LOCUS       SIU02028.1               130 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Roadblock/
            LC7 protein, putative GTPase-activating (GAP) component
            of G-protein-coupled receptor (GPCR) system protein.
ACCESSION   LT708304-3442
PROTEIN_ID  SIU02028.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3399C"
                     /note="Mb3399c, -, len: 130 aa. Equivalent to Rv3364c,
                     len: 130 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 130 aa overlap). Conserved
                     hypothetical protein, highly similar to others from
                     Streptomyces coelicolor e.g. O86524|SC1C2.24c (137 aa),
                     FASTA scores: opt: 466, E(): 1.3e-22, (58.6% identity in
                     116 aa overlap); O86521|SC1C2.20c (140 aa), FASTA scores:
                     opt: 445, E(): 2.7e-21, (56.9% identity in 116 aa
                     overlap); Q9KZI6|SCG8A.13c (145 aa), FASTA scores: opt:
                     341, E(): 9.5e-15, (51.3% identity in 113 aa overlap);
                     etc. Protein product from Mb3399c detected using shotgun
                     mass spectrometry and SWATH mass spectrometry. Mb3399c
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="InterPro:IPR004942"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y461"
BEGIN
        1 MKARLPDSPL DWLVSKFARE VPGVAHALLV SVDGLPVAAS EHLPRERADQ LAAVTSGLAS
       61 LAGGAAQLFD GGQVLQSVVE MQNGYLLLMQ VGDGSALAAL AATGCDIGQI GYEMAILVER
      121 VGGVVQSCRR
//