LOCUS SIU02481.1 404 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 FIG01386146: Possible exported protein, Rv1184c protein. ACCESSION LT708304-3895 PROTEIN_ID SIU02481.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="chp1" /locus_tag="BQ2027_MB3852" /note="Mb3852, -, len: 404 aa. Equivalent to Rv3822, len: 404 aa, from Mycobacterium tuberculosis strain H37Rv, (99.3% identity in 404 aa overlap). Conserved hypothetical protein, similar in part to hypothetical proteins from Mycobacterium leprae: Q9CC62|ML1232 (358 aa) FASTA scores: opt: 601, E(): 1.1e-25, (36.7% identity in 335 aa overlap); and Q49633|B1170_F3_112 (391 aa) FASTA scores: opt: 601, E(): 1.2e-25, (36.25% identity in 347 aa overlap). Also similar to P71862|Rv3539|MTCY03C7.17c PPE FAMILY PROTEIN from Mycobacterium tuberculosis (479 aa), FASTA scores: opt: 547, E(): 1.3e-22, (38.1% identity in 281 aa overlap); O50440|Rv1184c|MTV005.20c (359 aa); O06828|Rv1430|MTCY493.24c (528 aa); O53642|Rv0159c|MTV032.02c (468 aa); etc. Mb3852 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="InterPro:IPR013228" /db_xref="InterPro:IPR029058" /db_xref="UniProtKB/TrEMBL:A0A1R3Y5D5" BEGIN 1 MKCPGVSDCV ATVRHDNVFA IAAGLRWSAA VPPLHKGDAV TKLLVGAIAG GMLAYAAILG 61 DGIASADTAL IVPGTAPSPY GPLRSLYHFN PAMQPQIGAN YYTPTATRHV VSYPGSFWPV 121 TGLNSPTVGS SVSAGTNNLD AAIRSTDGPI FVAGLSQGTL VLDREQARLA NDPTAPPPGQ 181 LTFIKAGDPN NLLWRAFRPG THVPIIDYTV PAPVESQYDT INIVGQYDIF SDPPNRPGNL 241 LADLNAIAAG GYYGHSATAF SDPARVAPRD ITTTTNSLGA TTTTYFIRTD QLPLVRALVD 301 MAGLPPQAAG TVDAALRPII DRAYQPGPAP AVNPRDLVQG IRGIPAIAPA IAIPIGSTTG 361 ASAATSTAAA TAAATNALRG ANVGPGANKA LSMVRGLLPK GKKH //