LOCUS       SIU00392.1               820 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PE-
            PGRS FAMILY PROTEIN WAG22B [SECOND PART] protein.
ACCESSION   LT708304-1805
PROTEIN_ID  SIU00392.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="wag22b"
                     /locus_tag="BQ2027_MB1789C"
                     /note="Mb1789c, wag22b, len: 820 aa. Equivalent to 3' end
                     of Rv1759c, len: 914 aa, from Mycobacterium tuberculosis
                     strain H37Rv, (100% identity in 820 aa overlap). wag22,
                     antigen member of the Mycobacterium tuberculosis PE
                     family, PGRS subfamily of gly-rich proteins, highly
                     similar to others e.g. MT1367|Q10637 hypothetical
                     glycine-rich 49.6 kd protein from Mycobacterium
                     tuberculosis (603 aa), FASTA scores: opt: 2010, E(): 0,
                     (53.0% identity in 724 aa overlap); etc.
                     REMARK-M.bovis-M.tuberculosis: In Mycobacterium
                     tuberculosis strain H37Rv, Rv1759c exists as a single
                     gene. In Mycobacterium bovis, a single base deletion (c-*)
                     splits wag22 into 2 parts, wag22a and wag22b."
                     /db_xref="InterPro:IPR000084"
                     /db_xref="UniProtKB/Swiss-Prot:P0A687"
BEGIN
        1 MTPLLNSINA PVLAATGRPL IGNGANGAPG TGANGGDAGW LIGNGGAGGS GAKGANGGAG
       61 GPGGAAGLFG NGGAGGAGGT ATANNGIGGA GGAGGSAMLF GAGGAGGAGG AATSLVGGIG
      121 GTGGTGGNAG MLAGAAGAGG AGGFSFSTAG GAGGAGGAGG LFTTGGVGGA GGQGHTGGAG
      181 GAGGAGGLFG AGGMGGAGGF GDHGTLGTGG AGGDGGGGGL FGAGGDGGAG GSGLTTGGAA
      241 GNGGNAGTLS LGAAGGAGGT GGAGGTVFGG GKGGAGGAGG NAGMLFGSGG GGGTGGFGFA
      301 AGGQGGVGGS AGMLSGSGGS GGAGGSGGPA GTAAGGAGGA GGAPGLIGNG GNGGNGGESG
      361 GTGGVGGAGG NAVLIGNGGE GGIGALAGKS GFGGFGGLLL GADGYNAPES TSPWHNLQQD
      421 ILSFINEPTE ALTGRPLIGN GDSGTPGTGD DGGAGGWLFG NGGNGGAGAA GTNGSAGGAG
      481 GAGGILFGTG GAGGAGGVGT AGAGGAGGAG GSAFLIGSGG TGGVGGAATT TGGVGGAGGN
      541 AGLLIGAAGL GGCGGGAFTA GVTTGGAGGT GGAAGLFANG GAGGAGGTGS TAGGAGGAGG
      601 AGGLYAHGGT GGPGGNGGST GAGGTGGAGG PGGLYGAGGS GGAGGHGGMA GGGGGVGGNA
      661 GSLTLNASGG AGGSGGSSLS GKAGAGGAGG SAGLFYGSGG AGGNGGYSLN GTGGDGGTGG
      721 AGQITGLRSG FGGAGGAGGA SDTGAGGNGG AGGKAGLYGN GGDGGAGGDG ATSGKGGAGG
      781 NAVVIGNGGN GGNAGKAGGT AGAGGAGGLV LGRDGQHGLT
//