LOCUS AAD40475.1 226 aa PRT HUM 23-JUN-1999 DEFINITION Homo sapiens DM domain-containing transcription factor DMRT2 protein. ACCESSION AF130729-1 PROTEIN_ID AAD40475.1 SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 1010) AUTHORS Raymond,C.S., Parker,E.D., Kettlewell,J.R., Brown,L.G., Page,D.C., Kusz,K., Jaruzelska,J., Reinberg,Y., Flejter,W.L., Bardwell,V.J., Hirsch,B. and Zarkower,D. TITLE A region of human chromosome 9p required for testis development contains two genes related to known sexual regulators JOURNAL Hum. Mol. Genet. 8 (6), 989-996 (1999) PUBMED 10332030 REFERENCE 2 (bases 1 to 1010) AUTHORS Raymond,C.S., Parker,E.D., Kettlewell,J.R., Bardwell,V.J. and Zarkower,D. TITLE Direct Submission JOURNAL Submitted (24-FEB-1999) Genetics, Cell Biology and Development, University of Minnesota, Box 206, 420 Delaware St. SE, Minneapolis, MN 55455, USA FEATURES Qualifiers source /db_xref="H-InvDB:HIT000070725" /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /chromosome="9" /map="9p24.3" /tissue_type="testis" /dev_stage="adult" /note="maps to region required for testis development" protein /gene="DMRT2" /note="contains DNA-binding domain (DM) that chelates zinc and has conserved cysteine and histidine residues; similar to DOUBLESEX and MAB-3 proteins; distinct from other classes of zinc fingers" BEGIN 1 MADPQAGSAA GDWEIDVESL ELEEDVCGAP RSTPPGPSPP PADGDCEDDE DDDGVDEDAE 61 EEGDGEEAGA SPGMPGQPEQ RGGPQPRPPL APQASPAGTG PRERCTPAGG GAEPRKLSRT 121 PKCARCRNHG VVSCLKGHKR FCRWRDCQCA NCLLVVERQR VMAAQVALRR QQATEDKKGL 181 SGKQNNFERK AVYQRQVRAP SLLAKSILEV LLGLFYSYYV YIMNHL //