LOCUS       SIU01408.1               394 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 ppe
            family protein ppe43 protein.
ACCESSION   LT708304-2822
PROTEIN_ID  SIU01408.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="PPE43"
                     /locus_tag="BQ2027_MB2790C"
                     /note="Mb2790c, PPE43, len: 394 aa. Equivalent to Rv2768c,
                     len: 394 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.7% identity in 394 aa overlap). Member of the
                     Mycobacterium tuberculosis PPE family, highly similar to
                     many e.g. upstream ORF O33312|Rv2770c|MTV002.35c (402 aa),
                     FASTA scores: opt: 1135, E(): 6.1e-51, (62.15% identity in
                     391 aa overlap); and P96362|Rv1039c|MTCY10G2.10 from M.
                     tuberculosis (391 aa), FASTA scores: opt: 1721, E():
                     6.8e-81, (70.35% identity in 398 aa overlap). Equivalent
                     to AAK47157 from Mycobacterium tuberculosis strain CDC1551
                     (462 aa) but shorter 68 aa."
                     /db_xref="InterPro:IPR000030"
                     /db_xref="InterPro:IPR022171"
                     /db_xref="InterPro:IPR038332"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y2K0"
BEGIN
        1 MDFGALPPEI NSTRMYAGAG AAPLMAAGAT WNGLAVELST TASSVESVIM QLTTEQWLGP
       61 ASMSMVVAAQ PYLAWLTYTA ESAAHAAAQA MASAAAFEAA FAMTVPPAEV AANRALLAAL
      121 VATNVLGQNT PAIMATEAHY GEMWAQDALA MYGYAASSAA AGRLNPLITP SQTANMAGLA
      181 GQAAAVSHAA AASTVQQVGL GSLISNLPNA VMGFASPLTS AADAAGLGGI IQDIEELLGI
      241 TFVQNAINGA VNTTAWFVMA TIRNAVFLGH AFAALNPATV TAAADAVPAA AAAAGLAHTV
      301 TPVGVGGASL TASLGEASSV GGLSVPAGWS TAAPAMTSGT TALEGSGWAV PEEAGPVAAM
      361 PGMAGISGAA KGAGAYAGPR YGFKPIVMPK QVVV
//