LOCUS AAA37523.1 187 aa PRT ROD 24-SEP-2001 DEFINITION Mus musculus dihydrofolate reductase protein. ACCESSION L26316-1 PROTEIN_ID AAA37523.1 SOURCE Mus musculus (house mouse) ORGANISM Mus musculus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus. REFERENCE 1 (bases 91 to 217; 228 to 240; 318 to 343; 346 to 517) AUTHORS Nunberg,J.H., Kaufman,R.J., Chang,A.C., Cohen,S.N. and Schimke,R.T. TITLE Structure and genomic organization of the mouse dihydrofolate reductase gene JOURNAL Cell 19 (2), 355-364 (1980) PUBMED 6244105 REFERENCE 2 (bases 28 to 986) AUTHORS Setzer,D.R., McGrogan,M. and Schimke,R.T. TITLE Nucleotide sequence surrounding multiple polyadenylation sites in the mouse dihydrofolate reductase gene JOURNAL J. Biol. Chem. 257 (9), 5143-5147 (1982) PUBMED 6121807 REFERENCE 3 (bases 1 to 670) AUTHORS Crouse,G.F., Simonsen,C.C., McEwan,R.N. and Schimke,R.T. TITLE Structure of amplified normal and variant dihydrofolate reductase genes in mouse sarcoma S180 cells JOURNAL J. Biol. Chem. 257 (13), 7887-7897 (1982) PUBMED 6282858 REFERENCE 4 (bases 71 to 528) AUTHORS Simonsen,C.C. and Levinson,A.D. TITLE Isolation and expression of an altered mouse dihydrofolate reductase cDNA JOURNAL Proc. Natl. Acad. Sci. U.S.A. 80 (9), 2495-2499 (1983) PUBMED 6573667 REFERENCE 5 (bases 1 to 1499) AUTHORS Schilling,L.J. and Farnham,P.J. TITLE Transcriptional regulation of the dihydrofolate reductase/rep-3 locus JOURNAL Crit. Rev. Eukaryot. Gene Expr. 4 (1), 19-53 (1994) PUBMED 7987046 FEATURES Qualifiers source /organism="Mus musculus" /mol_type="mRNA" /db_xref="taxon:10090" /cell_line="sarcoma cell line s180" protein /gene="dhfr" BEGIN 1 MVRPLNCIVA VSQNMGIGKN GDLPWPPLRN EFKYFQRMTT TSSVEGKQNL VIMGRKTWFS 61 IPEKNRPLKD RINIVLSREL KEPPRGAHFL AKSLDDALRL IEQPELASKV DMVWIVGGSS 121 VYQEAMNQPG HLRLFVTRIM QEFESDTFFP EIDLGKYKLL PEYPGVLSEV QEEKGIKYKF 181 EVYEKKD //