LOCUS       SIU02145.1               107 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Transcriptional
            regulator, PadR family protein.
ACCESSION   LT708304-3559
PROTEIN_ID  SIU02145.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3518"
                     /note="Mb3518, -, len: 107 aa. Equivalent to Rv3488, len:
                     107 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.1% identity in 107 aa overlap). Hypothetical protein,
                     similar to various bacterial proteins e.g. O28730|AF1542
                     CONSERVED HYPOTHETICAL PROTEIN from Archaeoglobus fulgidus
                     (101 aa), FASTA scores: opt: 321, E(): 6.4e-15, (50.55%
                     identity in 87 aa overlap); O50207 SQ1_IV (FRAGMENT) from
                     Rhodococcus erythropolis (59 aa), FASTA scores: opt: 298,
                     E(): 1.4e-13, (71.2% identity in 59 aa overlap);
                     Q9KFB0|BH0575 BH0575 PROTEIN from Bacillus halodurans (102
                     aa), FASTA scores: opt: 294, E(): 4.1e-13, (43.15%
                     identity in 95 aa overlap); etc. Also similar to M.
                     tuberculosis P71704|Rv0047c|MTCY21D4.10c (180 aa) (37.8%
                     identity in 82 aa overlap). Protein product from Mb3518
                     detected using SWATH mass spectrometry. Mb3518 found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="InterPro:IPR005149"
                     /db_xref="InterPro:IPR036388"
                     /db_xref="InterPro:IPR036390"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y5Z2"
BEGIN
        1 MREFQRAAVR LHILHHAADN EVHGAWLTQE LSRHGYRVSP GTLYPTLHRL EADGLLVSEQ
       61 RVVDGRARRV YRATPAGRAA LTEDRRALEE LAREVLGRQS HTAGNGT
//