LOCUS VTW47527.1 514 aa PRT CON 06-FEB-2024 DEFINITION Caenorhabditis elegans Ligand-Gated ion Channel protein. ACCESSION BX284606-1380 PROTEIN_ID VTW47527.1 SOURCE Caenorhabditis elegans ORGANISM Caenorhabditis elegans Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis. REFERENCE 1 (bases 1 to 17718942) AUTHORS WormBase. CONSRTM WormBase Consortium JOURNAL Submitted (04-FEB-2024) to the INSDC. WormBase Group, European Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email: help@wormbase.org REFERENCE 2 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. JOURNAL Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project: Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome Institute at Washington University, St. Louis, MO 63110, USA. REFERENCE 3 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. CONSRTM Caenorhabditis elegans Sequencing Consortium TITLE Genome sequence of the nematode C. elegans: a platform for investigating biology JOURNAL Science 282(5396), 2012-2018(1998). COMMENT Annotated features correspond to WormBase release WS292. Protein-coding gene structures below are the result of integration and manual review of the following types of data: ab initio predictions by Genefinder (P. Green and L. Hillier, pers. comm.); alignments to published proteins and cDNAs; genome sequence conservation with other nematodes (e.g. to C. briggsae using WABA: Genome Res. 2000. 10:1115-1125); sequence features (such as trans-splice and polyA sites). Sources of data: large-scale EST projects of Yuji Kohara (http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome cloning project (http://worfdb.dfci.harvard.edu); RST large-scale sequencing project (Genome Res. 2009. 19:2334-2342); IST library (Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010 Unpublished); UTRome EST data submission (UTRome v1 Mangone M. Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep sequencing data (454 read clusters - Makedonka Mitreva, unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66); Numerous data sets from the modENCODE project (Science. 2010. 330:1775-87); Individual C. elegans Nucleotide Database submissions; Personal communications with C. elegans researchers; Non-Coding gene structures below are derived using the following methods and data: ab initio prediction of tRNAs by tRNAscan-SE (Nucl. Acids. Res., 25, 955-964); integration and appraisal of miRNAs from miRBase (http://www.mirbase.org); integration and appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell. 2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87); manual curation of novel published ncRNAs from the literature. FEATURES Qualifiers source /organism="Caenorhabditis elegans" /chromosome="X" /strain="Bristol N2" /mol_type="genomic DNA" /db_xref="taxon:6239" protein /transl_table=1 /gene="lgc-58" /locus_tag="CELE_C45B2.4" /standard_name="C45B2.4l" /note="Partially confirmed by transcript evidence" /note="Product from WormBase gene class lgc" /db_xref="GOA:A0A4V0IK64" /db_xref="UniProtKB/TrEMBL:A0A4V0IK64" /db_xref="WormBase:WBGene00001587" intron_pos 13:2 (1/12) intron_pos 53:1 (2/12) intron_pos 129:0 (3/12) intron_pos 177:1 (4/12) intron_pos 222:1 (5/12) intron_pos 256:2 (6/12) intron_pos 309:2 (7/12) intron_pos 328:1 (8/12) intron_pos 372:0 (9/12) intron_pos 434:1 (10/12) intron_pos 468:2 (11/12) intron_pos 475:2 (12/12) BEGIN 1 MLLVSSIFLL LYRNSPKVEA SRSEPVPIYL DNLLNAGRQV YDNQSPPVQH DKEEVTVVEL 61 AMYIEGMSSF RTQTMDFQLD VYFQQFWRDP RLAHNETRRV LVKDKAVLHK MWKPDVYFAN 121 ARIAEFHEVT QPNFLVWIQP DGSILYDTRI SMVVVCTLNL EKWPLDSQRC HLRILSYAYT 181 TEQLVIKWKE DEPITRNPNI AMSDMHIVDL YPGLCDGNYS TGTWSCVTAE FFVKREITHH 241 VMQSYVPTTL IVVISWFSFW LDVEAVPARV SLAITTLLTL STQANAARMA LPEVSYMKAI 301 DVWMGACMMF VFGVMIEFTI VNYAQRQVMA SSLESVKSGN AEKKPSRGDL GAHARHLFLR 361 LRTNERQHLV EAAPVVQPPQ NEDAEAQEEV WAEQKETNLS EVWKESDPAE RLAHWNEKEN 421 DASSPLMGNG RAHVRYGAAE KMKNRKCNDS SRKKEKWSSA IKQIQKHKRN GSVFGKIAGR 481 NRAKKIDQTS RWIFPLTFII FNLTYWIYYL YWKE //