LOCUS SIU00469.1 288 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Probable hydrolase protein. ACCESSION LT708304-1882 PROTEIN_ID SIU00469.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="lipz" /locus_tag="BQ2027_MB1865" /note="Mb1865, -, len: 288 aa. Equivalent to Rv1834, len: 288 aa, from Mycobacterium tuberculosis strain H37Rv, (99.7% identity in 288 aa overlap). Probable hydrolase (EC 3.-.-.-), some similarity to haloalkane dehalogenases and D16262 hypothetical 38.9 kd protein (335 aa), FASTA scores: opt: 507, E(): 7.6e-28, (33.0% identity in 300 aa overlap). Mb1865 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /db_xref="GOA:A0A1R3XZJ0" /db_xref="InterPro:IPR000073" /db_xref="InterPro:IPR000639" /db_xref="InterPro:IPR029058" /db_xref="UniProtKB/TrEMBL:A0A1R3XZJ0" BEGIN 1 MTSPSVREWR DGGRWLPTAV GKVFVRSGPG DTPTMLLLHG YPSSSFDFRA VIPHLTGQAW 61 VTMDFLGFGL SDKPRPHRYS LLEQAHLVET VVAHTVTGAV VVLAHDMGTS VTTELLARDL 121 DGRLPFDLRR AVLSNGSVIL ERASLRPIQK VLRSPLGPVA ARLVSRGGFT RGFGRIFSPA 181 HPLSAQEAQA QWELLCYNDG NRIPHLLISY LDERIRHAQR WHGAVRDWPK PLGFVWGLDD 241 PVATTNVLNG LRELRPSAAV VELPGLGHYP QAEAPKAYAE AALSLLVD //