LOCUS       AAB48112.1              1143 aa    PRT              VRL 26-JUL-2016
DEFINITION  Human spumaretrovirus pro-pol protein protein.
ACCESSION   U21247-2
PROTEIN_ID  AAB48112.1
SOURCE      Human spumaretrovirus
  ORGANISM  Human spumaretrovirus
            Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
            Ortervirales; Retroviridae; Spumaretrovirinae; Spumavirus; Simian
            foamy virus.
REFERENCE   1  (bases 9435 to 10337)
  AUTHORS   Flugel,R.M., Rethwilm,A., Maurer,B. and Darai,G.
  TITLE     Nucleotide sequence analysis of the env gene and its flanking
            regions of the human spumaretrovirus reveals two novel genes
  JOURNAL   EMBO J. 6 (7), 2077-2084 (1987)
   PUBMED   2820721
  REMARK    Erratum:[EMBO J 1990 Nov;9(11):3806]
REFERENCE   2  (bases 5337 to 11954)
  AUTHORS   Maurer,B., Bannert,H., Rethwilm,A., Darai,G. and Fluegel,R.M.
  TITLE     Characterization of the ENV gene and of two novel coding regions of
            the human spumaretrovirus
  JOURNAL   (in) Bolognesi,D.P. (Ed.);
            HUMAN RETROVIRUSES, CANCER AND AIDS: 75-88;
            Alan Liss, Inc., New York (1988)
REFERENCE   3  (bases 1 to 5342)
  AUTHORS   Maurer,B., Bannert,H., Darai,G. and Flugel,R.M.
  TITLE     Analysis of the primary structure of the long terminal repeat and
            the gag and pol genes of the human spumaretrovirus
  JOURNAL   J. Virol. 62 (5), 1590-1597 (1988)
   PUBMED   2451755
REFERENCE   4  (bases 1 to 11954)
  AUTHORS   Muranyi,W. and Flugel,R.M.
  TITLE     Analysis of splicing patterns of human spumaretrovirus by
            polymerase chain reaction reveals complex RNA structures
  JOURNAL   J. Virol. 65 (2), 727-735 (1991)
   PUBMED   1846194
REFERENCE   5  (bases 1 to 11954)
  AUTHORS   Lochelt,M., Zentgraf,H. and Flugel,R.M.
  TITLE     Construction of an infectious DNA clone of the full-length human
            spumaretrovirus genome and mutagenesis of the bel 1 gene
  JOURNAL   Virology 184 (1), 43-54 (1991)
   PUBMED   1651600
REFERENCE   6  (bases 1 to 11954)
  AUTHORS   Lochelt,M., Muranyi,W. and Flugel,R.M.
  TITLE     Human foamy virus genome possesses an internal, Bel-1-dependent and
            functional promoter
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 90 (15), 7317-7321 (1993)
   PUBMED   8394017
REFERENCE   7  (bases 1 to 11954)
  AUTHORS   Weissenberger,J. and Flugel,R.M.
  TITLE     Identification and characterization of the Bel 3 protein of human
            foamy virus
  JOURNAL   AIDS Res. Hum. Retroviruses 10 (5), 595-600 (1994)
   PUBMED   7917520
REFERENCE   8  (bases 1 to 11954)
  AUTHORS   Kogel,D., Aboud,M. and Flugel,R.M.
  TITLE     Mutational analysis of the reverse transcriptase and ribonuclease H
            domains of the human foamy virus
  JOURNAL   Nucleic Acids Res. 23 (14), 2621-2625 (1995)
   PUBMED   7544460
REFERENCE   9  (bases 1 to 11954)
  AUTHORS   Lochelt,M. and Flugel,R.M.
  TITLE     The human foamy virus pol gene is expressed as a Pro-Pol
            polyprotein and not as a Gag-Pol fusion protein
  JOURNAL   J. Virol. 70 (2), 1033-1040 (1996)
   PUBMED   8551561
REFERENCE   10  (bases 1 to 11954)
  AUTHORS   Bodem,J., Lochelt,M., Winkler,I., Flower,R.P., Delius,H. and
            Flugel,R.M.
  TITLE     Characterization of the spliced pol transcript of feline foamy
            virus: the splice acceptor site of the pol transcript is located in
            gag of foamy viruses
  JOURNAL   J. Virol. 70 (12), 9024-9027 (1996)
   PUBMED   8971036
  REMARK    Erratum:[J Virol 1997 Nov;71(11):8952]
REFERENCE   11  (bases 1 to 11954)
  AUTHORS   Fluegel,R.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-FEB-1995) Rolf M. Fluegel, Abtlg. Retroviral Gene
            Expression, DKFZ-ATZ, Heidelberg 69009, Germany
FEATURES             Qualifiers
     source          /organism="Human spumaretrovirus"
                     /mol_type="genomic RNA"
                     /db_xref="taxon:11963"
                     /clone="pHSRV13, infectious"
     protein         /citation=[10]
BEGIN
        1 MNPLQLLQPL PAEIKGTKLL AHWDSGATIT CIPESFLEDE QPIKKTLIKT IHGEKQQNVY
       61 YVTFKVKGRK VEAEVIASPY EYILLSPTDV PWLTQQPLQL TILVPLQEYQ EKILSKTALP
      121 EDQKQQLKTL FVKYDNLWQH WENQVGHRKI RPHNIATGDY PPRPQKQYPI NPKAKPSIQI
      181 VIDDLLKQGV LTPQNSTMNT PVYPVPKPDG RWRMVLDYRE VNKTIPLTAA QNQHSAGILA
      241 TIVRQKYKTT LDLANGFWAH PITPESYWLT AFTWQGKQYC WTRLPQGFLN SPALFTADVV
      301 DLLKEIPNVQ VYVDDIYLSH DDPKEHVQQL EKVFQILLQA GYVVSLKKSE IGQKTVEFLG
      361 FNITKEGRGL TDTFKTKLLN ITPPKDLKQL QSILGLLNFA RNFIPNFAEL VQPLYNLIAS
      421 AKGKYIEWSE ENTKQLNMVI EALNTASNLE ERLPEQRLVI KVNTSPSAGY VRYYNETGKK
      481 PIMYLNYVFS KAELKFSMLE KLLTTMHKAL IKAMDLAMGQ EILVYSPIVS MTKIQKTPLP
      541 ERKALPIRWI TWMTYLEDPR IQFHYDKTLP ELKHIPDVYT SSQSPVKHPS QYEGVFYTDG
      601 SAIKSPDPTK SNNAGMGIVH ATYKPEYQVL NQWSIPLGNH TAQMAEIAAV EFACKKALKI
      661 PGPVLVITDS FYVAESANKE LPYWKSNGFV NNKKKPLKHI SKWKSIAECL SMKPDITIQH
      721 EKGISLQIPV FILKGNALAD KLATQGSYVV NCNTKKPNLD AELDQLLQGH YIKGYPKQYT
      781 YFLEDGKVKV SRPEGVKIIP PQSDRQKIVL QAHNLAHTGR EATLLKIANL YWWPNMRKDV
      841 VKQLGRCQQC LITNASNKAS GPILRPDRPQ KPFDKFFIDY IGPLPPSQGY LYVLVVVDGM
      901 TGFTWLYPTK APSTSATVKS LNVLTSIAIP KVIHSDQGAA FTSSTFAEWA KERGIHLEFS
      961 TPYHPQSGSK VERKNSDIKR LLTKLLVGRP TKWYDLLPVV QLALNNTYSP VLKYTPHQLL
     1021 FGIDSNTPFA NQDTLDLTRE EELSLLQEIR TSLYHPSTPP ASSRSWSPVV GQLVQERVAR
     1081 PASLRPRWHK PSTVLKVLNP RTVVILDHLG NNRTVSIDNL KPTSHQNGTT NDTATMDHLE
     1141 KNE
//