LOCUS       SIU01057.1               223 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 glucosyl-
            3-phosphoglycerate phosphatase gpgp protein.
ACCESSION   LT708304-2471
PROTEIN_ID  SIU01057.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="gpgp"
                     /locus_tag="BQ2027_MB2442C"
                     /note="Mb2442c, -, len: 223 aa. Equivalent to Rv2419c,
                     len: 223 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.6% identity in 223 aa overlap). Probable
                     phosphoglycerate mutase (EC 5.4.2.1), equivalent to
                     Q9CC00|ML1452 POSSIBLE PHOSPHOGLYCERATE MUTASE from
                     Mycobacterium leprae (224 aa), FASTA scores: opt: 1206,
                     E(): 8.8e-68, (80.35% identity in 224 aa overlap). Also
                     highly similar to Q9RDL0|SCC123.14c PUTATIVE
                     PHOSPHOGLYCERATE MUTASE from Streptomyces coelicolor (223
                     aa), FASTA scores: opt: 431, E(): 9.4e-20, (40.85%
                     identity in 213 aa overlap); and similar to others e.g.
                     Q9RVD2|DR1097 from Deinococcus radiodurans (232 aa), FASTA
                     scores: opt: 291, E(): 4.6e-11, (39.3% identity in 173 aa
                     overlap); etc. Some similarity to
                     Q10512|Rv2228c|Y019_MYCTU|MT2287|MTcy427.09c hypothetical
                     39.2 kd protein from Mycobacterium tuberculosis (364 aa)
                     FASTA scores: opt: 196, E(): 2.8e-06, (45.6% identity in
                     79 aa overlap). Contains PS00175 Phosphoglycerate mutase
                     family phosphohistidine signature. BELONGS TO THE
                     PHOSPHOGLYCERATE MUTASE FAMILY. Protein product from
                     Mb2442c detected using shotgun mass spectrometry and SWATH
                     mass spectrometry. Mb2442c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:A0A1R3Y1I3"
                     /db_xref="InterPro:IPR001345"
                     /db_xref="InterPro:IPR013078"
                     /db_xref="InterPro:IPR029033"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3Y1I3"
BEGIN
        1 MRARRLVMLR HGQTDYNVGS RMQGQLDTEL SELGRTQAVA AAEVLGKRQP LLIVSSDLRR
       61 AYDTAVKLGE RTGLVVRVDT RLRETHLGDW QGLTHAQIDA DAPGARLAWR EDATWAPHGG
      121 ESRVDVAARS RPLVAELVAS EPEWGGADEP DRPVVLVAHG GLIAVLSAAL LKLPVANWPA
      181 LGGMGNASWT QLSGHWAPGS DFESIRWRLD VWNASAQVSS DVL
//