LOCUS SIU01776.1 344 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Nitroreductase protein. ACCESSION LT708304-3190 PROTEIN_ID SIU01776.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB3150" /note="Mb3150, -, len: 344 aa. Equivalent to Rv3127, len: 344 aa, from Mycobacterium tuberculosis strain H37Rv, (99.7% identity in 344 aa overlap). Hypothetical protein, highly similar to Mycobacterium tuberculosis protein O53476|Rv2032|MTV018.19 (331 aa), FASTA scores: opt: 1212, E(): 6e-69, (56.7% identity in 321 aa overlap), and also similar to P95195|MTCY03A2.27c (332 aa), FASTA scores: opt: 521, E(): 1.6e-25; (35.0% identity in 326 aa overlap). Some similarity to C-terminal half of hypothetical Mycobacterium tuberculosis proteins. Protein product from Mb3150 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb3150 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:A0A1R3Y3W2" /db_xref="InterPro:IPR000415" /db_xref="UniProtKB/TrEMBL:A0A1R3Y3W2" /experiment="experimental evidence, no additional details recorded" BEGIN 1 MLKNAVLLAC RAPSVHNSQP WRWVAESGSE HTTVHLFVNR HRTVPATDHS GRQAIISCGA 61 VLDHLRIAMT AAHWQANITR FPQPNQPDQL ATVECSPIDH VTAGQRNRAQ AILQRRTDRL 121 PFDSPMYWHL FEPALRDAVD KDVAMLDVVS DDQRTRLVVA SQLSEVLRRD DPYYHAELEW 181 WTSPFVLAHG VPPDTLASDA ERLRVDLGRD FPVRSYQNRR AELADDRSKV LVLSTPSDTR 241 ADALRCGEVL STILLECTMA GMATCTLTHL IESSDSRDIV RGLTRQRGEP QALIRVGIAP 301 PLAAVPAPTP RRPLDSVLQI RQTPEKGRNA SDRNARETGW FSPP //