LOCUS       SIU01095.1               201 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            MOLYBDOPTERIN-GUANINE DINUCLEOTIDE BIOSYNTHESIS PROTEIN
            A MOBA protein.
ACCESSION   LT708304-2509
PROTEIN_ID  SIU01095.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="mobA"
                     /locus_tag="BQ2027_MB2480C"
                     /note="Mb2480c, mobA, len: 201 aa. Equivalent to Rv2453c,
                     len: 201 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 201 aa overlap). Probable mobA,
                     molybdopterin-guanine dinucleotide biosynthesis protein A,
                     similar to others e.g. Q9F8G7 from Carboxydothermus
                     hydrogenoformans (224 aa), FASTA scores: opt: 249, E():
                     3.9e-08, (30.6% identity in 173 aa overlap);
                     P95645|MOBA_RHOSH|MOB|Y09560 from Rhodobacter sphaeroides
                     (199 aa), FASTA scores: opt: 240, E(): 1.2e-07, (33.9%
                     identity in 186 aa overlap); Q9X7K0|MOBA_RHOCA from
                     Rhodobacter capsulatus (Rhodopseudomonas capsulata) (191
                     aa), FASTA scores: opt: 217, E(): 2.9e-06, (37.4% identity
                     in 123 aa overlap); etc. BELONGS TO THE MOBA FAMILY.
                     Protein product from Mb2480c detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb2480c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:P65403"
                     /db_xref="InterPro:IPR013482"
                     /db_xref="InterPro:IPR025877"
                     /db_xref="InterPro:IPR029044"
                     /db_xref="UniProtKB/Swiss-Prot:P65403"
BEGIN
        1 MAELAPDTVP LAGVVLAGGE SRRMGRDKAT LPLPGGTTTL VEHMVGILGQ RCAPVFVMAA
       61 PGQPLPTLPV PVLRDELPGL GPLPATGRGL RAAAEAGVRL AFVCAVDMPY LTVELIEDLA
      121 RRAVQTDAEV VLPWDGRNHY LAAVYRTDLA DRVDTLVGAG ERKMSALVDA SDALRIVMAD
      181 SRPLTNVNSA AGLHAPMQPG R
//