LOCUS       SIT99697.1               587 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Predicted
            membrane protein (DUF2319) protein.
ACCESSION   LT708304-1109
PROTEIN_ID  SIT99697.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB1098C"
                     /note="Mb1098c, -, len: 587 aa. Equivalent to Rv1069c,
                     len: 587 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100% identity in 587 aa overlap). Conserved hypothetical
                     protein, hydrophobic regions in N-terminal domain. Similar
                     in part to O07136|B1306.04C B1306.04c protein from
                     Mycobacterium leprae (89 aa), FASTA scores: opt: 229, E():
                     1.3e-07, (54.2% identity in 72 aa overlap). Protein
                     product from Mb1098c detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb1098c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /db_xref="GOA:A0A1R3XX94"
                     /db_xref="InterPro:IPR012037"
                     /db_xref="InterPro:IPR027787"
                     /db_xref="InterPro:IPR027788"
                     /db_xref="UniProtKB/TrEMBL:A0A1R3XX94"
BEGIN
        1 MTEPAAATTT NASDEPATGA EQAVDTAATP QTPEPQPIRS TWWIRHYTFT GTAMGLVFVW
       61 FSMTPSLLPR GPLFQGLVSG ICGAFGYGLG VFAVWLVRYM RSHNSSPPPP RWAWPPLIAV
      121 GAVGMVGMAV QFHVWQDDVR DLMGVEHLRW YDYPLAAALS LVVLFTLVEI GQFIRWLFRF
      181 LVGQVDRIAP FRVSAAIVVV LLVVLTITLL NGVVLKFAMN SMNSTFAAVN NEMNPDSAPP
      241 KTPLRSGGPG SLVSWESLGH QGRIFVHSGP TIADLTAFNG TPAVEPIRTY AGLNSADGIM
      301 ATAELAAREL ARTGGLRRAV VAVATSTGTG WINEAEASAL EYMYNGDTAI VSMQYSFLPS
      361 WLSFLVDKEN ARHAGEALFE AVDKLIRQLP ESQRPKLVVF GESLGSFGGE APFMNLNNIL
      421 ARTDGALFSG PTFNNTVWNS LTANRDAGSP QWLPIYDDGR NVRFVARARD LQRPDAPWGR
      481 PRVVYLQHAS DPIAWWTPRL LFREPDWLRE QRGYDVLPQT RWIPVVTFVQ VSADMAVATH
      541 VPDGHGHRYV ATVADGWAAV LSPPGWTQQK TERLQPLLHA NAKPFGS
//