LOCUS       SIU01466.1               812 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 CRISPR-
            associated protein, Csm1 family protein.
ACCESSION   LT708304-2880
PROTEIN_ID  SIU01466.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="cas10"
                     /locus_tag="BQ2027_MB2847C"
                     /note="Mb2847c, -, len: 812 aa. Equivalent to Rv2823c,
                     len: 809 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.6% identity in 812 aa overlap). Conserved hypothetical
                     protein, similar in part to others e.g.
                     Q9X2D1|TM1811Thermotoga maritima (717 aa), FASTA scores:
                     opt: 401, E(): 3.6e-18, (27.15% identity in 773 aa
                     overlap); O27154|MTH1082 CONSERVED HYPOTHETICAL PROTEIN
                     from Methanothermobacter thermautotrophicus (822 aa),
                     FASTA scores: opt: 306, E(): 6e-12, (25.55% identity in
                     872 aa overlap); Q59066|MJ1672 HYPOTHETICAL PROTEIN from
                     Methanococcus jannaschii (800 aa), FASTA scores: opt: 302,
                     E(): 1.1e-11, (24.9% identity in 812 aa overlap); etc.
                     REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a 9
                     bp insertion (*-cggcgatgt) leads to a longer product
                     compared to its homolog in Mycobacterium tuberculosis
                     strain H37Rv."
                     /db_xref="InterPro:IPR000160"
                     /db_xref="InterPro:IPR003607"
                     /db_xref="InterPro:IPR013408"
                     /db_xref="InterPro:IPR041062"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y339"
BEGIN
        1 MNPQLIEAII GCLLHDIGKP VQRAALGYPG RHSAIGRAFM KKVWLRDSRN PSQFTDEVDE
       61 ADIGVSDRRI LDAISYHHSS ALRTAAENGR LAADAPAYIA YIADNIAAGT DRRKADSDDG
      121 HGASTWDPDT PLYSMFNRFG SGTANLAFAP EMLDDRKPIN IPSPRRIEFD KDRYAAIVNK
      181 LKAILVDLER SDTYLASLLN VLEATLSFVP SSTDASEVVD VSLFDHLKLT GALGACIWHY
      241 LQATGQSDFK SALFDKQDTF YNEKAFLLTT FDVSGIQDFI YTIHSSGAAK MLRARSFYLE
      301 MLTEHLIDEL LARVGLSRAN LNYSGGGHAY LLLPNTESAR KSVEQFEREA NDWLLENFAT
      361 RLFIATGSVP LAANDLMRRP NESASQASNR ALRYSGLYRE LSEQLSAKKL ARYSADQLRE
      421 LNSRDHDGQK GDRECSVCHT VNRTVSADDE PKCSLCQALT AASSQIQSES RRFLLISDGA
      481 TKGLPLPFGA TLTFCSRADA DKALQQPQTR RRYAKNKFFA GECLGTGLWV GDYVAQMEFG
      541 DYVKRASGIA RLGVLRLDVD NLGQAFTHGF MEQGNGKFNT ISRTAAFSRM LSLFFRQHIN
      601 YVLARPKLRP ITGDDPARPR EATIIYSGGD DVFVVGAWDD VIEFGIELRE RFHEFTQGKL
      661 TVSAGIGMFP DKYPISVMAR EVGDLEDAAK SLPGKNGVAL FDREFTFGWD ELLSKVIEEK
      721 YRHIADYFSG NEERGMAFIY KLLELLAERD DRITKARWVY FLTRMRNPTG DTAPFQQFAN
      781 RLHQWFQDPT DAKQLKTALH LYIYRTRKEE SE
//