LOCUS SIU01117.1 217 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 CONSERVED HYPOTHETICAL PROTEIN protein. ACCESSION LT708304-2531 PROTEIN_ID SIU01117.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB2501C" /note="Mb2501c, -, len: 217 aa. Equivalent to Rv2474c, len: 217 aa, from Mycobacterium tuberculosis strain H37Rv, (99.5% identity in 217 aa overlap). Hypothetical protein. Shows weak similarity with Q9L246|SC6D10.18c HYPOTHETICAL 24.9 KDA PROTEIN from Streptomyces coelicolor (238 aa), FASTA scores: opt: 111, E(): 5.6, (30% identity in 233 aa overlap), BLASTP scores: Score= 135, E= 3.5e-07, P= 3.5e-07, Identities= 55/182 (30%). Protein product from Mb2501c detected using SWATH mass spectrometry. Mb2501c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="InterPro:IPR016601" /db_xref="UniProtKB/TrEMBL:A0A1R3Y1P6" BEGIN 1 MVERGLWLPD PAHRADLATF VDHALRLDDV AVIRIRARST GLLSAWVATG FDVLASRVVA 61 GKVRPDDLSV AARSLAHGLA TTDASGYVDP GYSMDSAWRG GLPPESGFTY LDDVPARVML 121 DLAHRGARLA KEHGSSAGPP VSLLDQEVIQ VSSADVVVGL PMRCVFALTA MGFLPQSAET 181 ISADELIRVR ISPAWLRLDA RFGSVYRHRG HAALVLR //