LOCUS       SIT99998.1               340 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            OXIDOREDUCTASE protein.
ACCESSION   LT708304-1410
PROTEIN_ID  SIT99998.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1395"
                     /note="Mb1395, -, len: 340 aa. Equivalent to Rv1360, len:
                     340 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 340 aa overlap). Probable oxidoreductase
                     (EC 1.-.-.-). Similar to Q49598|G1002714 coenzyme
                     F420-dependent n5, n10-methylenetetrahydromethanopterin
                     reductase from Methanopyrus kandleri (349 aa), FASTA
                     scores: opt: 264, E(): 4.4e-11, (26.3% identity in 323 aa
                     overlap). Protein product from Mb1395 detected using
                     shotgun mass spectrometry and SWATH mass spectrometry.
                     Mb1395 found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
                     /db_xref="GOA:P64832"
                     /db_xref="InterPro:IPR011251"
                     /db_xref="InterPro:IPR019919"
                     /db_xref="InterPro:IPR036661"
                     /db_xref="UniProtKB/Swiss-Prot:P64832"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MGGARRLKLD GSIPNQLARA ADAAVALERN GFDGGWTAEA SHDPFLPLLL AAEHTSRLEL
       61 GTNIAVAFAR NPMIVANVGW DLQTYSKGRL ILGLGTQIRP HIEKRFSMPW GHPARRMREF
      121 VAALRAIWLA WQDGTKLCFE GEFYTHKIMT PMFTPEPQPY PVPRVFIAAV GEAMTEMCGE
      181 VADGHLGHPM VSKRYLTEVS VPALLRGLAR SGRDRSAFEV SCEVMVATGA DDAELAAACT
      241 ATRKQIAFYG STPAYRKVLE QHGWGDLHPE LHRLSKLGEW EAMGGLIDDE MLGAFAVVGP
      301 VDTIAGALRN RCEGVVDRVL PIFMAASQEC INAALQDFRR
//