LOCUS       SIU00583.1               454 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 13E12
            repeat family protein protein.
ACCESSION   LT708304-1996
PROTEIN_ID  SIU00583.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1980"
                     /note="Mb1980, -, len: 454 aa. Equivalent to Rv1945, len:
                     454 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.780% identity in 454 aa overlap). Member of
                     Mycobacterium tuberculosis REP13E12 repeat family. Similar
                     to several others, best with Rv1148c|Z95584|MTCI65.15 (482
                     aa), FASTA score: opt: 2954, E(): 0, (97.1% identity in
                     454 aa overlap). Contains possible helix-turn-helix motif
                     at aa 74-95 (+2.90 SD). Mb1980 found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /db_xref="InterPro:IPR003615"
                     /db_xref="InterPro:IPR003870"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XZS1"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MRSDTREEIS AALDAYHASL SRVLDLKCDA LTTPELLACL QRLEVERRRQ GAAEHALINQ
       61 LAGQACEEEL GGTLRTALAN RLHITPGEAS RRIAEAEDLG ERRALTGEPL PAQLTATAAA
      121 QREGKIGREH IKEIQAFFKE LSAAVDLGIR EAAEAQLAEL ATSRRPDHLH GLATQLMDWL
      181 HPDGNFSDQE RARKRGITMG KQEFDGMSRI SGLLTPELRA TIEAVLAKLA APGACNPDDQ
      241 TPLVDDTPDA DAVRRDTRSQ AQRHHDGLLA GLRGLLASGE LGQHRGLPVT VVVSTTLKEL
      301 EAATGKGVTG GGSRVPMSDL IRMASNAHHY LALFDGAKPL ALYHTKRLAS PAQRIMLYAK
      361 DRGCSRPGCD APAYHSEVHH VTPWTTTHRT DINDLTLACG PDNRLVEKGW KTRKNAKGDT
      421 EWLPPAHLDH GQPRINRYHH PEKILCEPDD DEPH
//