LOCUS       AAD49642.1               804 aa    PRT              VRL 15-OCT-2003
DEFINITION  Human betaherpesvirus 6B U28 protein.
ACCESSION   AF157706-34
PROTEIN_ID  AAD49642.1
SOURCE      Human betaherpesvirus 6B
  ORGANISM  Human betaherpesvirus 6B
            Viruses; Duplodnaviria; Heunggongvirae; Peploviricota;
            Herviviricetes; Herpesvirales; Orthoherpesviridae;
            Betaherpesvirinae; Roseolovirus; Roseolovirus humanbeta6b.
REFERENCE   1  (bases 19696 to 22886)
  AUTHORS   Pellett,P.E., Sanchez-Martinez,D., Dominguez,G., Black,J.B.,
            Anton,E., Greenamoyer,C. and Dambaugh,T.R.
  TITLE     A strongly immunoreactive virion protein of human herpesvirus 6
            variant B strain Z29: identification and characterization of the
            gene and mapping of a variant-specific monoclonal antibody reactive
            epitope
  JOURNAL   Virology 195 (2), 521-531 (1993)
   PUBMED   7687803
REFERENCE   2  (bases 64106 to 84963)
  AUTHORS   Stamey,F.R., Dominguez,G., Black,J.B., Dambaugh,T.R. and
            Pellett,P.E.
  TITLE     Intragenomic linear amplification of human herpesvirus 6B oriLyt
            suggests acquisition of oriLyt by transposition
  JOURNAL   J. Virol. 69 (1), 589-596 (1995)
   PUBMED   7983761
REFERENCE   3  (bases 64106 to 84963; 106012 to 126166)
  AUTHORS   Lindquester,G.J., Inoue,N., Allen,R.D., Castelli,J.W., Stamey,F.R.,
            Dambaugh,T.R., O'Brian,J.J., Danovich,R.M., Frenkel,N. and
            Pellett,P.E.
  TITLE     Restriction endonuclease mapping and molecular cloning of the human
            herpesvirus 6 variant B strain Z29 genome
  JOURNAL   Arch. Virol. 141 (2), 367-379 (1996)
   PUBMED   8634027
REFERENCE   4  (bases 64106 to 84963)
  AUTHORS   Lindquester,G.J., O'Brian,J.J., Anton,E.D., Greenamoyer,C.A.,
            Pellett,P.E. and Dambaugh,T.R.
  TITLE     Genetic content of a 20.9 kb segment of human herpesvirus 6B strain
            Z29 spanning the homologs of human herpesvirus 6A genes U40-57 and
            containing the origin of DNA replication
  JOURNAL   Arch. Virol. 142 (1), 103-123 (1997)
   PUBMED   9155876
REFERENCE   5  (bases 106012 to 126166)
  AUTHORS   Lindquester,G.J., Greenamoyer,C.A., Anton,E.D., O'Brian,J.J.,
            Pellett,P.E. and Dambaugh,T.R.
  TITLE     Comparison of a 20 kb region of human herpesvirus 6B with other
            human beta herpesviruses reveals conserved replication genes and
            adjacent divergent open reading frames
  JOURNAL   Arch. Virol. 142 (1), 193-204 (1997)
   PUBMED   9155884
REFERENCE   6  (bases 1 to 162114)
  AUTHORS   Dominguez,G., Dambaugh,T.R., Stamey,F.R., Dewhurst,S., Inoue,N. and
            Pellett,P.E.
  TITLE     Human herpesvirus 6B genome sequence: coding content and comparison
            with human herpesvirus 6A
  JOURNAL   J. Virol. 73 (10), 8040-8052 (1999)
   PUBMED   10482553
REFERENCE   7  (bases 19696 to 22886)
  AUTHORS   Pellett,P.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-1993) Herpesvirus Section, Centers for Disease
            Control and Prevention, 1600 Clifton Road, Mailstop G18, Atlanta,
            GA 30333, USA
REFERENCE   8  (bases 64106 to 84963; 106012 to 126166)
  AUTHORS   Pellett,P.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-OCT-1993) Herpesvirus Section, Centers for Disease
            Control and Prevention, 1600 Clifton Road, Mailstop G18, Atlanta,
            GA 30333, USA
REFERENCE   9  (bases 1 to 162114)
  AUTHORS   Pellett,P.E., Dominguez,G., Dambaugh,T.R., Stamey,F.R., Dewhurst,S.
            and Inoue,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JUN-1999) Herpesvirus Section, Centers for Disease
            Control and Prevention, 1600 Clifton Road, Mailstop G18, Atlanta,
            GA 30333, USA
  REMARK    Sequence updated by submitter
COMMENT     On or before Aug 16, 1999 this sequence version replaced L14772.1,
            L16947.1, L13162.1.
FEATURES             Qualifiers
     source          /organism="Human betaherpesvirus 6B"
                     /mol_type="genomic DNA"
                     /strain="Z29"
                     /db_xref="taxon:32604"
                     /note="variant B"
     protein         /gene="U28"
                     /note="large ribonuclease reductase"
BEGIN
        1 MKRKERRINK DFGYNRKCVC HYEASQKRFC YSQYSCASVL YERVRDIAKI MDRLDSGLDA
       61 WCLRDAIISV LRATHCVPRV DRMLGRWYLK TSIFYDFCPD DLILSCPNVI MPNVLNFVKK
      121 YRDFIRSVLY KVSVSWKNQY MPGVLGASRF LEEISNSLNG VEESIPCIYL RMCATLTEIV
      181 LRNGYLREIY QENPYVIFEE LAFSLFTQKW VLPFSCMTNL GLVEKANSTV FDVAIYNTCL
      241 YSLADFITVN GEHLFPALLN GSNISMNVTR YQQEAKNIFE ILLSQIQVVE RDTDKTVQLT
      301 VYVEVWHVSA LTWLDLYQVL PETSRVTFCL IIPGIFMDRY ELKRAQWSLF HKNIAFELGK
      361 CDEVTFSTKY LEFERTTDHA KITMASFVEK ICRCLKRGRM GLIFRKNVYQ YSMIPHVPLY
      421 CGGDFLDVLP VRDGINTCLR MLLNVVHFLG DEVSDELTEE IDFVRLQCKF FMFNELRRVV
      481 RKMVLVANAV IDYAVDNKDF LREGIVDGRS LGICITGLHS VFMTVGLSYA HPDACRLYRM
      541 MCEHIYYTCV RTSVDCCMKG AEPCNLFDRS KYALGMLYFD QFDNVECTLP EELWTTLRKD
      601 VLMHGVRNIH FTAGTAMQKE FDIINSSESF WPMEDNKILR RSNIKVVIGK DGLNDVTSVY
      661 SSELKSLYIP VYNNLLLNRF NKHQQYLKTV GYRVLNVDTN LFTDKELDDL AVFKDGFSYP
      721 LNDLIEMYKS GLPFLDQGQA NVFYFNDTVS LKHLLPLLYK TGFKVAMYKV LCSSEMYKHL
      781 DLSNPLPLIG KCSDGVVMHV KNIL
//