LOCUS       SIT99779.1               482 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 13E12
            repeat family protein protein.
ACCESSION   LT708304-1191
PROTEIN_ID  SIT99779.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1179C"
                     /note="Mb1179c, -, len: 482 aa. Equivalent to Rv1148c,
                     len: 482 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 482 aa overlap). Conserved hypothetical
                     ORF in REP13E12 degenerate repeat, nearly identical to
                     other hypothetical Mycobacterium tuberculosis proteins in
                     REP13E12 repeats, although similarity extends upstream
                     past proposed f-Met start. Very similar to other REP13E12
                     proteins e.g. Rv1945, Rv3467, Rv0094c, Rv1128c etc.
                     Mb1179c found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
                     /db_xref="InterPro:IPR003615"
                     /db_xref="InterPro:IPR003870"
                     /db_xref="UniProtKB/Swiss-Prot:P0A5E0"
BEGIN
        1 MSETFCLTDH SEPMTARFLS VVLRRIRGMR SDTREEISAA LDAYHASLSR VLDLKCDALT
       61 TPELLACLQR LEVERRRQGA AEHALINQLA GQACEEELGG TLRTALANRL HITPGEASRR
      121 IAEAEDLGER RALTGEPLPA QLTATAAAQR EGKIGREHIK EIQAFFKELS AAVDLGIREA
      181 AEAQLAELAT SRRPDHLHGL ATQLMDWLHP DGNFSDQERA RKRGITMGKQ EFDGMSRISG
      241 LLTPELRATI EAVLAKLAAP GACNPDDQTP LVDDTPDADA VRRDTRSQAQ RNHDAFLAAL
      301 RGLLASGELG QHKGLPVTIV VSTTLKELEA ATGKGVTGGG SRVPMSDLIR MASHANHYLA
      361 LFDGAKPLAL YHTKRLASPA QRIMLYAKDR GCSRPGCDAP AYHSEVHHVT PWTTTHRTDI
      421 NDLTLACGPD NRLVEKGWKT RKNAHGDTEW LPPPHLDHGQ PRINRYHHPA KILCEQDDDE
      481 PH
//