LOCUS       SIU00570.1               165 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            THIOL PEROXIDASE TPX protein.
ACCESSION   LT708304-1983
PROTEIN_ID  SIU00570.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="tpx"
                     /locus_tag="BQ2027_MB1967"
                     /standard_name="cfp20"
                     /note="Mb1967, tpx, len: 165 aa. Equivalent to Rv1932,
                     len: 165 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 165 aa overlap). Probable tpx
                     (alternate gene name: cfp20), thiol peroxidase (EC
                     1.11.1.-) similar to TPX_ECOLI|P37901 thiol peroxidase (EC
                     1.11.1.-) (p20) from Escherichia coli (167 aa), fasta
                     scores: opt: 535, E(): 7.3e-25, (52.4% identity in 164 aa
                     overlap). There are four other related enzymes in M.
                     tuberculosis: Rv2428, Rv2521, Rv2238c, Rv1608c. Protein
                     product from Mb1967 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb1967 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /db_xref="GOA:P66953"
                     /db_xref="InterPro:IPR002065"
                     /db_xref="InterPro:IPR013740"
                     /db_xref="InterPro:IPR013766"
                     /db_xref="InterPro:IPR018219"
                     /db_xref="InterPro:IPR036249"
                     /db_xref="UniProtKB/Swiss-Prot:P66953"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MAQITLRGNA INTVGELPAV GSPAPAFTLT GGDLGVISSD QFRGKSVLLN IFPSVDTPVC
       61 ATSVRTFDER AAASGATVLC VSKDLPFAQK RFCGAEGTEN VMPASAFRDS FGEDYGVTIA
      121 DGPMAGLLAR AIVVIGADGN VAYTELVPEI AQEPNYEAAL AALGA
//