LOCUS       AAB06357.1               662 aa    PRT              VRL 15-OCT-2003
DEFINITION  Human betaherpesvirus 6B U74 protein.
ACCESSION   AF157706-78
PROTEIN_ID  AAB06357.1
SOURCE      Human betaherpesvirus 6B
  ORGANISM  Human betaherpesvirus 6B
            Viruses; Duplodnaviria; Heunggongvirae; Peploviricota;
            Herviviricetes; Herpesvirales; Orthoherpesviridae;
            Betaherpesvirinae; Roseolovirus; Roseolovirus humanbeta6b.
REFERENCE   1  (bases 19696 to 22886)
  AUTHORS   Pellett,P.E., Sanchez-Martinez,D., Dominguez,G., Black,J.B.,
            Anton,E., Greenamoyer,C. and Dambaugh,T.R.
  TITLE     A strongly immunoreactive virion protein of human herpesvirus 6
            variant B strain Z29: identification and characterization of the
            gene and mapping of a variant-specific monoclonal antibody reactive
            epitope
  JOURNAL   Virology 195 (2), 521-531 (1993)
   PUBMED   7687803
REFERENCE   2  (bases 64106 to 84963)
  AUTHORS   Stamey,F.R., Dominguez,G., Black,J.B., Dambaugh,T.R. and
            Pellett,P.E.
  TITLE     Intragenomic linear amplification of human herpesvirus 6B oriLyt
            suggests acquisition of oriLyt by transposition
  JOURNAL   J. Virol. 69 (1), 589-596 (1995)
   PUBMED   7983761
REFERENCE   3  (bases 64106 to 84963; 106012 to 126166)
  AUTHORS   Lindquester,G.J., Inoue,N., Allen,R.D., Castelli,J.W., Stamey,F.R.,
            Dambaugh,T.R., O'Brian,J.J., Danovich,R.M., Frenkel,N. and
            Pellett,P.E.
  TITLE     Restriction endonuclease mapping and molecular cloning of the human
            herpesvirus 6 variant B strain Z29 genome
  JOURNAL   Arch. Virol. 141 (2), 367-379 (1996)
   PUBMED   8634027
REFERENCE   4  (bases 64106 to 84963)
  AUTHORS   Lindquester,G.J., O'Brian,J.J., Anton,E.D., Greenamoyer,C.A.,
            Pellett,P.E. and Dambaugh,T.R.
  TITLE     Genetic content of a 20.9 kb segment of human herpesvirus 6B strain
            Z29 spanning the homologs of human herpesvirus 6A genes U40-57 and
            containing the origin of DNA replication
  JOURNAL   Arch. Virol. 142 (1), 103-123 (1997)
   PUBMED   9155876
REFERENCE   5  (bases 106012 to 126166)
  AUTHORS   Lindquester,G.J., Greenamoyer,C.A., Anton,E.D., O'Brian,J.J.,
            Pellett,P.E. and Dambaugh,T.R.
  TITLE     Comparison of a 20 kb region of human herpesvirus 6B with other
            human beta herpesviruses reveals conserved replication genes and
            adjacent divergent open reading frames
  JOURNAL   Arch. Virol. 142 (1), 193-204 (1997)
   PUBMED   9155884
REFERENCE   6  (bases 1 to 162114)
  AUTHORS   Dominguez,G., Dambaugh,T.R., Stamey,F.R., Dewhurst,S., Inoue,N. and
            Pellett,P.E.
  TITLE     Human herpesvirus 6B genome sequence: coding content and comparison
            with human herpesvirus 6A
  JOURNAL   J. Virol. 73 (10), 8040-8052 (1999)
   PUBMED   10482553
REFERENCE   7  (bases 19696 to 22886)
  AUTHORS   Pellett,P.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JUL-1993) Herpesvirus Section, Centers for Disease
            Control and Prevention, 1600 Clifton Road, Mailstop G18, Atlanta,
            GA 30333, USA
REFERENCE   8  (bases 64106 to 84963; 106012 to 126166)
  AUTHORS   Pellett,P.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-OCT-1993) Herpesvirus Section, Centers for Disease
            Control and Prevention, 1600 Clifton Road, Mailstop G18, Atlanta,
            GA 30333, USA
REFERENCE   9  (bases 1 to 162114)
  AUTHORS   Pellett,P.E., Dominguez,G., Dambaugh,T.R., Stamey,F.R., Dewhurst,S.
            and Inoue,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JUN-1999) Herpesvirus Section, Centers for Disease
            Control and Prevention, 1600 Clifton Road, Mailstop G18, Atlanta,
            GA 30333, USA
  REMARK    Sequence updated by submitter
COMMENT     On or before Aug 16, 1999 this sequence version replaced L14772.1,
            L16947.1, L13162.1.
FEATURES             Qualifiers
     source          /organism="Human betaherpesvirus 6B"
                     /mol_type="genomic DNA"
                     /strain="Z29"
                     /db_xref="taxon:32604"
                     /note="variant B"
     protein         /gene="U74"
                     /note="helicase/primase complex"
BEGIN
        1 MHLRGCACHL SLYCVYNDWE NKIYRVPIFQ CLFLEAETRS LKTFLIRGQS LDQESLNEIE
       61 VTRKETMLWD LQEQSNMMDK KIAAISSLIM NNGELLRKLS KFFVPLTVVL GDDGLEILEA
      121 YVCGEEPMLP LDTVPVILRC VGDYAALDTK HLLSNECTQA SKKLRFGYSV MDFHFSLTVS
      181 DVKICFSHTD TGEAVCEKMK QIFYFSVCAF GGEQVLLVTP KNAYALLFDD DLCLLLLQSV
      241 FAFLHEKIFA VYKQVLVQLC EYIGPDLWPF GNERSVSFIG YPNLWLLSVS DLERRVPDTT
      301 YICREILSFC GLAPILGPRG RHAIPVIREL SVEMPGSETS LQRFRFNSQY VSSESLCFQT
      361 GPEDTHLFFS DSDMYVVTLP DCLRLLLKST VPRAFLPCFD ENATEIELLL KFMSRLQHRS
      421 YALFDAVIFM LDAFVSAFQR ACTLMEMRWL LVRDLHVFYL TCDGKDSHVV MPLLQTAVEN
      481 CWEKITEIKQ RPAFQCMEIS RCGFVFYARF FLSSGLSQSK EAHWTVTASK YLSACIRANK
      541 TGLCFASITV YFQDMMCVFI ANRYNVSYWI EEFDPNDYCL EYHEGLLDCS RYTAVMSEDG
      601 QLVRQARGIA LTDKINFSYY ILVTLRVLRR WVESKFEDVE QAEFIRWENR MLYEHIHLLH
      661 LN
//