LOCUS AAF65317.1 3674 aa PRT HUM 11-JUL-2000
DEFINITION Homo sapiens beta V spectrin protein.
ACCESSION AF233523-1
PROTEIN_ID AAF65317.1
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 11722)
AUTHORS Stabach,P.R. and Morrow,J.S.
TITLE Identification and characterization of beta V spectrin, a mammalian
ortholog of Drosophila beta H spectrin
JOURNAL J. Biol. Chem. 275 (28), 21385-21395 (2000)
PUBMED 10764729
REFERENCE 2 (bases 1 to 11722)
AUTHORS Stabach,P.R. and Morrow,J.S.
TITLE Direct Submission
JOURNAL Submitted (10-FEB-2000) Pathology, Yale Medical School, 310 Cedar
St., New Haven, CT 06510, USA
FEATURES Qualifiers
source /db_xref="H-InvDB:HIT000074689"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="15"
/tissue_type="retina; cerebellum; spinal chord"
protein /gene="BSPECV"
/note="beta spectrin; actin binding protein; cytoskeletal
protein; ortholog of Drosphila melanogaster beta heavy
spectrin; contains 30 spectrin repeat units"
BEGIN
1 MAGQPHSPRE LLGAAGHRSR RPSTELRVPP SPSLTMDSQY ETGHIRKLQA RHMQMQEKTF
61 TKWINNVFQC GQAGIKIRNL YTELADGIHL LRLLELISGE ALPPPSRGRL RVHFLENSSR
121 ALAFLRAKVP VPLIGPENIV DGDQTLILGL IWVIILRFQI SHISLDKEEF GASAALLSTK
181 EALLVWCQRK TASYTNVNIT DFSRSWSDGL GFNALIHAHR PDLLDYGSLR PDRPLHNLAF
241 AFLVAEQELG IAQLLDPEDV AAAQPDERSI MTYVSLYYHY CSRLHQGQTV QRRLTKILLQ
301 LQETELLQTQ YEQLVADLLR WIAEKQMQLE ARDFPDSLPA MRQLLAAFTI FRTQEKPPRL
361 QQRGAAEALL FRLQTALQAQ NRRPFLPHEG LGLAELSQCW AGLEWAEAAR SQALQQRLLQ
421 LQRLETLARR FQRKAALRES FLKDAEQVLD QARAPPASLA TVEAAVQRLG MLEAGILPQE
481 GRFQALAEIA DILRQEQYHS WADVARRQEE VTVRWQRLLQ HLQGQRKQVA DMQAVLSLLQ
541 EVEAASHQLE ELQEPARSTA CGQQLAEVVE LLQRHDLLEA QVSAHGAHVS HLAQQTAELD
601 SSLGTSVEVL QAKARTLAQL QQSLVALVRA RRALLEQTLQ RAEFLRNCEE EEAWLKECGQ
661 RVGNAALGRD LSQIAGALQK HKALEAEVHR HQAVCVDLVR RGRDLSARRP PTQPDPGERA
721 EAVQGGWQLL QTRVVGRGAR LQTALLVLQY FADAAEAASW LRERRSSLER ASCGQDQAAA
781 ETLLRRHVRL ERVLRAFAAE LRRLEEQGRA ASARASLFTV NSALSPPGES LRNPGPWSEA
841 SCHPGPGDAW KMALPAEPDP DFDPNTILQT QDHLSQDYES LRALAQLRRA RLEEAMALFG
901 FCSSCGELQL WLEKQTVLLQ RVQPQADTLE VMQLKYENFL TALAVGKGLW AEVSSSAEQL
961 RQRYPGNSTQ IQRQQEELSQ RWGQLEALKR EKAVQLAHSV EVCSFLQECG PTQVQLRDVL
1021 LQLEALQPGS SEDTRHALQL AQKKTLVLER RVYFLQSVVV KVEEPGYAES QPLQGQVETL
1081 QGLLKQVQEQ VAQRARRQAE TQARQSFLQE SQQLLLWAES VQAQLRSKEV SVDVASAQRL
1141 LREHQDLLEE IHLWQERLQQ LDAQSQPMAA LDCPDSQEVP NTLRVLGQQG QELKVLWEQR
1201 QQWLQEGLEL QKFGREVDGF TATCANHQAW LHLDNLGEDV REALSLLQQH REFGRLLSTL
1261 GPRAEALRAH GEKLVQSQHP AAHTVREQLQ SIQAQWTRLQ GRSEQRRRQL LASLQLQEWK
1321 QDVAELMQWM EEKGLMAAHE PSGARRNILQ TLKRHEAAES ELLATRRHVE ALQQVGRELL
1381 SRRPCGQEDI QTRLQGLRSK WEALNRKMTE RGDELQQAGQ QEQLLRQLQD AKEQLEQLEG
1441 ALQSSETGQD LRSSQRLQKR HQQLESESRT LAAKMAALAS MAHGMAASPA ILEETQKHLR
1501 RLELLQGHLA IRGLQLQASV ELHQFCHLSN MELSWVAEHM PHGSPTSYTE CLNGAQSLHR
1561 KHKELQVEVK AHQGQVQRVL SSGRSLAASG HPQAQHIVEQ CQELEGHWAE LERACEARAQ
1621 CLQQAVTFQQ YFLDVSELEG WVEEKRPLVS SRDYGRDEAA TLRLINKHQA LQEELAIYWS
1681 SMEELDQTAQ TLTGPEVPEQ QRVVQERLRE QLRALQELAA TRDRELEGTL RLHEFLREAE
1741 DLQGWLASQK QAAKGGESLG EDPEHALHLC TKFAKFQHQV EMGSQRVAAC RLLAESLLER
1801 GHSAGPMVRQ RQQDLQTAWS ELWELTQARG HALRDTETTL RVHRDLLEVL TQVQEKATSL
1861 PNNVARDLCG LEAQLRSHQG LERELVGTER QLQELLETAG RVQKLCPGPQ AHAVQQRQQA
1921 VTQAWAVLQR RMEQRRAQLE RARLLARFRT AVRDYASWAA RVRQDLQVEE SSQEPSSGPL
1981 KLSAHQWLRA ELEAREKLWQ QATQLGQQAL LAAGTPTKEV QEELRALQDQ RDQVYQTWAR
2041 KQERLQAEQQ EQLFLRECGR LEEILAAQEV SLKTSALGSS VEEVEQLIRK HEVFLKVLTA
2101 QDKKEAALRE RLKTLRRPRV RDRLPILLQR RMRVKELAES RGHALHASLL MASFTQAATQ
2161 AEDWIQAWAQ QLKEPVPPGD LRDKLKPLLK HQAFEAEVQA HEEVMTSVAK KGEALLAQSH
2221 PRAGEVSQRL QGLRKHWEDL RQAMALRGQE LEDRRNFLEF LQRVDLAEAW IQEKEVKMNV
2281 GDLGQDLEHC LQLRRRLREF RGNSAGDTVG DACIRSISDL SLQLKNRDPE EVKIICQRRS
2341 QLNNRWASFH GNLLRYQQQL EGALEIHVLS RELDNVTKRI QEKEALIQAL DCGKDLESVQ
2401 RLLRKHEELE REVHPIQAQV ESLEREVGRL CQRSPEAAHG LRHRQQEVAE SWWQLRSRAQ
2461 KRREALDALH QAQKLQAMLQ ELLVSAQRLR AQMDTSPAPR SPVEARRMLE EHQECKAELD
2521 SWTDSISLAR STGQQLLTAG HPFSSDIRQV LAGLEQELSS LEGAWQEHQL QLQQALELQL
2581 FLSSVEKMER WLCSKEDSLA SEGLWDPLAP MEPLLWKHKM LEWDLEVQAG KISALEATAR
2641 GLHQGGHPEA QSALGRCQAM LLRKEALFRQ AGTRRHRLEE LRQLQAFLQD SQEVAAWLRE
2701 KNLVALEEGL LDTAMLPAQL QKQQNFQAEL DASMHQQQEL QREGQRLLQG GHPASEAIQE
2761 RLEELGALWG ELQDNSQKKV AKLQKACEAL RLRRSMEELE NWLEPIEVEL RAPTVGQALP
2821 GVGELLGTQR ELEAAVDKKA RQAEALLGQA QAFVREGHCL AQDVEEQARR LLQRFKSLRE
2881 PLQERRTALE ARSLLLKFFR DADEEMAWVQ EKLPLAAAQD YGQSLSAVRH LQEQHQNLES
2941 EMSSHEALTR VVLGTGYKLV QAGHFAAHEV AARVQQLEKA MAHLRAEAAR RRLLLQQAQE
3001 AQQFLTELLE AGSWLAERGH VLDSEDMGHS AEATQALLRR LEATKRDLEA FSPRIERLQQ
3061 TAALLESRKN PESPKVLAQL QAVREAHAEL LRRAEARGHG LQEQLQLHQL ERETLLLDAW
3121 LTTKAATAES QDYGQDLEGV KVLEEKFDAF RKEVQSLGQA KVYALRKLAG TLERGAPRRY
3181 PHIQAQRSRI EAAWERLDQA IKARTENLAA AHEVHSFQQA AAELQGRMQE KTALMKGEDG
3241 GHSLSSVRTL QQQHRRLERE LEAMEKEVAR LQTEACRLGQ LHPAAPGGLA KVQEAWATLQ
3301 AKAQERGQWL AQAAQGHAFL GRCQELLAWA QERQELASSE ELAEDVAGAE QLLGQHEELG
3361 QEIRECRLQA QDLRQEGQQL VDNSHFMSAE VTECLQELEG RLQELEEAWA LRWQRCAESW
3421 GLQKLRQRLE QAEAWLACWE GLLLKPDYGH SVSDVELLLH RHQDLEKLLA AQEEKFAQMQ
3481 KTEMEQELLL QPQELKPGRA GSSLTSFQWR PSGHQGLGAQ LAETRDPQDA KGTPTMEGSL
3541 EFKQHLLPGG RQPSSSSWDS CRGTLQGSSL SLFLDERMAA EKVASIALLD LTGARCERLR
3601 GRHGRKHTFS LRLTSGAEIL FAAPSEEQAE SWWRALGSTA AQSLSPKLKA KPVSSLNECT
3661 TKDARPGCLL RSDP
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