LOCUS SIU00798.1 143 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Transcriptional regulator MraZ protein. ACCESSION LT708304-2212 PROTEIN_ID SIU00798.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="mraZ" /locus_tag="BQ2027_MB2190C" /note="Mb2190c, -, len: 143 aa. Equivalent to Rv2166c, len: 143 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 143 aa overlap). Conserved hypothetical protein; shows strong similarity to several hypothetical bacterial proteins such as YLLB_BACSU P55343. Is equivalent to Mycobacterium leprae hypothetical protein ML0905 (143 aa, 92% identity) MLCB268.11c >sp|O69561|YL66_MYCLE HYPOTHETICAL 16.1 KDA PROTEIN ML0905 >gi|3080482|emb|CAA18677.1|(AL022602) >gi|13092975|emb|CAC31286.1|(AL583920). FASTA scores: ML0905|ML0905 conserved hypothetical protein (143 aa) opt: 873, E(): 3.1e-52; 92.254% identity in 142 aa overlap; YLLB_BACSU P55343 hypothetical 16.6 kd protein (143 aa) opt: 340, E(): 3.6e-17; (35.0% identity in 143 aa overlap). BELONGS TO THE YABB (E.COLI), YLLB (B.SUBTILIS), MG221 (M.GENITALIUM) FAMILY Protein product from Mb2190c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb2190c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /db_xref="GOA:P65437" /db_xref="InterPro:IPR003444" /db_xref="InterPro:IPR007159" /db_xref="InterPro:IPR020603" /db_xref="InterPro:IPR035642" /db_xref="InterPro:IPR035644" /db_xref="InterPro:IPR037914" /db_xref="InterPro:IPR038619" /db_xref="UniProtKB/Swiss-Prot:P65437" BEGIN 1 MFLGTYTPKL DDKGRLTLPA KFRDALAGGL MVTKSQDHSL AVYPRAAFEQ LARRASKAPR 61 SNPEARAFLR NLAAGTDEQH PDSQGRITLS ADHRRYASLS KDCVVIGAVD YLEIWDAQAW 121 QNYQQIHEEN FSAASDEALG DIF //