LOCUS       AAD49675.1              1078 aa    PRT              VRL 15-OCT-2003
DEFINITION  Human betaherpesvirus 6B U90 protein.
ACCESSION   AF157706-91
PROTEIN_ID  AAD49675.1
SOURCE      Human betaherpesvirus 6B
  ORGANISM  Human betaherpesvirus 6B
            Viruses; Duplodnaviria; Heunggongvirae; Peploviricota;
            Herviviricetes; Herpesvirales; Orthoherpesviridae;
            Betaherpesvirinae; Roseolovirus; Roseolovirus humanbeta6b.
REFERENCE   1  (bases 19696 to 22886)
  AUTHORS   Pellett,P.E., Sanchez-Martinez,D., Dominguez,G., Black,J.B.,
            Anton,E., Greenamoyer,C. and Dambaugh,T.R.
  TITLE     A strongly immunoreactive virion protein of human herpesvirus 6
            variant B strain Z29: identification and characterization of the
            gene and mapping of a variant-specific monoclonal antibody reactive
            epitope
  JOURNAL   Virology 195 (2), 521-531 (1993)
   PUBMED   7687803
REFERENCE   2  (bases 64106 to 84963)
  AUTHORS   Stamey,F.R., Dominguez,G., Black,J.B., Dambaugh,T.R. and
            Pellett,P.E.
  TITLE     Intragenomic linear amplification of human herpesvirus 6B oriLyt
            suggests acquisition of oriLyt by transposition
  JOURNAL   J. Virol. 69 (1), 589-596 (1995)
   PUBMED   7983761
REFERENCE   3  (bases 64106 to 84963; 106012 to 126166)
  AUTHORS   Lindquester,G.J., Inoue,N., Allen,R.D., Castelli,J.W., Stamey,F.R.,
            Dambaugh,T.R., O'Brian,J.J., Danovich,R.M., Frenkel,N. and
            Pellett,P.E.
  TITLE     Restriction endonuclease mapping and molecular cloning of the human
            herpesvirus 6 variant B strain Z29 genome
  JOURNAL   Arch. Virol. 141 (2), 367-379 (1996)
   PUBMED   8634027
REFERENCE   4  (bases 64106 to 84963)
  AUTHORS   Lindquester,G.J., O'Brian,J.J., Anton,E.D., Greenamoyer,C.A.,
            Pellett,P.E. and Dambaugh,T.R.
  TITLE     Genetic content of a 20.9 kb segment of human herpesvirus 6B strain
            Z29 spanning the homologs of human herpesvirus 6A genes U40-57 and
            containing the origin of DNA replication
  JOURNAL   Arch. Virol. 142 (1), 103-123 (1997)
   PUBMED   9155876
REFERENCE   5  (bases 106012 to 126166)
  AUTHORS   Lindquester,G.J., Greenamoyer,C.A., Anton,E.D., O'Brian,J.J.,
            Pellett,P.E. and Dambaugh,T.R.
  TITLE     Comparison of a 20 kb region of human herpesvirus 6B with other
            human beta herpesviruses reveals conserved replication genes and
            adjacent divergent open reading frames
  JOURNAL   Arch. Virol. 142 (1), 193-204 (1997)
   PUBMED   9155884
REFERENCE   6  (bases 1 to 162114)
  AUTHORS   Dominguez,G., Dambaugh,T.R., Stamey,F.R., Dewhurst,S., Inoue,N. and
            Pellett,P.E.
  TITLE     Human herpesvirus 6B genome sequence: coding content and comparison
            with human herpesvirus 6A
  JOURNAL   J. Virol. 73 (10), 8040-8052 (1999)
   PUBMED   10482553
REFERENCE   7  (bases 19696 to 22886)
  AUTHORS   Pellett,P.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-1993) Herpesvirus Section, Centers for Disease
            Control and Prevention, 1600 Clifton Road, Mailstop G18, Atlanta,
            GA 30333, USA
REFERENCE   8  (bases 64106 to 84963; 106012 to 126166)
  AUTHORS   Pellett,P.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-OCT-1993) Herpesvirus Section, Centers for Disease
            Control and Prevention, 1600 Clifton Road, Mailstop G18, Atlanta,
            GA 30333, USA
REFERENCE   9  (bases 1 to 162114)
  AUTHORS   Pellett,P.E., Dominguez,G., Dambaugh,T.R., Stamey,F.R., Dewhurst,S.
            and Inoue,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JUN-1999) Herpesvirus Section, Centers for Disease
            Control and Prevention, 1600 Clifton Road, Mailstop G18, Atlanta,
            GA 30333, USA
  REMARK    Sequence updated by submitter
COMMENT     On or before Aug 16, 1999 this sequence version replaced L14772.1,
            L16947.1, L13162.1.
FEATURES             Qualifiers
     source          /organism="Human betaherpesvirus 6B"
                     /mol_type="genomic DNA"
                     /strain="Z29"
                     /db_xref="taxon:32604"
                     /note="variant B"
     protein         /gene="U90"
                     /note="IE-1; IE-A, transactivator"
     intron_pos      32:2 (1/2)
     intron_pos      103:1 (2/2)
BEGIN
        1 MESAKDTTST SMFILGKPSG NNMESNEERM QNYHPDPVVE ESIKEILEES LKCDVSFESL
       61 LFPELEAFDL FIPESSNDIA SKNVSYSSNV EEGASDEFKT LVAQSVGNCI QSIGASVKAA
      121 MKQEQSNMED NLINSAGLLT LHRSMLERLV LEQLGQLINI NLLSSASSQF VSCYAKMLSG
      181 KNLDFFNWCE PRFIVFACDK FDGLVKKIAS ESRDLLMDLK ANMNNQFITA LKNIFSKAYV
      241 ALDSGKLNMV ATSLLLMAHN KEMSNPEISN KEFCKQVNLL KQELLESRNE IIENHVKNMK
      301 MFQEFANKQM NQIFMDNCDK TFLKIHINCK NLITAAKNIG IAVLQSIVLC SNEFSWQYLK
      361 PRRHQFKITM MNMITHACEC IETIYDDTGL IKPLTSSDIM EGYIAINKNR ESSICDLNID
      421 PSESILLELA DFDEHGKYSE ESSIESIHED DDNVDYLKYM EVQSPTDNNI PTPSKNNESP
      481 TRQKLTNIHE KDVGKMYPDT PSPDVPGKSK EAKTFIEYSR QIGKEQTSPN CVCTASVTDL
      541 GGPDNFKSIT GLESGKHFLI KKLLETQPDS VVVETGSGQQ DILAYSPDKR SQTKEWIQEK
      601 GSNSKCTETL PGMTFTNSAT PVKSHGAIQD TLNPESKLDK EMEAVESLVN LCDGFHDNPL
      661 ISEMITFGYE TDHSAPYESE SDNNDETDYI ADCDSTVRTN NIHMNNTNEN TPFSKSLYSP
      721 PEVTPSKEDH KTEKIVAVSQ KCKSKKRTAK RKNVPIKPSK SKKIKLDRLP ETTNVIVISS
      781 ESEDEEDGNN IIDKSMLEKT IKSEPNSESS SESDDCTSED NYLHLSDYDK VINNGHCQSK
      841 GFPSPVFTIP IRSMPGTHDI RNKFVPKKHW LWFMRKTHKV DNCVIHSSAK MNVKNDSDVT
      901 EANHCFINHF VPIKTDDEEY EKENVSYTYS KIQDSKTDLE DITPTKKLIT EMVMENFMDL
      961 TDIIKHGIAK HCQDLSSKYT VITHTACEKN LNVANSQNLV TAETQIFDPQ GTGNNSPILN
     1021 IINDTTCQND ENRCTEGTSN DNEKCTIRSD CNSDKMEVFK LDGYPSDYDP FEENAQIY
//