"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:104992 IMAGE:3077831"
/tissue_type="Lymph, normal germinal center B cells"
/clone_lib="NIH_MGC_50"
/lab_host="DH10B"
/note="Vector: pT7T3-Pac"
protein /gene="DNMT1"
/gene_synonym="AIM"
/gene_synonym="CXXC9"
/gene_synonym="MCMT"
/db_xref="GeneID:1786"
/db_xref="HGNC:HGNC:2976"
/db_xref="MIM:126375"
BEGIN
1 MADANSPPKP LSKPRTPRRS KSDGEAKRSR DPPASASQVT GIRAEPSPSP RITRKSTRQT
61 TITSHFAKGP AKRKPQEESE RAKSDESIKE EDKDQDEKRR RVTSRERVAR PLPAEEPERA
121 KSGTRTEKEE ERDEKEEKRL RSQTKEPTPK QKLKEEPDRE ARAGVQADED EDGDEKDEKK
181 HRSQPKDLAA KRRPEEKEPE KVNPQISDEK DEDEKEEKRR KTTPKEPTEK KMARAKTVMN
241 SKTHPPKCIQ CGQYLDDPDL KYGQHPPDAV DEPQMLTNEK LSIFDANESG FESYEALPQH
301 KLTCFSVYCK HGHLCPIDTG LIEKNIELFF SGSAKPIYDD DPSLEGGVNG KNLGPINEWW
361 ITGFDGGEKA LIGFSTSFAE YILMDPSPEY APIFGLMQEK IYISKIVVEF LQSNSDSTYE
421 DLINKIETTV PPSGLNLNRF TEDSLLRHAQ FVVEQVESYD EAGDSDEQPI FLTPCMRDLI
481 KLAGVTLGQR RAQARRQTIR HSTREKDRGP TKATTTKLVY QIFDTFFAEQ IEKDDREDKE
541 NAFKRRRCGV CEVCQQPECG KCKACKDMVK FGGSGRSKQA CQERRCPNMA MKEADDDEEV
601 DDNIPEMPSP KKMHQGKKKK QNKNRISWVG EAVKTDGKKS YYKKVCIDAE TLEVGDCVSV
661 IPDDSSKPLY LARVTALWED SSNGQMFHAH WFCAGTDTVL GATSDPLELF LVDECEDMQL
721 SYIHSKVKVI YKAPSENWAM EGGMDPESLL EGDDGKTYFY QLWYDQDYAR FESPPKTQPT
781 EDNKFKFCVS CARLAEMRQK EIPRVLEQLE DLDSRVLYYS ATKNGILYRV GDGVYLPPEA
841 FTFNIKLSSP VKRPRKEPVD EDLYPEHYRK YSDYIKGSNL DAPEPYRIGR IKEIFCPKKS
901 NGRPNETDIK IRVNKFYRPE NTHKSTPASY HADINLLYWS DEEAVVDFKA VQGRCTVEYG
961 EDLPECVQVY SMGGPNRFYF LEAYNAKSKS FEDPPNHARS PGNKGKGKGK GKGKPKSQAC
1021 EPSEPEIEIK LPKLRTLDVF SGCGGLSEGF HQAGISDTLW AIEMWDPAAQ AFRLNNPGST
1081 VFTEDCNILL KLVMAGETTN SRGQRLPQKG DVEMLCGGPP CQGFSGMNRF NSRTYSKFKN
1141 SLVVSFLSYC DYYRPRFFLL ENVRNFVSFK RSMVLKLTLR CLVRMGYQCT FGVLQAGQYG
1201 VAQTRRRAII LAAAPGEKLP LFPEPLHVFA PRACQLSVVV DDKKFVSNIT RLSSGPFRTI
1261 TVRDTMSDLP EVRNGASALE ISYNGEPQSW FQRQLRGAQY QPILRDHICK DMSALVAARM
1321 RHIPLAPGSD WRDLPNIEVR LSDGTMARKL RYTHHDRKNG RSSSGALRGV CSCVEAGKAC
1381 DPAARQFNTL IPWCLPHTGN RHNHWAGLYG RLEWDGFFST TVTNPEPMGK QGRVLHPEQH
1441 RVVSVRECAR SQGFPDTYRL FGNILDKHRQ VGNAVPPPLA KAIGLEIKLC MLAKARESAS
1501 AKIKEEEAAK D
//