LOCUS       SIU01454.1               226 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PUTATIVE
            TRANSPOSASE [FIRST PART] protein.
ACCESSION   LT708304-2868
PROTEIN_ID  SIU01454.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2835"
                     /note="Mb2835, -, len: 226 aa. Similar to 5' end of
                     Rv2812, len: 469 aa, from Mycobacterium tuberculosis
                     strain H37Rv, (92.4% identity in 224 aa overlap). Putative
                     transposase for IS1604, similar to putative transposases
                     and hypothetical proteins e.g. Q9EZM2|PUTATIVE TRANSPOSASE
                     from Mycobacterium paratuberculosis (395 aa), FASTA
                     scores: opt: 329, E(): 3e-13, (27.05% identity in 362 aa
                     overlap); CAC46499 PUTATIVE TRANSPOSASE PROTEIN from
                     Rhizobium meliloti (Sinorhizobium meliloti) (390 aa),
                     FASTA scores: opt: 327, E(): 3.9e-13, (30.5% identity in
                     367 aa overlap); etc. Contains possible helix-turn-helix
                     motif at aa 50-71 (Score 1140, +3.07 SD).
                     REMARK-M.bovis-M.tuberculosis: In Mycobacterium
                     tuberculosis strain H37Rv, Rv2812 exists as a single gene.
                     In Mycobacterium bovis, a frameshift due to a 2 bp
                     deletion (tg-*) splits Rv2812 into 2 parts, Mb2835 and
                     Mb2836."
                     /db_xref="GOA:A0A1R3Y2B1"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y2B1"
BEGIN
        1 MAVGDDEEKV RAERARAIGL FRYQLIWEAA DAAHSTKQRG KMVRELASRE HTDPFGRRVR
       61 ISRQTIDRWI RGWRAGGFDA LVPNPRQCTP RTPAEVLELA VALRRENPQR TAAAIRRILR
      121 TQLGWAPDER TLQRNFHRLG LTGATTGSAP AVFGRFEAEH PNALWTGDVL HGIRIDLRKT
      181 YLFAFLDDHS RLVPGYRGPC RGHGAAGRRT APGAGLPRRA QRGVCR
//