LOCUS SIU00178.1 678 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 ppe family protein ppe21 protein. ACCESSION LT708304-1591 PROTEIN_ID SIU00178.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="PPE21" /locus_tag="BQ2027_MB1575C" /note="Mb1575c, PPE21, len: 678 aa. Equivalent to Rv1548c, len: 678 aa, from Mycobacterium tuberculosis strain H37Rv, (99.7% identity in 678 aa overlap). Member of the M. tuberculosis PPE family, similar to several e.g. YHS6_MYCTU|P42611 hypothetical 50.6 kd protein in hsp65 3' region (517 aa), FASTA scores: opt:1142, E(): 0, (40.6% identity in 616 aa overlap); also similar to MTCY31.06c (54.9% identity in 381 aa overlap)." /db_xref="InterPro:IPR000030" /db_xref="InterPro:IPR002989" /db_xref="InterPro:IPR038332" /db_xref="UniProtKB/TrEMBL:A0A1R3XYN6" BEGIN 1 MNFSVLPPEI NSALMFAGAG PGPMLAAASA WTGLAGDLGS AAASFSAVTS QLATGSWQGP 61 ASAAMTGAAA SYARWLTTAA AQAEQAAGQA QAAVSAFEAA LAATVHPGAV SANRGRLRSL 121 VASNLLGQNA PAIAAVEAVY EQMWAADVAA MLGYHGEASA VALSLTPFTP SPSAAATPGG 181 AVIIAGFPFL DLGNVTIGGF NLASGNLGLG NLGSFNPGSA NTGSVNLGNA NIGDLNLGSG 241 NIGSYNLGGG NTGDLNPGSG NTGTLNWGSG NIGSYNLGGG NLGSYNLGSG NTGDTNFGGG 301 NTGNLNVGGG NTGNSNFGFG NTGNVNFGNG NTGDTNFGSG NLGSGNIGFG NKGSHNIGFG 361 NSGNNNIGFG LTGDNQIGFG ALNSGSGNLG FGNSGNGNIG FFNSGNNNIG MGNSGNGVGA 421 LSVEFGSSAE RSSGFGNSGE LSTGIGNSGQ LSTGWFNSAT TSTGWFNSGT TNTGWFNSGT 481 TNTGIGNSGG NLVTGSMGLF NSGHTNTGSF NAGSMNTGDF NSGNVNTGYF NSGNINTGFF 541 NSGDLNTGLF NSVNQPVQNS GWLHTGTNNS GYANAGTFNS GFDNNARDEH AEFVTGNSGL 601 ANVGNYNAGI INVGDHLSGF RNSVPTITGT ANISGFVNAG TSISGFFNFG SLMSGFANFD 661 DEVSGYLNGD SRASGWIH //