LOCUS       SIU02395.1               448 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 possible
            triacylglycerol synthase (diacylglycerol acyltransferase)
            protein.
ACCESSION   LT708304-3809
PROTEIN_ID  SIU02395.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3766C"
                     /note="Mb3766c, -, len: 448 aa. Equivalent to Rv3740c,
                     len: 448 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.8% identity in 448 aa overlap). Conserved hypothetical
                     protein, highly similar to several other Mycobacterium
                     tuberculosis hypothetical proteins e.g.
                     O69701|Y1D4_MYCTU|Rv3734c|MT3839|MTV025.082c (454 aa)
                     FASTA scores: opt: 1917, E(): 2.3e-112, (61.4% identity in
                     451 aa overlap); Q50680|YM85_MYCTU|Rv2285|MT2343|MTCY339.2
                     5c (445 aa) FASTA scores: opt: 858, E(): 3.4e-46, (37.4%
                     identity in 460 aa overlap);
                     Q10554|Y895_MYCTU|Rv0895|MT0919|MTCY31.23 (505 aa), FASTA
                     scores: opt: 767, E(): 1.9e-40, (44.3% identity in 467 aa
                     overlap); MTCY31_25; MTCY28_26; MTCY493_29; MTCY21B4_43;
                     MTCY8D5_16; MTCY3A2_28; MTV013_8; MTY13E12_33; MTV013_9;
                     MTY20B11_9; etc. Also similar to Q9RIU8|SCM11.13c
                     HYPOTHETICAL 47.1 KDA PROTEIN from Streptomyces coelicolor
                     (446 aa), FASTA scores: opt: 319, E(): 1.7e-12, (30.9%
                     identity in 453 aa overlap). Mb3766c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:A0A1R3Y6M1"
                     /db_xref="InterPro:IPR004255"
                     /db_xref="InterPro:IPR009721"
                     /db_xref="InterPro:IPR014292"
                     /db_xref="InterPro:IPR023213"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y6M1"
BEGIN
        1 MSPIDALFLS AESREHPLHV GALQLFEPPA GAGRGFVRET YQAMLQCREI APLFRKRPTS
       61 LHGALINLGW STDADVDLGY HARRSALPAP GRVRELLELT SRLHSNLLDR HRPLWETHVI
      121 EGLRDGRFAI YSKMHHALVD GVSGLTLMRQ PMTTDPIEGK LRTAWSPATQ HTAIKRRRGR
      181 LQQLGGMLGS VAGLAPSTLR LARSALIEQQ LTLPFGAPHT MLNVAVGGAR RCAAQSWPLD
      241 RVKAVKDAAG VSLNDVVLAM CAGALREYLD DNDALPDTPL VAMVPVSLRT DRDSVGGNMV
      301 GAVLCNLATH LDDPADRLNA IHASMRGNKN VLSQLPRAQA LAVSLLLLSP AALNTLPGLA
      361 KATPPPFNVC ISNVPGAREP LYFNGARMVG NYPMSLVLDG QALNITLTST ADSLDFGVVG
      421 CCRSVPHVQR VLSHLETSLK ELERAVGL
//