LOCUS       SIU01861.1               285 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Metallopeptidase 
            protein.
ACCESSION   LT708304-3275
PROTEIN_ID  SIU01861.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB3232C"
                     /note="Mb3232c, -, len: 285 aa. Equivalent to Rv3207c,
                     len: 285 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.6% identity in 285 aa overlap). Hypothetical protein,
                     highly similar but shorter (57 aa) to Q9CCG9|ML0816
                     HYPOTHETICAL PROTEIN from Mycobacterium leprae (341 aa),
                     FASTA scores: opt: 1676, E(): 9.7e-96, (81.0% identity in
                     284 aa overlap). Also similar to C-terminus of
                     Q9FBI6|SCP8.36 HYPOTHETICAL PROTEIN from Streptomyces
                     coelicolor (559 aa), FASTA scores: opt: 426, E(): 8.4e-19,
                     (37.35% identity in 281 aa overlap); and similar to other
                     hypothetical proteins (generally membrane proteins) e.g.
                     Q9K456|SC2H12.28C PUTATIVE MEMBRANE PROTEIN from
                     Streptomyces coelicolor (314 aa), FASTA scores: opt: 341,
                     E(): 8.8e-14, (29.75% identity in 296 aa overlap).
                     Contains neutral zinc metallopeptidases, zinc-binding
                     region signature (PS00142). Protein product from Mb3232c
                     detected using SWATH mass spectrometry. Mb3232c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y3F7"
                     /db_xref="InterPro:IPR006026"
                     /db_xref="InterPro:IPR022603"
                     /db_xref="InterPro:IPR024079"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y3F7"
BEGIN
        1 MSTYGWRAYA LPVLMVLTTV VVYQTVTGTS TPRPAAAQTV RDSPAIGVVG TAILDAPPRG
       61 LAVFDANLPA GTLPDGGPFT EAGDKTWRVV PGTTPQVGQG TVKVFRYTVE IENGLDPTMY
      121 GGDNAFAQMV DQTLTNPKGW THNPQFAFVR IDSGKPNFRI SLVSPTTVRG GCGYEFRLET
      181 SCYNPSFGGM DRQSRVFINE ARWVRGAVPF EGDVGSYRQY VINHEVGHAI GYLRHEPCDQ
      241 QGGLAPVMMQ QTFSTSNDDA AKFDPDFVKA DGKTCRFNPW PYPIP
//