LOCUS       SIU00927.1               334 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 5'-
            methylthioadenosine nucleosidase (EC @ S-adenosylhomocysteine
            nucleosidase (EC protein.
ACCESSION   LT708304-2341
PROTEIN_ID  SIU00927.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB2315C"
                     /EC_number="3.2.2.16"
                     /EC_number="3.2.2.9"
                     /note="Mb2315c, -, len: 334 aa. Similar to Rv2293c and
                     Rv2292c, len: 246 aa and 74 aa, from Mycobacterium
                     tuberculosis strain H37Rv, (92.2% identity in 245 aa
                     overlap and 100.0% identity in 74 aa overlap). Conserved
                     hypothetical protein; some similarity to hypothetical
                     protein (299 aa) AAK24237.1| (AE005897) belonging to
                     phosphorylase family [Caulobacter crescentus] (33%
                     identity in 131 aa overlap). Possible lipoprotein: signal
                     peptide at N-terminus. REMARK-M.bovis-M.tuberculosis: In
                     Mycobacterium tuberculosis strain H37Rv, Rv2293c and
                     Rv2292c exist as 2 genes. In Mycobacterium bovis, a single
                     base insertion (*-g) results in a single product which is
                     more similar to Rv2293c. Mb2315c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="GOA:P64978"
                     /db_xref="InterPro:IPR000845"
                     /db_xref="InterPro:IPR035994"
                     /db_xref="UniProtKB/Swiss-Prot:P64978"
BEGIN
        1 MGAPLRHCLL VAAALSLGCG VAAADPGYVA NVIPCEQRTL VLSAFPAEAD AVLAHTALDA
       61 NPVVVADRRR YYLGSISGKK VIVAMTGIGL VNATNTTETA FARFTCASSI AIAAVMFSGV
      121 AGGAGRTSIG DVAIPARWTL DNGATFRGVD PGMLATAQTL SVVLDNINTL GNPVCLCRNV
      181 PVVRLNHLGR QPQLFVGGDG SSSDKNNGQA FPCIPNGGSV FGCQPCSAPD RSLGYTGNFF
      241 QAAGPWLKNA LISNLNIVST VNPGFDAVDQ ETAAAQAVAD AHGVPFLGIR GMSDGPGDPL
      301 HLPGFPVQFF VYKQIAANNA ARVTEAFLQN WAGV
//