LOCUS       SIU01215.1               884 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Protein
            containing domains DUF404, DUF407, DUF403 protein.
ACCESSION   LT708304-2629
PROTEIN_ID  SIU01215.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2597"
                     /note="Mb2597, -, len: 884 aa. Equivalent to Rv2567, len:
                     884 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.9% identity in 884 aa overlap). Conserved hypothetical
                     ala-, leu-rich protein, equivalent to
                     O53121|ML2679|MLCB1913.13 HYPOTHETICAL PROTEIN from
                     Mycobacterium leprae (893 aa), FASTA scores: opt: 4326,
                     E(): 0, (75.2% identity in 883 aa overlap); and similar to
                     Q49755|YO11_MYCLE|ML0605|MLCL536.05c|U1937B|B1937_F1_4
                     HYPOTHETICAL 61.8 KDA PROTEIN from Mycobacterium leprae
                     (561 aa), FASTA scores: opt: 758, E(): 1.2e-38, (32.2%
                     identity in 537 aa overlap). Also similar to others e.g.
                     Q9HUN7|PA4927 HYPOTHETICAL PROTEIN from Pseudomonas
                     aeruginosa (830 aa), FASTA scores: opt: 1247, E():
                     2.2e-68, (38.25% identity in 831 aa overlap);
                     Q98HG7|MLL2876 HYPOTHETICAL PROTEIN from Rhizobium loti
                     (Mesorhizobium loti) (803 aa), FASTA scores: opt: 937,
                     E(): 1.9e-49, (32.15% identity in 828 aa overlap);
                     CAC47419|SMC04057 CONSERVED HYPOTHETICAL PROTEIN from
                     Rhizobium meliloti (Sinorhizobium meliloti) (802 aa),
                     FASTA scores: opt: 900, E(): 3.4e-47, (30.85% identity in
                     852 aa overlap); etc. And similar to
                     P71732|YO11_MYCTU|Rv2411c|MT2484|MTCY253.09 CONSERVED
                     HYPOTHETICAL PROTEIN from Mycobacterium tuberculosis (551
                     aa), FASTA scores: opt: 781, E(): 4.6e-40, (33.75%
                     identity in 495 aa overlap). Protein product from Mb2597
                     detected using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb2597 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="InterPro:IPR007296"
                     /db_xref="InterPro:IPR025841"
                     /db_xref="UniProtKB/Swiss-Prot:P59974"
BEGIN
        1 MAPSASAATN GYDVDRLLAG YRTARAQETL FDLRDGPGAG YDEFVDDDGN VRPTWTELAD
       61 AVAERGKAGL DRLRSVVHSL IDHDGITYTA IDAHRDALTG DHDLEPGPWR LDPLPLVISA
      121 ADWEVLEAGL VQRSRLLDAI LADLYGPRSM LTEGVLPPEM LFAHPGYVRA ANGIQMPGRH
      181 QLFMHACDLS RLPDGTFQVN ADWTQAPSGS GYAMADRRVV AHAVPDLYEE LAPRPTTPFA
      241 QALRLALIDA APDVAQDPVV VVLSPGIYSE TAFDQAYLAT LLGFPLVESA DLVVRDGKLW
      301 MRSLGTLKRV DVVLRRVDAH YADPLDLRAD SRLGVVGLVE AQHRGTVTVV NTLGSGILEN
      361 PGLLRFLPQL SERLLDESPL LHTAPVYWGG IASERSHLLA NVSSLLIKST VSGETLVGPT
      421 LSSAQLADLA VRIEAMPWQW VGQELPQFSS APTNHAGVLS SAGVGMRLFT VAQRSGYAPM
      481 IGGLGYVLAP GPAAYTLKTV AAKDIWVRPT ERAHAEVITV PVLAPPAKTG AGTWAVSSPR
      541 VLSDLFWMGR YGERAENMAR LLIVTRERYH VFRHQQDTDE SECVPVLMAA LGKITGYDTA
      601 TGAGSAYDRA DMIAVAPSTL WSLTVDPDRP GSLVQSVEGL ALAARAVRDQ LSNDTWMVLA
      661 NVERAVEHKS DPPQSLAEAD AVLASAQAET LAGMLTLSGV AGESMVHDVG WTMMDIGKRI
      721 ERGLWLTALL QATLSTVRHP AAEQAIIEAT LVACESSVIY RRRTVGKFSV AAVTELMLFD
      781 AQNPRSLVYQ LERLRADLKD LPGSSGSSRP ERMVDEMNTR LRRSHPEELE EVSADGLRAE
      841 LAELLAGIHA SLRDVADVLT ATQLALPGGM QPLWGPDQRR VMPA
//